Nidularium 'Chantrieri'

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Nidularium 'Chantrieri'
Hybrid parentage Nidularium hybrid
innocentii × fulgens
Cultivar 'Chantrieri'
Origin1895

'Chantrieri' is a hybrid cultivar of the genus Nidularium in the Bromeliad family.

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<i>Tacca</i> Genus of flowering plants

The genus Tacca, which includes the batflowers and arrowroot, consists of flowering plants in the order Dioscoreales, native to tropical regions of South America, Africa, Australia, Southeast Asia, and various oceanic islands. In older texts, the genus was treated in its own family Taccaceae, but the 2003 APG II system incorporates it into the family Dioscoreaceae. The APG III and APG IV systems continue to include Tacca in Dioscoreaceae.

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<i>Nidularium innocentii</i> Species of flowering plant

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<i>Tacca chantrieri</i> Species of plant

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Taccalonolide

Taccalonolides are a class of microtubule-stabilizing agents isolated from Tacca chantrieri that has been shown to have selective cancer-fighting properties. Other examples of microtubule-stabilizing agents include taxanes and epothilones, both of which prevent cancer cells from dividing by interfering with tubulin. While taxanes like Paclitaxel and docetaxel have been used successfully against breast, ovarian, prostate, and non–small-cell lung cancers, intrinsic and acquired drug resistance limit their anticancer properties. Unlike taxanes, taccalonolides appear to work through a different mechanism of action that does not involve tubulin, although recently isolated taccalonolides AF and AJ have shown tubulin-interaction activity. The discovery of taccalonolides opens up new possibilities to treat cancer cells, especially ones that are taxane or epithilone resistant.

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