Nicholas Lowe

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Nicholas Lowe
Born (1944-07-10) July 10, 1944 (age 80)
England
Education University of Liverpool
Occupation Dermatologist
Title Clinical Professor of Dermatology

Nicholas J Lowe (born 10 July 1944) is an English dermatologist who has published research into skin pharmacology, botulinum toxins, injectable filler and Lasers in cutaneous and cosmetic Surgery. [1]

Contents

He was president of the British Cosmetic Dermatology Group from 2013 to 2015. [2] He is a clinical professor of dermatology at UCLA School of Medicine, Los Angeles. He is a Fellow of the Royal College of Physicians, American Academy of Dermatology and American Society of Laser Medicine and Surgery. [3]

Education

Lowe graduated from University of Liverpool School of Medicine, [4] England, in 1968. In 1975, he was awarded a Research Fellowship at the Scripps Research Institute where he worked with Professor Richard Stoughton, in skin pharmacology and percutaneous absorption. His doctoral MD research thesis described mechanisms and control of excessive epidermal cell growth.

In 1975, as a professor of dermatology at University of Wisconsin, he performed research on how ultraviolet light damages the skin and contributes to skin cancers. [5] He was subsequently appointed to Professor of Dermatology [6] at David Geffen School of Medicine at UCLA, Los Angeles, California, United States.

Research

In 1980, he founded the largest psoriasis therapy centre in Southern California, the Dermatology Institute and Skin Care Center, [7] where he also conducted some of the first research studies on vitamin A derivatives for psoriasis, acne and other disfiguring skin diseases. He was appointed to the Medical Advisory Board of the National Psoriasis Foundation in the US.[ citation needed ]

In the 1980s, he conducted one of the first clinical research studies in psoriasis a completely new category of drugs for the treatment of psoriasis known as biologic drugs. These were drugs that were capable of targeting immunologic defects in psoriasis; new generations of these biological drugs are now used worldwide as biologic therapy for psoriasis, arthritis and related diseases. [8]

In 1980, he performed research on a category of the first new sunscreens that protected from long wave ultraviolet (or UVA) and UVB. He also confirmed that UVA was responsible for skin aging, skin cancer, unwanted pigmentation and skin sagging and during this research period he also proved the protectiveness of sunscreens against UVA damage in human studies. [9] [10]

In the 1990s, he published research on the use of ultra-pulsed carbon dioxide lasers in dermatology, [11] which were developed and used to reduce skin aging, skin sagging, wrinkling and improve disfiguring scars. [12]

Lowe was the lead investigator in the first placebo control study of Botox for reducing forehead frown lines. At this time neither the dose nor was the safety of Botox was known. Lowe described the how to measure the improvement and using muscle recording electrodes and found the correct muscles to inject Botox. Together with dermatologist Dr Alastair Carruthers, he presented their early studies on the aesthetic use of Botox at the American Academy of Dermatology symposium. [13] He has also shown that Botox injections are an effective way of reducing and controlling the sweating for long periods of time. Pivotal publications on this include a British Medical Journal paper. [14]

Awards

Research Publications and Resources

Dr Lowe has written over 450 clinical and research papers and 19 books, sits on the editorial board of scientific journals and is a founding editor of the Journal of Cutaneous Laser Therapy. [18] [19]

Books for the general public:

Published medical books in chronological order are:

Related Research Articles

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References

  1. ↑ "Meet Dr Nick Lowe". Aesthetics Insider.
  2. ↑ "Dr Nick Lowe joins Aesthetics editorial board". Aesthetics. Retrieved 11 December 2022.
  3. ↑ "Meet Dr Nick Lowe". Aesthetic Medicine.
  4. ↑ "Nicholas Charles LOWE". General Medical Council.
  5. ↑ Lowe, NJ; Stoughton, RB (February 1977). "Essential fatty acid deficient hairless mouse: a model of chronic epidermal hyperproliferation". The British Journal of Dermatology. 96 (2): 155–62. doi:10.1111/j.1365-2133.1977.tb12537.x. PMID   843450. S2CID   2486355.
  6. ↑ "Spotlight on: Nicholas Lowe, MB, ChB, MD, FRCP". The Dermatologist. Dermatology Learning Network.
  7. ↑ "Clinical Science Institute - Dermatology Institute & Skin Care Center". www.discc.com. Retrieved 21 January 2018.
  8. ↑ Lowe, N J (28 March 1987). "Phototherapy and dithranol treatment of psoriasis". BMJ. 294 (6575): 839. doi:10.1136/bmj.294.6575.839. PMC   1245892 . PMID   3105768.
  9. ↑ Sunscreens: Development, Evaluation, and Regulatory Aspects. "M Decker", Google Books .
  10. ↑ Physician's Guide to Sunscreens. "Dekker", Google Books .
  11. ↑ LOWE, NICHOLAS J.; LASK, GARY; GRIFFIN, MOLLY E.; MAXWELL, ANNE; LOWE, PHILIPPA; QUILADA, FLORIZZA (December 1995). "Skin Resurfacing with the Ultrapulse Carbon Dioxide Laser". Dermatologic Surgery. 21 (12): 1025–1029. doi:10.1111/j.1524-4725.1995.tb00552.x. PMID   7496669. S2CID   23913846.
  12. ↑ LOWE, NICHOLAS J.; LASK, GARY; GRIFFIN, MOLLY E. (December 1995). "Laser Skin Resurfacing". Dermatologic Surgery. 21 (12): 1017–1019. doi:10.1111/j.1524-4725.1995.tb00550.x. S2CID   30122352.
  13. ↑ "In 1996 at the annual meeting of The American Academy of Dermatology in Washington, a presentation by dermatologist Dr. Nicholas Lowe showed that BOTOX® was useful for improving facial expression lines". Dermatology Associates of Atlanta. 4 June 2013. Retrieved 8 July 2015.
  14. ↑ Naumann, M; Lowe, N J (15 September 2001). "Botulinum toxin type A in treatment of bilateral primary axillary hyperhidrosis: randomised, parallel group, double blind, placebo controlled". BMJ. 323 (7313): 596–599. doi:10.1136/bmj.323.7313.596. PMC   55572 . PMID   11557704.
  15. ↑ "Dr Nicholas James LOWE". IMCAS.
  16. ↑ "Dr Nicholas James LOWE". IMCAS.
  17. ↑ "Meet Dr Nicck Lowe". Aesthetics Insider.
  18. ↑ P Lask, Nicholas J Lowe, Gary (January 1999). "Editorial". Journal of Cosmetic and Laser Therapy. 1 (1): 1–2. doi:10.1080/14628839950517020.
  19. ↑ Lowe, Nicholas. "Lowe". Research Gate.
  20. ↑ Lowe, Nicholas J. (1993). Managing your psoriasis. New York: MasterMedia. ISBN   978-0942361841.
  21. ↑ Sellar, Nicholas Lowe, Polly (1999). Skin secrets : the medical facts versus the beauty fiction. London: Collins & Brown. ISBN   1855856654.{{cite book}}: CS1 maint: multiple names: authors list (link)
  22. ↑ Lowe, Nick (2005). Away with wrinkles : the essential guide to a younger-looking face. New York: Marlowe & Co. ISBN   1569244588.
  23. ↑ Lowe, Nick (2007). The wrinkle revolution : a top dermatologist's latest secrets (Rev.. ed.). London: Kyle Cathie Ltd. ISBN   978-1856267717.
  24. ↑ Lowe, Nick (10 March 2016). Perfectly Clear. Troubador Publishing. ISBN   978-1785890833.
  25. ↑ Models in Dermatology, Vol. 1. Karger. ISBN   978-3-8055-3945-6.
  26. ↑ Models in Dermatology, Vol. 2. Karger. ISBN   978-3-8055-3947-0.
  27. ↑ Models in Dermatology, Vol. 3. Karger. 1987. ISBN   978-3-8055-4239-5.
  28. ↑ Models in Dermatology, Vol. 4. Karger. 1985. ISBN   978-3-8055-4761-1.
  29. ↑ Nonsteroidal anti-inflammatory drugs. "Karger", Google Books .
  30. ↑ Sunscreens: Development, Evaluation, and Regulatory Aspects. "M Decker", Google Books .
  31. ↑ Physician's Guide to Sunscreens. "Dekker", Google Books .
  32. ↑ Lowe, Nicholas J. Lowe (1993). Practical psoriasis therapy (2nd. ed.). St. Louis: Mosby-Year Book. ISBN   9780801671814.
  33. ↑ Managing Your Psoriasis. "Master Media", Google Books .
  34. ↑ Psoriasis: Retinoids, Second Edition. "Taylor & Francis", Google Books .
  35. ↑ Lowe, Gary P. Lask; Nicholas J. (2000). Lasers in cutaneous and cosmetic surgery (1st ed.). Philadelphia [u.a.]: Churchill Livingstone. ISBN   9780443076398.{{cite book}}: CS1 maint: multiple names: authors list (link)
  36. ↑ al.], Nicholas J. Lowe ... [et (2001). Textbook of facial rejuvenation : the minimally invasive combination approach (Repr. ed.). London: Martin Dunitz. ISBN   9781841840956.
  37. ↑ Botox: Aesthetic Conditions. "Taylor & Francis", Google Books .
  38. ↑ Psoriasis: A Patient's Guide, Third Edition. "Taylor & Francis", Google Books .
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