Optellum

Last updated

Optellum
Company typePrivate
IndustryMedical technology
Founded28 October 2015
Founders Prof. Sir Michael Brady, Dr. Václav Potěšil, Dr. Timor Kadir, Dr. Jérôme Declerck, Dr. Lyndsey Pickup
HeadquartersOxford, Oxfordshire, United Kingdom
Key people
Dr. Johnathan Watkins (CEO), Prof. Sir Michael Brady (Founding Chair)
ProductsVirtual Nodule Clinic
Website optellum.com

Optellum is a British medical technology company that develops artificial intelligence (AI)-based clinical decision-support software for early lung cancer diagnosis and the early detection, management, and follow-up of incidental pulmonary nodules. [1] [2]

Contents

History

Optellum was incorporated in October 2015 in the United Kingdom. [3] It originated from research at the University of Oxford's Computer Vision Laboratory, with the goal of applying machine learning to lung-nodule assessment and diagnosis. It was founded by four Oxford scientists and emeritus professor of oncological imaging at the University of Oxford, Sir Michael Brady [4]

In 2022, Optellum raised US$14 million in Series A funding to expand operations in the UK and the United States and to accelerate deployment of their AI platform for lung cancer diagnosis. [1]

Products and technology

Optellum's core platform, the Virtual Nodule Clinic, assists radiologists and pulmonologists in identifying and evaluating lung nodules. [2] The software uses radiomics and machine learning algorithms to compute a Lung Cancer Prediction (LCP) score that estimates malignancy risk. [5] [6] The system also supports screening and management of incidental nodules, detecting high-risk nodules in CT scans performed for other clinical reasons such as emergency or cardiac evaluations, and enabling longitudinal tracking and follow-up of these patients. [2]

The Virtual Nodule Clinic has received regulatory clearances in several jurisdictions, including U.S. FDA 510(k), CE Mark, and UKCA approval. [1] It is associated with CPT® code 0721T for AI-based lung nodule risk assessment and management. In 2022, the U.S. Centers for Medicare & Medicaid Services (CMS) approved a national payment rate for the LCP score, enabling Medicare reimbursement. [2] The platform has been deployed in healthcare systems such as AtlantiCare in New Jersey, which reported identifying multiple high-risk nodules through its use. [7]

Partnerships

In 2025, Optellum announced a collaboration with Bristol-Myers Squibb to implement its AI system across several U.S. healthcare networks to improve early lung cancer diagnosis. [8] It has also partnered with GE HealthCare to expand AI integration into imaging and lung health solutions. [9]

See also

References

  1. 1 2 3 "Oxford spinout Optellum secures $14m funding to advance pioneering AI-powered lung cancer diagnosis technology". University of Oxford (Press release). 3 October 2022. Retrieved 9 November 2025.
  2. 1 2 3 4 "Optellum's Virtual Nodule Clinic: A trailblazing AI for early lung cancer diagnosis". Oxford Academic Health Partners. 10 May 2024. Retrieved 9 November 2025.
  3. "OPTELLUM LTD overview". Companies House. Retrieved 9 November 2025.
  4. R., Vignesh (3 October 2022). "Founded by four scientists in Oxford, Optellum raises $14M for its AI-powered lung cancer diagnosis". Tech Funding News. Retrieved 9 November 2025.
  5. Paez, Rafael; Kammer, Michael N.; Balar, Aneri; Lakhani, Dhairya A.; Knight, Michael; Rowe, Dianna; Xiao, David; Heideman, Brent E.; Antic, Sanja L.; Chen, Heidi; Chen, Sheau-Chiann; Peikert, Tobias; Sandler, Kim L.; Landman, Bennett A.; Deppen, Stephen A. (15 April 2023). "Longitudinal lung cancer prediction convolutional neural network model improves the classification of indeterminate pulmonary nodules". Scientific Reports. 13 (1): 6157. Bibcode:2023NatSR..13.6157P. doi:10.1038/s41598-023-33098-y. ISSN   2045-2322. PMC   10105767 . PMID   37061539.
  6. Xiao, David; Forero, Yency; Kammer, Michael N.; Chen, Heidi; Paez, Rafael; Heideman, Brent E.; Owoseeni, Oreoluwa; Johnson, Ian; Deppen, Stephen A.; Grogan, Eric L.; Maldonado, Fabien (27 June 2025). "Radiomic 'Stress Test': exploration of a deep learning radiomic model in a high-risk prospective lung nodule cohort". BMJ Open Respiratory Research. 12 (1) e002687. doi:10.1136/bmjresp-2024-002687. ISSN   2052-4439. PMC   12207176 . PMID   40579208.
  7. "AtlantiCare deploys Optellum AI for early lung cancer diagnosis and treatment". AtlantiCare (Press release). Egg Harbor Township, New Jersey. 23 February 2023. Retrieved 9 November 2025.
  8. "Optellum, Bristol Myers Squibb to Leverage AI to Boost Early Lung Cancer Diagnosis". Imaging Technology News. 17 April 2025. Retrieved 15 November 2025.
  9. Park, Andrea (29 November 2021). "GE HealthCare doubles down on AI with new product launches, partnerships with Optellum and Cambridge". Fierce Biotech. Retrieved 9 November 2025.