Orthodromic

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An orthodromic impulse runs along an axon in its anterograde direction, away from the soma (cell body). [1]

In the heart, orthodromic may also refer to an impulse going from the atria to the ventricles through the AV node, in contrast to some impulses in re-entry that go from the atria to the ventricles through an anomalous accessory pathway (antidromic conduction through de AV node). This is relevant in the differential diagnosis of supraventricular tachycardia, mainly AV re-entrant tachycardia. [2]

See also

References

  1. EYZAGUIRRE, C; KUFFLER, SW (Sep 20, 1955). "Further study of soma, dendrite, and axon excitation in single neurons". The Journal of General Physiology. 39 (1): 121–53. doi:10.1085/jgp.39.1.121. PMC   2147522 . PMID   13252238.
  2. Katritsis, Demosthenes G; Morady, Fred (2022), "Wolff-Parkinson-White syndrome and atrioventricular reentrant tachycardias", Clinical Cardiac Electrophysiology, Elsevier, pp. 276–305.e1, doi:10.1016/b978-0-323-79338-4.00024-8, ISBN   978-0-323-79338-4 , retrieved 2025-08-27