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The Neuroblastoma Society is a UK charity that helps families affected by neuroblastoma by funding research and running a befriending scheme for parents. [1] [2] The charity was set up in 1982 by a group of parents whose children had suffered from or died of neuroblastoma.
Samaritans is a registered charity aimed at providing emotional support to anyone in emotional distress, struggling to cope or at risk of suicide throughout the United Kingdom and the Republic of Ireland, often through its telephone helpline. Its name derives from the biblical Parable of the Good Samaritan although the organisation itself is not religious.
The National Society for the Prevention of Cruelty to Children (NSPCC) is a British child protection charity.
Alex's Lemonade Stand Foundation is an American pediatric cancer charity founded by Alexandra "Alex" Scott, who lived in Connecticut before moving to Pennsylvania. Scott suffered from neuroblastoma.
Young Lives vs Cancer, the operating name for "CLIC Sargent", is a charity in the United Kingdom formed in 2005. Young Lives vs Cancer is a leading UK cancer charity for children, young people and their families. Its care teams provide specialist support across the UK.
Neuroblastoma (NB) is a type of cancer that forms in certain types of nerve tissue. It most frequently starts from one of the adrenal glands but can also develop in the head, neck, chest, abdomen, or spine. Symptoms may include bone pain, a lump in the abdomen, neck, or chest, or a painless bluish lump under the skin.
Spurgeons is a large national children's charity in the United Kingdom, working with vulnerable families, children and young people. It is based in Rushden, with several offices in the UK, and is a registered charity.
Audrey Elizabeth Evans was a British-born American pediatric oncologist who was known as the "Mother of Neuroblastoma". Evans was one of the co-founders of the original Ronald McDonald House in Philadelphia as well as a co-founder of Philadelphia's St. James School. She spent most of her career working at the Children's Hospital of Philadelphia.
Paired-like homeobox 2b (PHOX2B), also known as neuroblastoma Phox (NBPhox), is a protein that in humans is encoded by the PHOX2B gene located on chromosome 4.
N-myc proto-oncogene protein also known as N-Myc or basic helix-loop-helix protein 37 (bHLHe37), is a protein that in humans is encoded by the MYCN gene.
The Band of Parents is a 501(c)(3) nonprofit organization. Formed in July 2007 and incorporated in October 2007, it was founded by approximately 100 parents of young children with neuroblastoma who were treated at Memorial Sloan Kettering Cancer Center (MSKCC). Its purpose is to fund the development of new therapies for neuroblastoma that would not otherwise be pursued by research institutions or the pharmaceutical industry. The organization has become the largest single funder of neuroblastoma research at MSKCC.
Ganglioneuroblastoma is a variant of neuroblastoma that is surrounded by ganglion cells.
Smash Childhood Cancer is a World Community Grid volunteer computing subproject on the BOINC platform. It is based on World Community Grid's Help Childhood Cancer subproject which was a joint effort of Chiba University and the Chiba Cancer Center. Based on the results of that project, the Smash Childhood Cancer started in January 2017 looking for drug candidates targeting additional childhood cancers.
The Association of Women for Action and Research (AWARE) is a not-for-profit organisation that advocates for gender equality and provides critical support services for women in Singapore. It is a registered charity with Institute of Public Character status.
The Neuroblastoma Children's Cancer Alliance UK, commonly referred to as NCCA UK, is a UK charity that helps children and families affected by neuroblastoma, a type of childhood cancer. The charity helps families by helping them to access and fundraise for their child's treatment abroad when no treatment is available in the UK, offering support and funding research into the condition.
Talia Joy Castellano was an American internet personality and model who was best known for her work on YouTube, notably her makeup and fashion content, and for becoming the first honorary CoverGirl in 2012. She battled the diseases neuroblastoma and leukemia for six years, and died on July 16, 2013. As of May 2021, her YouTube channel has received over a million subscribers.
Dinutuximab and dinutuximab beta are monoclonal antibodies used as a second-line treatment for children with high-risk neuroblastoma. Each antibody is made of both mouse and human components and targets glycolipid GD2, expressed on neuroblastoma cells and on normal cells of neuroectodermal origin, including the central nervous system and peripheral nerves. They differ in that dinutuximab is manufactured using mouse cells, and dinutuximab beta is manufactured using hamster cells. The dosing regime differs, and dinutuximab is given in combination with granulocyte-macrophage colony stimulating factor (GM-CSF), interleukin-2 (IL-2) and 13-cis-retinoic acid (RA), while dinutuximab beta can be given alone.
Islamic teachings on humanity and human welfare have been codified in its central religious book known as the Quran, which the Muslims believe was revealed by God for the humankind. These teachings have often been exemplified by Islamic prophet Muhammad as displayed in his sayings and practices. To the Muslims, Islam is what the Quran has instructed to do and how Muhammad has put them into practice. Thus, the understanding of any Islamic topic generally rely on these two.
Holger Lode is a German specialist for pediatrics. He is Professor and Chair of the Department of General Pediatrics and Pediatric Hematology and Oncology at the University Medicine Greifswald. He is also the director of the Center of Pediatrics and Adolescent Medicine in Greifswald. Lode is well known for his clinical and scientific work on immunotherapy of neuroblastoma.
Naxitamab, sold under the brand name Danyelza, is an anti-cancer medication. It is a monoclonal antibody used in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF) for people one year of age and older with relapsed or refractory high-risk neuroblastoma in the bone or bone marrow demonstrating a partial response, minor response, or stable disease to prior therapy.
John Matthew Maris is an American pediatric oncologist. He is the Giulio D’Angio Endowed Professor of Pediatrics at the Children's Hospital of Philadelphia (CHOP) and Full Professor at the Perelman School of Medicine at the University of Pennsylvania.
