Momordin (saponin)

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Momordin is one of several saponins derived from oleanolic acid, a triterpenoid. These chemical compounds are found in some plants of the genus Momordica , which includes the bitter melon (M. charantia) and the balsam apple (M. balsamina), as well as in other Asian herbal medicine plants such as Kochia scoparia and Ampelopsis radix . [1] [2]

Momordins include:

See also

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5
H
10
O
5
or (–CHOH–)
5
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References

  1. 1 2 Matsuda, H.; Li, Y.; Yamahara, J.; Yoshikawa, M. (1999). "Inhibition of gastric emptying by triterpene saponin, momordin Ic, in mice: Roles of blood glucose, capsaicin-sensitive sensory nerves, and central nervous system". The Journal of Pharmacology and Experimental Therapeutics. 289 (2): 729–734. PMID   10215646.
  2. 1 2 3 4 Iwamoto, M.; Okabe, H.; Yamauchi, T. (1985). "Studies on the constituents of Momordica cochinchinensis Spreng. II. Isolation and characterization of the root saponins, Momordins I, II and III". Chemical & Pharmaceutical Bulletin. 33: 1–7. doi: 10.1248/cpb.33.1 .
  3. Juhyung Lee; Chi-Hoon Park; Wook-Hwan Kim; Yun Ha Hwang; Kyungchae jeong & Chul-Hak Yang (2006). "Inhibitory effects of momordin I derivatives on the formation of Fos-Jun-AP-1 DNA complex". Bull. Korean Chem. Soc. 27 (4): 535. doi: 10.5012/bkcs.2006.27.4.535 . ISSN   0253-2964.
  4. 1 2 3 4 5 6 Khesort Nantachit; Patoomratana Tuchinda (2009). "Antimicrobial Activity of Hexane and Dichloromethane Extracts from Momordica cochinchinensis (Lour.) Spreng Leaves" (PDF). Thai Pharmaceutical and Health Science Journal. 4 (1): 15–20. ISSN   1905-3460. Archived from the original (PDF) on 2011-08-24. Retrieved 2011-01-01.
  5. Kim, N. Y.; Lee, M. K.; Park, M. J.; Kim, S. J.; Park, H. J.; Choi, J. W.; Kim, S. H.; Cho, S. Y.; Lee, J. S. (2005). "Momordin Ic and Oleanolic Acid from Kochiae Fructus Reduce Carbon Tetrachloride-Induced Hepatotoxicity in Rats". Journal of Medicinal Food. 8 (2): 177–183. doi:10.1089/jmf.2005.8.177. PMID   16117609.
  6. Momordin Ie catalog entry at Trading Chem. Accessed 2011-01-01.
  7. Momordin IIc catalog entry from NextBio. Accessed on 2011-01-01.
  8. Simon, A. S.; Tóth, G. B.; Duddeck, H.; Soliman, H. S. M.; Mahmoud, I. I.; Samir, H. (2006). "Glycosides fromBougainvillea glabra". Natural Product Research. 20 (1): 63–67. doi:10.1080/14786410500162351. PMID   16286311. S2CID   26781556.
  9. Momordin IIe catalog page at Look Chemical. Accessed on 2011-01-01.