Mucinous cystic neoplasm

Last updated October 29, 2025

A mucinous cystic neoplasm is an abnormal and excessive growth of tissue (neoplasm) that typically has elements of mucin and one or more cysts. By location, they include:

Pancreatic mucinous cystic neoplasm: These lesions are benign, though there is a high rate of progression to cancer. As such, surgery should be pursued when feasible. The rate of malignancy present in MCN is about 10 percent.^[1] If resection is performed before invasive malignancy develops, the prognosis is excellent. The extent of invasion is the single most important prognostic factor in predicting survival.^[2]
Mucinous cystic neoplasms of the liver are a type of liver cancer in which tissue similar to the stroma of ovary occurs.^[3]

References

↑ Elta, GH; Enestvedt, BK; Sauer, BG; Lennon, AM (April 2018). "ACG Clinical Guideline: Diagnosis and Management of Pancreatic Cysts". The American Journal of Gastroenterology. 113 (4): 464–479. doi:10.1038/ajg.2018.14. PMID 29485131. S2CID 3584079.
↑ Zamboni, G; Scarpa, A; Bogina, G; Iacono, C; Bassi, C; Talamini, G; Sessa, F; Capella, C; Solcia, E; Rickaert, F; Mariuzzi, GM; Klöppel, G (April 1999). "Mucinous cystic tumors of the pancreas: clinicopathological features, prognosis, and relationship to other mucinous cystic tumors". The American Journal of Surgical Pathology. 23 (4): 410–22. doi:10.1097/00000478-199904000-00005. PMID 10199470.
↑ Kishida, N; Shinoda, M; Masugi, Y; Itano, O; Fujii-Nishimura, Y; Ueno, A; Kitago, M; Hibi, T; Abe, Y; Yagi, H; Tanimoto, A; Tanabe, M; Sakamaoto, M; Kitagawa, Y (21 July 2014). "Cystic tumor of the liver without ovarian-like stroma or bile duct communication: two case reports and a review of the literature". World Journal of Surgical Oncology. 12: 229. doi: 10.1186/1477-7819-12-229 . PMC 4119182 . PMID 25047921.

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[Elta-1] Elta, GH; Enestvedt, BK; Sauer, BG; Lennon, AM (April 2018). "ACG Clinical Guideline: Diagnosis and Management of Pancreatic Cysts". The American Journal of Gastroenterology. 113 (4): 464–479. doi:10.1038/ajg.2018.14. PMID 29485131. S2CID 3584079.

[Zamboni-2] Zamboni, G; Scarpa, A; Bogina, G; Iacono, C; Bassi, C; Talamini, G; Sessa, F; Capella, C; Solcia, E; Rickaert, F; Mariuzzi, GM; Klöppel, G (April 1999). "Mucinous cystic tumors of the pancreas: clinicopathological features, prognosis, and relationship to other mucinous cystic tumors". The American Journal of Surgical Pathology. 23 (4): 410–22. doi:10.1097/00000478-199904000-00005. PMID 10199470.

[3] Kishida, N; Shinoda, M; Masugi, Y; Itano, O; Fujii-Nishimura, Y; Ueno, A; Kitago, M; Hibi, T; Abe, Y; Yagi, H; Tanimoto, A; Tanabe, M; Sakamaoto, M; Kitagawa, Y (21 July 2014). "Cystic tumor of the liver without ovarian-like stroma or bile duct communication: two case reports and a review of the literature". World Journal of Surgical Oncology. 12: 229. doi: 10.1186/1477-7819-12-229 . PMC 4119182 . PMID 25047921.

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