State Route 330 (SR 330) is a north–south state highway in the northwestern portion of the U.S. state of Ohio. The southern terminus of SR 330 is at a diamond interchange with the SR 15 expressway just south of the village limits of Vanlue. Its northern terminus is at SR 568 nearly 1.75 miles (2.82 km) north of Vanlue.
State Route 281 is an east–west state highway in the northwestern portion of the U.S. state of Ohio. Its western terminus is at U.S. Route 24 approximately four miles (6.4 km) northeast of downtown Defiance, and its eastern terminus is at US 6 nearly one mile (1.6 km) north of Bradner. The majority of the route is known as the Defiance Pike.
State Route 300 is a 6.33-mile (10.19 km) long north–south state highway in northwestern Ohio, a U.S. state. The southern terminus of SR 300 is at a T-intersection with U.S. Route 6 (US 6) approximately 1.50 miles (2.41 km) west of the village of Helena. Its northern terminus is at US 20 just over 2.50 miles (4.02 km) southeast of Woodville.
State Route 665 is an east–west state highway located in central Ohio, a U.S. state. The western terminus of this state highway is at a signalized intersection that marks the confluence of US 42, SR 38, SR 56 and SR 142 in downtown London. Its eastern terminus is at an intersection with US 23 and SR 317 approximately 2.50 miles (4.02 km) northwest of the village of Lockbourne.
State Route 26 is a 67-mile-long (108 km) north–south route in south eastern Ohio spanning from SR 7 in Marietta to SR 148 between Jerusalem and Bethesda. SR 26 also passes through Graysville and Woodsfield. Where the state route designation ends in Wayne Township, the road continues north as Belmont County Road 26 where it connects to the Barkcamp State Park and the National Road. Much of the route parallels the Little Muskingum River and travels through the heart of Wayne National Forest's Marietta Unit.
State Route 161 is an east–west state highway in central Ohio. Its western terminus is in Mutual at State Route 29 and its eastern terminus is near Alexandria at State Route 37. It is 57.46 miles (92.47 km) long. State Route 161 passes through the northern parts of Columbus, Ohio's state capital, and a variety of towns including Plain City, Dublin, and New Albany.
State Route 38 is a south–north state highway in the state of Ohio. Its southern terminus is near Bloomingburg and Washington Court House at the U.S. Route 62 / SR 3 concurrency and its northern terminus is in Marysville at the intersection of 5th Street and Main Street where the road continues north as SR 31.
State Route 797 was a very short, unsigned north–south state highway in the eastern portion of the U.S. state of Ohio. At the time of its deletion of the route from the state highway system, SR 797 ran from its southern terminus at the U.S. Route 22/U.S. Route 40 concurrency about 4.75 miles (7.64 km) northeast of Zanesville to its northern terminus less than 0.40 miles (0.64 km) to the northwest at Interstate 70 at its exit 160, a diamond interchange. North of the interchange, the road continues to Sonora on Muskingum County Road 52, Sonora Road.
State Route 317 (SR 317) is a north–south state highway in the central portion of the U.S. state of Ohio. Its southern terminus is at U.S. Route 23 approximately 9 miles (14 km) south of Downtown Columbus and just outside the city limits; its northern terminus is at U.S. Route 62 in Gahanna. The route serves as a partial southeastern outbelt for the Columbus metropolitan area, passing through many commercial districts and light industry areas.
State Route 49 is a state highway in the western part of the U.S. state of Ohio. It begins in Drexel, an area within the city of Trotwood, at US 35 and runs northwesterly to Greenville, and then runs roughly along near the western edge of the state near the Indiana state line to the Michigan state line where it meets with Michigan's M-49.
State Route 96 is an east–west state highway in the northern portion of the U.S. state of Ohio. The southern terminus of SR 96 is at a T-intersection with SR 98 nearly 2+1⁄2 miles (4.0 km) northeast of Bucyrus. Its eastern terminus is at an interchange with US 42 and US 250 in the eastern portion of Ashland.
State Route 79 is a north–south highway that traverses Central Ohio, extending from Buckeye Lake at SR 37 to Nellie at US 36. SR 79 serves Newark, providing direct-access from Downtown Newark to I-70.
State Route 800 is a north–south state highway in the eastern portion of the U.S. state of Ohio. Its southern terminus is at SR 7 in Jackson Township near New Matamoras, and its northern terminus is at its interchange with Interstate 77 in Canton.
State Route 518 is an east–west state highway located entirely in Columbiana County in northeast Ohio. The western terminus of SR 518 is at SR 644 north of Summitville. Its eastern terminus is at the concurrency of U.S. Route 30 (US 30) and SR 45 near West Point.
State Route 152 is the designation for two segments of a state highway in Jefferson County, Ohio. The southern segment, which is 6.18 miles (9.95 km) long, runs from SR 150 in Dillonvale to SR 151 in Smithfield. The northern segment, which is 20.20 miles (32.51 km) long, runs from an interchange with U.S. Route 22 (US 22) in Bloomingdale to SR 7 in Empire.
State Route 320 (SR 320) is a short north–south state highway in western Ohio, a U.S. state. The southern terminus of SR 320 is at U.S. Route 35 (US 35) approximately three miles (4.8 km) southeast of New Paris, 3⁄4 mile (1.2 km) south of US 35's eastern junction with Interstate 70 (I-70). The northern terminus of the state highway is located in New Paris at a signalized intersection with SR 121.
State Route 202 (SR 202) is a 20-mile (32 km) north–south state highway in the western part of the U.S. state of Ohio. The highway runs from its southern terminus at an intersection with SR 201 in Dayton to its northern terminus at a T-intersection with SR 55 in the eastern end of Troy.
State Route 751 is an east–west state highway located in the east-central portion of Ohio. The highway runs between its western terminus at SR 93 in West Lafayette and its eastern terminus at a diamond interchange with I-77 on the outskirts of the village of Stone Creek.
State Route 668 is a north-south state highway in central Ohio. Its southern terminus is at an intersection with SR 93 in the Wayne National Forest, northeast of Logan; its northern terminus is at an intersection with US 40 in the unincorporated community of Brownsville.
US 42 / SR 38 / SR 56 / SR 665 in London 
US 40 in West Jefferson 
I-70 / CR 7 near West Jefferson
