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Mate Hidvegi | |
|---|---|
 Mate Hidvegi | |
| Born | 9 November 1955 |
| Nationality | Hungarian |
| Alma mater | Budapest University of Technology and Economics |
| Known for | Fermented wheat germ extract |
| Awards | Jedlik Anyos Prize 2007 |
| Scientific career | |
| Fields | cancer research |
| Institutions | Budapest University of Technology and Economics, freelance |
Mate Hidvegi (born 9 November 1955 in Budapest, Hungary) is a Hungarian biochemist and co-inventor of Avemar and Oncomar, fermented wheat germ extract based nutraceuticals.
Hidvegi was born in Budapest, Hungary, on 9 November 1955. He is the son of György Hidvégi-Hoffmann and Katalin Dávid.[ citation needed ]
He received his Bachelor of Science in 1978 and Master of Science in 1980 from Technology University Budapest. He also received his Doctor of Philosophy from Technology University Budapest in 1983.Then he taught at what is now Budapest University of Technology and Economics from 1984-1987 as assistant professor and since 1992 as professor.[ citation needed ] After finishing university, he worked in the cereal industry and was co-developer of a patented feed advisory system based on near infrared ingredient data. [1] Hidvegi was the pioneer in the development of technologies of mass-production and therapeutic use of instantized herbal extracts in Hungary. Between 1988-1990 Hidvegi was Post-Doctoral Fellow at the Grain Research Laboratory of the Canadian Grain Commission, Winnipeg, Canada.
In 1996 Hidvegi was co-founder of Biromedicina (joint stock company), what is now called The First Hungarian Corporation for Cancer Research and Oncology. The company’s mission was to market Hidvegi's product Avemar, a fermented wheat germ extract-based nutraceutical.
Hidvegi holds a PhD and a Dr. Habil in chemistry, and an honorary professorship at the Jewish University, Budapest.
Hidvegi's first publications were about the theories of the origins of life, and the elaboration of a plausible mechanism for the biogenesis and evolution of biomembranes. He worked out the metabolic map as well as the reaction kinetics of a theoretical first living cell.
Hidvegi invented and hold the patent for the manufacturing process of an alfalfa-based extract (Esterin), which has been claimed to lower serum cholesterol levels (U.S patent 5,277,910 January 11, 1994).
Hidvegi is the co-inventor of a patented fermented wheat germ extract-based nutraceutical known as Avemar. [2] In the U.S., Avemar is classified as a dietary supplement and marketed under the trade name Ave (American BioSciences, Inc.; Blauvelt, NY). In Hungary Avemar as a dietary food for cancer patients.
In 2009 Hidvegi marketed a new dietary food for special medical purposes for cancer patients based on the Avemar, which was sold as Oncomar and (in the U.S.) AvéUltra.
Folate, also known as vitamin B9 and folacin, is one of the B vitamins. Manufactured folic acid, which is converted into folate by the body, is used as a dietary supplement and in food fortification as it is more stable during processing and storage. Folate is required for the body to make DNA and RNA and metabolise amino acids necessary for cell division. As humans cannot make folate, it is required in the diet, making it an essential nutrient. It occurs naturally in many foods. The recommended adult daily intake of folate in the U.S. is 400 micrograms from foods or dietary supplements.
Dietary fiber or roughage is the portion of plant-derived food that cannot be completely broken down by human digestive enzymes. Dietary fibers are diverse in chemical composition, and can be grouped generally by their solubility, viscosity, and fermentability, which affect how fibers are processed in the body. Dietary fiber has two main components: soluble fiber and insoluble fiber, which are components of plant-based foods, such as legumes, whole grains and cereals, vegetables, fruits, and nuts or seeds. A diet high in regular fiber consumption is generally associated with supporting health and lowering the risk of several diseases. Dietary fiber consists of non-starch polysaccharides and other plant components such as cellulose, resistant starch, resistant dextrins, inulin, lignins, chitins, pectins, beta-glucans, and oligosaccharides.
Sourdough or sourdough bread is a bread made by the fermentation of dough using wild lactobacillaceae and yeast. Lactic acid from fermentation imparts a sour taste and improves keeping qualities.
A liposome is a small artificial vesicle, spherical in shape, having at least one lipid bilayer. Due to their hydrophobicity and/or hydrophilicity, biocompatibility, particle size and many other properties, liposomes can be used as drug delivery vehicles for administration of pharmaceutical drugs and nutrients, such as lipid nanoparticles in mRNA vaccines, and DNA vaccines. Liposomes can be prepared by disrupting biological membranes.
A neoplasm is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists in growing abnormally, even if the original trigger is removed. This abnormal growth usually forms a mass, when it may be called a tumour or tumor.
Pálinka is a traditional fruit spirit with origins in the Carpathian Mountains, more exactly known under several names, and invented in the Middle Ages. Protected as a geographical indication of the European Union, only fruit spirits mashed, distilled, matured and bottled in Hungary and similar apricot spirits from four provinces of Austria can be called "pálinka", while "Tótpálinka" refers to wheat-derived beverages. Törkölypálinka, a different product in the legal sense, is a similarly protected pomace spirit that is commonly included with pálinka. While pálinka may be made of any locally grown fruit, the most common ones are plums, apricots, apples, pears, and cherries.
Quercetin is a plant flavonol from the flavonoid group of polyphenols. It is found in many fruits, vegetables, leaves, seeds, and grains; capers, red onions, and kale are common foods containing appreciable amounts of it. It has a bitter flavor and is used as an ingredient in dietary supplements, beverages, and foods.
Ferulic acid is a hydroxycinnamic acid, is an organic compound and a polyphenol with the formula (CH3O)HOC6H3CH=CHCO2H. The name is derived from the genus Ferula, referring to the giant fennel (Ferula communis). Classified as a phenolic phytochemical, ferulic acid is an amber colored solid. Esters of ferulic acid are found in plant cell walls, covalently bonded to hemicellulose such as arabinoxylans.
The vitamin E family comprise four tocotrienols and four tocopherols. The critical chemical structural difference between tocotrienols and tocopherols is that tocotrienols have unsaturated isoprenoid side chains with three carbon-carbon double bonds versus saturated side chains for tocopherols.
Species belonging to the genus Amaranthus have been cultivated for their grains for 8,000 years. Amaranth plants are classified as pseudocereals that are grown for their edible starchy seeds, but they are not in the same botanical family as true cereals, such as wheat and rice. Amaranth species that are still used as a grain are Amaranthus caudatus L., Amaranthus cruentus L., and Amaranthus hypochondriacus L. The yield of grain amaranth is comparable to that of rice or maize.
A DNA repair-deficiency disorder is a medical condition due to reduced functionality of DNA repair.
In food processing, fermentation is the conversion of carbohydrates to alcohol or organic acids using microorganisms—yeasts or bacteria—under anaerobic (oxygen-free) conditions. Fermentation usually implies that the action of microorganisms is desired. The science of fermentation is known as zymology or zymurgy.
Fermented wheat germ extract (FWGE), also called fermented wheat germ powder (FWGP), is a concentrated extract of wheat germ derived from the germ of the wheat plant. FWGE differs from ordinary wheat germ in that it is fermented with baker's yeast to concentrate biologically-active benzoquinones. FWGE is available commercially and is sold under the trade name Avemar. In the U.S., the product is classified as a dietary supplement and is marketed as Awge.
Carbohydrate antigen 19-9 (CA19-9), also known as sialyl-LewisA, is a tetrasaccharide which is usually attached to O-glycans on the surface of cells. It is known to play a role in cell-to-cell recognition processes. It is also a tumor marker used primarily in the management of pancreatic cancer.
The miR-16 microRNA precursor family is a group of related small non-coding RNA genes that regulates gene expression. miR-16, miR-15, mir-195 and miR-497 are related microRNA precursor sequences from the mir-15 gene family. This microRNA family appears to be vertebrate specific and its members have been predicted or experimentally validated in a wide range of vertebrate species.
The 2009–10 season will be Debreceni VSC – TEVA's 17th competitive season, 17th consecutive season in the Soproni Liga and 107th year in existence as a football club.
2,6-Dimethoxybenzoquinone (2,6-DMBQ) is a chemical compound, classified as a benzoquinone, that has been found in Rauvolfia vomitoria and in Tibouchina pulchra.
Ergtoxin is a toxin from the venom of the Mexican scorpion Centruroides noxius. This toxin targets hERG potassium channels.
Nuruk (누룩) is a traditional Korean fermentation starter. It is used to make various types of Korean alcoholic beverages including takju, cheongju, and soju. It is an essential ingredient in Shindari and is mixed with rice. Historically, it was used in a variety of provinces of Korea, including Jeju Island.
Robert A. Newman is an American pharmacologist specializing in molecular biology, drug development, and immunology.
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