Morogoro virus

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Morogoro virus
Virus classification OOjs UI icon edit-ltr.svg
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Negarnaviricota
Class: Bunyaviricetes
Order: Hareavirales
Family: Arenaviridae
Genus: Mammarenavirus
Virus:
Morogoro virus

Morogoro virus is an East African arenavirus infecting the multimammate mouse (Mastomys natalensis). [1] The virus is genetically closely related to Lassa virus, known to cause Lassa fever in humans. Morogoro virus, however, does not seem to infect humans. [1] Transmission of Morogoro virus between mice is assumed to occur via direct and indirect contact. [2] Infected animals pass a latent period of 7 days and subsequently shed the virus for about 30 days, after which they recover and develop lifelong antibodies. [3] Transmission may also be possible from infected mothers to offspring and through sexual contact, as this has been suggested for other arenaviruses. [4] [5]

References

  1. 1 2 Günther S, Hoofd G, Charrel R, Röser C, Becker-Ziaja B, Lloyd G, Sabuni C, Verhagen R, van der Groen G, Kennis J, Katakweba A, Machang'u R, Makundi R, Leirs H (December 2009). "Mopeia virus-related arenavirus in natal multimammate mice, Morogoro, Tanzania". Emerg Infect Dis. 15 (12): 2008–2012. doi:10.3201/eid1512.090864. PMC   3044542 . PMID   19961688.
  2. ↑ Borremans B, Leirs H, Gryseels S, Günther S, Makundi R, de Bellocq JG (August 2011). "Presence of Mopeia virus, an African arenavirus, related to biotope and individual rodent host characteristics: implications for virus transmission". Vector Borne Zootic Dis. 11 (8): 1125–1131. doi:10.1089/vbz.2010.0010. PMID   21142956.
  3. ↑ Borremans B, Vossen R, Becker-Ziaja B, Gryseels S, Hughes N, Van Gestel M, Van Houtte N, Günther S, Leirs H (29 May 2015). "Shedding dynamics of Morogoro virus, an African arenavirus closely related to Lassa virus, in its natural reservoir host Mastomys natalensis". Sci Rep. 5 10445. Bibcode:2015NatSR...510445B. doi:10.1038/srep10445. PMC   4448520 . PMID   26022445.
  4. ↑ Fichet-Calvet E, Becker-Ziaja B, Koivogui L, Günther S (September 2014). "Lassa serology in natural populations of rodents and horizontal transmission". Vector Borne Zoonotic Dis. 14 (9): 665–674. doi:10.1089/vbz.2013.1484. PMC   4170823 . PMID   25229705.
  5. ↑ Webb PA, Justines G, Johnson KM (1975). "Infection of wild and laboratory animals with Machupo and Latino viruses". Bull World Health Organ. 52 (4–6): 493–499. PMC   2366657 . PMID   182399.
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