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Cyclin E is a member of the cyclin family.
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mir-133 is a type of non-coding RNA called a microRNA that was first experimentally characterised in mice. Homologues have since been discovered in several other species including invertebrates such as the fruitfly Drosophila melanogaster. Each species often encodes multiple microRNAs with identical or similar mature sequence. For example, in the human genome there are three known miR-133 genes: miR-133a-1, miR-133a-2 and miR-133b found on chromosomes 18, 20 and 6 respectively. The mature sequence is excised from the 3' arm of the hairpin. miR-133 is expressed in muscle tissue and appears to repress the expression of non-muscle genes.
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miR-224 is a family of microRNA precursors found in mammals, including humans. The ~22 nucleotide mature miRNA sequence is excised from the precursor hairpin by the enzyme Dicer.
In molecular biology mir-383 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms.
In molecular biology mir-652 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms, with expression levels of miRNAs and respective target mRNAs negatively correlated.
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References
- ↑ Huang V, Place RF, Portnoy V, Wang J, Qi Z, Jia Z, et al. (2012). "Upregulation of Cyclin B1 by miRNA and its implications in cancer". Nucleic Acids Res. 40 (4): 1695–707. doi:10.1093/nar/gkr934. PMC 3287204 . PMID 22053081.
- ↑ Martin J, Jenkins RH, Bennagi R, Krupa A, Phillips AO, Bowen T, et al. (2011). "Post-transcriptional regulation of Transforming Growth Factor Beta-1 by microRNA-744". PLOS ONE. 6 (10): e25044. Bibcode:2011PLoSO...625044M. doi: 10.1371/journal.pone.0025044 . PMC 3186795 . PMID 21991303.
- ↑ Vislovukh, A; Kratassiouk, G; Porto, E; Gralievska, N; Beldiman, C; Pinna, G; El'skaya, A; Harel-Bellan, A; Negrutskii, B; Groisman, I (11 June 2013). "Proto-oncogenic isoform A2 of eukaryotic translation elongation factor eEF1 is a target of miR-663 and miR-744". British Journal of Cancer. 108 (11): 2304–11. doi:10.1038/bjc.2013.243. PMC 3681015 . PMID 23695020.
- ↑ Vislovukh, A; Kratassiouk, G; Porto, E; Gralievska, N; Beldiman, C; Pinna, G; El'skaya, A; Harel-Bellan, A; Negrutskii, B; Groisman, I (11 June 2013). "Proto-oncogenic isoform A2 of eukaryotic translation elongation factor eEF1 is a target of miR-663 and miR-744". British Journal of Cancer. 108 (11): 2304–11. doi:10.1038/bjc.2013.243. PMC 3681015 . PMID 23695020.
