Nederlands Herseninstituut | |
Formation | 2005 |
---|---|
Type | Research Institute |
Purpose | Fundamental Neuroscience Research |
Headquarters | Amsterdam, Netherlands |
Location |
|
Official language | English and Dutch |
Parent organization | KNAW |
Staff | ~200 |
Website | nin |
The Netherlands Institute for Neuroscience (NIN) (Dutch: Nederlands Herseninstituut) is a research institute of the Royal Netherlands Academy of Arts and Sciences (KNAW) that carries out neuroscience research with special emphasis on the brain and visual system. Although the institute's focus is on understanding the fundamental mechanisms underlying brain function, its research spans the development, plasticity and aging of the brain and is often linked to clinical research questions. The research program is carried out in 17 research groups. In addition, the NIN includes the Netherlands Brain Bank and the Netherlands Sleep Registry.
The Netherlands Institute for Neuroscience (NIN) came into being on 1 July 2005 as the merger of the Netherlands Institute for Brain Research (NIBR) and the Netherlands Ophthalmic Research Institute (NORI). The NIBR dates back to the beginning of the 20th century. A meeting of the International Association of Academies held in Paris in 1901 led in 1904 to the formation of the International Academic Committee for Brain Research, and the foundation of several institutes for brain research in Europe, including in 1908, the “Netherlands Central Institute for Brain Research”. Under director Prof C. U. Ariëns Kappers (director 1909–1946) and his successors the institute acquired an international reputation as a centre of excellent brain research. Originally oriented to comparative neuroanatomy the institute later became a multidisciplinary centre with outstanding research facilities
The NORI was founded in 1972 as an inter-university institute to perform basic research. The ophthalmogenetic database founded by Prof J.W. Delleman and the systematic functional analysis of the visual system initiated by Prof H. Spekreijse made the institute an internationally recognized centre in vision research. In the late nineties the research objective focused increasingly on the functioning of the visual system and its relation to the brain.
Since 2010 it has run an annual Art of Neuroscience competition. In 2020 seven entries were chosen by Scientific American as Editors’ Picks. [1]
The institute has 17 research groups who are housed in the NIN building and use the (lab)facilities and other services provided by the NIN. The employees of fourteen groups are employed at the NIN and led by director prof. Roelfsema. The employees of three groups are employed at the Amsterdam UMC and (formally) led by Amsterdam UMC management. Currently the groupleaders are: Ingo Willuhn (Amsterdam UMC), Chris De Zeeuw, Alexander Heimel, Inge Huitinga, Andries Kalsbeek (Amsterdam UMC & NIN), Maarten Kamermans, Evgenia Salta, Christian Keysers, Maarten Kole, Christiaan Levelt, Christian Lohmann, Pieter Roelfsema, Serge Dumoulin, Eus Van Someren, Francesca Siclari, Joost Verhaagen, Susanne La Fleur (Amsterdam UMC), Valeria Gazzola.
In November 2020 the institute got funding from the Start2Cure Foundation for a project to investigate the potential of a gene therapy approach to treat multiple sclerosis and to identify the genes involved in the production of myelin and in repairing nerve fibers. [2]
They are involved in research into artificial vision. In December 2020 they published results of their significant study implanting electrodes into macaque monkeys. Shapes of letters were directly transmitted into the brains of the monkeys and they were able to respond to them without actually seeing them. [3]
Many of the institute's scientists are recipients of prestigious grants, awards and distinctions, including European Research Council laureates, VIDI/VICI grant holders. Several of its principal investigators are members of national and international academies: Chris de Zeeuw is a member of the KNAW and Christian Keysers is a member of the Young Academy of Europe.
One of the strong points of the NIN is its research infrastructure. The institute host several two-photon excitation microscopy setups to perform in vivo brain imaging at the cellular and sub-cellular level, high density EEG labs, multi-electrode recording systems. The institute also hosts a large mechanical workshop, which provides technical support to its research staff and helps co-develop new research tools. Additionally, the NIN is an important stakeholder in the state of the art Magnetic resonance imaging Spinoza Centre for Neuroimaging hosting 3T and 7T MRI systems for human neuroscience, which is situated in the same premises.
The Royal Netherlands Academy of Arts and Sciences is an organization dedicated to the advancement of science and literature in the Netherlands. The academy is housed in the Trippenhuis in Amsterdam.
A brain–computer interface (BCI), sometimes called a brain–machine interface (BMI) or smartbrain, is a direct communication pathway between the brain's electrical activity and an external device, most commonly a computer or robotic limb. BCIs are often directed at researching, mapping, assisting, augmenting, or repairing human cognitive or sensory-motor functions. They are often conceptualized as a human–machine interface that skips the intermediary component of the physical movement of body parts, although they also raise the possibility of the erasure of the discreteness of brain and machine. Implementations of BCIs range from non-invasive and partially invasive to invasive, based on how close electrodes get to brain tissue.
Miguel Ângelo Laporta Nicolelis, is a Brazilian scientist, physician and Duke School of Medicine Professor in Neuroscience at Duke University, best known for his pioneering work surrounding brain-computer interface technology.
Brain implants, often referred to as neural implants, are technological devices that connect directly to a biological subject's brain – usually placed on the surface of the brain, or attached to the brain's cortex. A common purpose of modern brain implants and the focus of much current research is establishing a biomedical prosthesis circumventing areas in the brain that have become dysfunctional after a stroke or other head injuries. This includes sensory substitution, e.g., in vision. Other brain implants are used in animal experiments simply to record brain activity for scientific reasons. Some brain implants involve creating interfaces between neural systems and computer chips. This work is part of a wider research field called brain–computer interfaces.
Neuroprosthetics is a discipline related to neuroscience and biomedical engineering concerned with developing neural prostheses. They are sometimes contrasted with a brain–computer interface, which connects the brain to a computer rather than a device meant to replace missing biological functionality.
Edward Vaughan Evarts was an American neuroscientist. He pioneered single-unit recordings from the brains of awake, behaving monkeys.
Nin or NIN may refer to:
Michael Matthias Merzenich is an American neuroscientist and professor emeritus at the University of California, San Francisco. He took the sensory cortex maps developed by his predecessors and refined them using dense micro-electrode mapping techniques. Using this, he definitively showed there to be multiple somatotopic maps of the body in the postcentral sulcus, and multiple tonotopic maps of the acoustic inputs in the superior temporal plane.
Tomaso Armando Poggio, is the Eugene McDermott professor in the Department of Brain and Cognitive Sciences, an investigator at the McGovern Institute for Brain Research, a member of the MIT Computer Science and Artificial Intelligence Laboratory (CSAIL) and director of both the Center for Biological and Computational Learning at MIT and the Center for Brains, Minds, and Machines, a multi-institutional collaboration headquartered at the McGovern Institute since 2013.
Maarten de Rijke is a Dutch computer scientist. His work initially focused on modal logic and knowledge representation, but since the early years of the 21st century he has worked mainly in information retrieval. His work is supported by grants from the Nederlandse Organisatie voor Wetenschappelijk Onderzoek (NWO), public-private partnerships, and the European Commission.
Christian Keysers is a French and German neuroscientist.
Dick Ferdinand Swaab is a Dutch physician and neurobiologist. He is a professor of neurobiology at the University of Amsterdam and was until 2005 Director of the Netherlands Institute for Brain Research of the Royal Netherlands Academy of Arts and Sciences.
Rudolf Nieuwenhuys is a Dutch neuroanatomist, Emeritus Professor of Neuroanatomy and Comparative Neuroanatomy at the Catholic University in Nijmegen. He is recognised for his contribution to the field of comparative neuroanatomy. Professor Nieuwenhuys graduated from the Faculty of Medicine of the University of Amsterdam in 1955 and in 1960 obtained a PhD at the same institute with the dissertation Het Telencephalon der Actinopterygii. He started his research in the field of neuroanatomy in The Netherlands Institute for Neuroscience, Amsterdam, the Netherlands. He is author of important works in neuroanatomy including The Central Nervous System of Vertebrates, The Human Central Nervous System and Towards a New Neuromorphology.
Stentrode is a small stent-mounted electrode array permanently implanted into a blood vessel in the brain, without the need for open brain surgery. It is in clinical trials as a brain–computer interface (BCI) for people with paralyzed or missing limbs, who will use their neural signals or thoughts to control external devices, which currently include computer operating systems. The device may ultimately be used to control powered exoskeletons, robotic prosthesis, computers or other devices.
Peter H. Schiller is a German-born neuroscientist. His is a professor emeritus of Neuroscience in the Department of Brain and Cognitive Sciences at the Massachusetts Institute of Technology (MIT). Schiller is well known for his work on the behavioral, neurophysiological and pharmacological studies of the primate visual and oculomotor systems.
The Royal Netherlands Academy of Arts and Sciences is an organization dedicated to the advancement of science and literature in the Netherlands. The academy is housed in the Trippenhuis in Amsterdam. Founded in 1808, members are appointed for life by co-optation.
Helga (Elga) De Vries is a Dutch neuroimmunologist and a Full Professor in the Department of Molecular Cell Biology and Immunology at Amsterdam University Medical Centers in Amsterdam, The Netherlands. De Vries is a leader in the field of blood brain barrier research. She founded the Dutch Blood Brain Barrier Network and is the President of the International Brain Barrier Society. De Vries’ research explores the interactions between the brain and the immune system and she specifically looks at neurovascular biology in the context of neurodegenerative diseases such as multiple sclerosis and Alzheimer's disease.
Casper Hoogenraad is a Dutch Cell Biologist who specializes in molecular neuroscience. The focus of his research is the basic molecular and cellular mechanisms that regulate the development and function of the brain. As of January 2020, he serves as Vice President of Neuroscience at Genentech Research and Early Development.
Valeria Gazzola is an Italian neuroscientist, associate professor at the Faculty of Social and Behavioral Sciences at the University of Amsterdam (UvA) and member of the Young Academy of Europe. She is also a tenured department head at the Netherlands Institute for Neuroscience (NIN) in Amsterdam, where she leads her own research group and the Social Brain Lab together with neuroscientist Christian Keysers. She is a specialist in the neural basis of empathy and embodied cognition: Her research focusses on how the brain makes individuals sensitive to the actions and emotions of others and how this affects decision-making.
Peter Hagoort is a Dutch neuroscientist who studies the neurobiology of language.