The Molecular and Behavioral Neuroscience Institute (MBNI) at the University of Michigan (UM) is an interdisciplinary research institute, which played a key role in the development of general systems theory. [1] Formerly the Mental Health Research Institute, over the years it developed a specific interest in neuroscience and biological psychiatry and was subsequently renamed in the new millennium. The Reagents of the University of Michigan plan to demolish the building by September 25th, 2024. [2]
The institute was established as Mental Health Research Institute at the University of Michigan in 1955 with the goal of "applying scientific methods to the study of human behavior." [3] Many neuroscientists have conducted research at the MBNI, including Huda Akil. In the 1950s, initial members of the Society for General Systems Research (SGSR) were hired by the MBNI, such as biologist and founding director of the institute James Grier Miller, mathematician Anatol Rapoport, physicist John Platt, urban planner Richard L. Meier, economist Walter Cannon, neurophysiologist Ralph Gerard, among others like Margaret Mead and Richard F. Ericson. [1]
Neuroscience is the scientific study of the nervous system, its functions and disorders. It is a multidisciplinary science that combines physiology, anatomy, molecular biology, developmental biology, cytology, psychology, physics, computer science, chemistry, medicine, statistics, and mathematical modeling to understand the fundamental and emergent properties of neurons, glia and neural circuits. The understanding of the biological basis of learning, memory, behavior, perception, and consciousness has been described by Eric Kandel as the "epic challenge" of the biological sciences.
The National Institute of Neurological Disorders and Stroke (NINDS) is a part of the U.S. National Institutes of Health (NIH). It conducts and funds research on brain and nervous system disorders and has a budget of just over US$2.03 billion. The mission of NINDS is "to reduce the burden of neurological disease—a burden borne by every age group, every segment of society, and people all over the world". NINDS has established two major branches for research: an extramural branch that funds studies outside the NIH, and an intramural branch that funds research inside the NIH. Most of NINDS' budget goes to fund extramural research. NINDS' basic science research focuses on studies of the fundamental biology of the brain and nervous system, genetics, neurodegeneration, learning and memory, motor control, brain repair, and synapses. NINDS also funds clinical research related to diseases and disorders of the brain and nervous system, e.g. AIDS, Alzheimer's disease, epilepsy, muscular dystrophy, multiple sclerosis, Parkinson's disease, spinal cord injury, stroke, and traumatic brain injury.
An academic discipline or field of study is a branch of knowledge, taught and researched as part of higher education. A scholar's discipline is commonly defined by the university faculties and learned societies to which they belong and the academic journals in which they publish research.
Systems science, also referred to as systems research, or, simply, systems, is a transdisciplinary field that is concerned with understanding simple and complex systems in nature and society, which leads to the advancements of formal, natural, social, and applied attributions throughout engineering, technology and science, itself.
A neuroscientist is a scientist who has specialised knowledge in neuroscience, a branch of biology that deals with the physiology, biochemistry, psychology, anatomy and molecular biology of neurons, neural circuits, and glial cells and especially their behavioral, biological, and psychological aspect in health and disease.
Paul Donald MacLean was an American physician and neuroscientist who made significant contributions in the fields of physiology, psychiatry, and brain research through his work at Yale Medical School and the National Institute of Mental Health. MacLean's evolutionary triune brain theory proposed that the human brain was in reality three brains in one: the reptilian complex, the limbic system, and the neocortex.
The Helen Wills Neuroscience Institute (HWNI) at the University of California, Berkeley was created in 1997, through a bequest from eight-time Wimbledon champion Helen Wills Moody, an alumna of UC Berkeley.
Neuroinformatics is the emergent field that combines informatics and neuroscience. Neuroinformatics is related with neuroscience data and information processing by artificial neural networks. There are three main directions where neuroinformatics has to be applied:
James Grier Miller was an American biologist, a pioneer of systems science and academic administrator, who originated the modern use of the term "behavioral science", founded and directed the multi-disciplinary Mental Health Research Institute at the University of Michigan, and originated the living systems theory.
The Max Planck Institute for Biological Cybernetics is located in Tübingen, Baden-Württemberg, Germany. It is one of 80 institutes in the Max Planck Society. It was founded in 1968.
Stuart Anspach Umpleby is an American cybernetician and professor in the Department of Management and Director of the Research Program in Social and Organizational Learning in the School of Business at the George Washington University.
Peter Andrew Corning is an American biologist, consultant, and complex systems scientist, Director of the Institute for the Study of Complex Systems, in Seattle, Washington. He is known especially for his work on the causal role of synergy in evolution.
Steven Edward Hyman is Director of the Stanley Center for Psychiatric Research at the Broad Institute of MIT and Harvard in Cambridge, Massachusetts. He is also Harvard University Distinguished Service Professor of Stem Cell and Regenerative Biology. Hyman was Provost of Harvard University from 2001 to 2011 and before that Director of the U.S. National Institute of Mental Health (NIMH) from 1996 to 2001. Hyman received the 2016 Rhoda and Bernard Sarnat International Prize in Mental Health from the National Academy of Medicine for "leadership in furthering understanding and treatment of psychiatric disorders as biological diseases".
Stephen W. Porges is an American psychologist and neuroscientist. He is the Professor of Psychiatry at the University of North Carolina at Chapel Hill. Porges is also currently Director of the Kinsey Institute Traumatic Stress Research Consortium at Indiana University Bloomington, which studies trauma.
Thomas Roland Insel is an American neuroscientist, psychiatrist, entrepreneur, and author who led the National Institute of Mental Health (NIMH) from 2002 until November 2015. Prior to becoming Director of NIMH, he was the founding Director of the Center for Behavioral Neuroscience at Emory University in Atlanta, Georgia. He is best known for research on oxytocin and vasopressin, two peptide hormones implicated in complex social behaviors, such as parental care and attachment. He announced on Sept. 15, 2015, that he was resigning as the director of the NIMH to join the Life Science division of Google X. On May 8, 2017, CNBC reported that he had left Verily Life Sciences. Insel is a Co-founder with Richard Klausner and Paul Dagum of a digital mental health company named "Mindstrong," a Bay-area startup. He has also co-founded Humanest Care, NeuraWell Therapeutics, and MindSite News and is a member of the scientific advisory board for Compass Pathways, a company that is developing the psychedelic drug psilocybin to treat depression and other mental health disorders. His book, Healing: Our Path from Mental Illness to Mental Health was published by Penguin Random House in February, 2022.
Psychology encompasses a vast domain, and includes many different approaches to the study of mental processes and behavior. Below are the major areas of inquiry that taken together constitute psychology. A comprehensive list of the sub-fields and areas within psychology can be found at the list of psychology topics and list of psychology disciplines.
Huda Akil is a Syrian-American neuroscientist whose research has contributed to the understanding of the neurobiology of emotions, including pain, anxiety, depression, and substance abuse. Akil and her colleagues are best known for providing the first physiological evidence for a role of endorphins in the brain and demonstrating that endorphins are activated by stress and can cause pain inhibition.
Stanley J. Watson Jr. is a neuroscientist whose research focuses on regulation by the central nervous system of behavior in the brains of individuals with severe mental illness. He is the co-director of the Molecular and Behavioral Neuroscience Institute with Huda Akil and the Ralph Waldo Gerard Professor of Neuroscience and Psychiatry at the University of Michigan. He is also the co-director of the University of Michigan node of the Pritzker Neuropsychiatric Disorders Research Consortium.
The Princeton Neuroscience Institute (PNI) is a center for neuroscience research at Princeton University. Founded in the spring of 2004, the PNI serves as a "stimulus for teaching and research in neuroscience and related fields" and "places particular emphasis on the close connection between theory, modeling, and experimentation using the most advanced technologies." It often partners with Princeton University's departments of Psychology and Molecular Biology.