Sanchez, a native New Yorker, was raised by his mother, Violeta Zoila Carbajal, in Jackson Heights, Queens. He was the youngest of two boys and two girls.
Otto's passion for painting was his first connection into the arts. After pursuing Advertising Design at the Fashion Institute of Technology in New York City, 1987 to 1989, then fine arts at the Columbus College of Art and Design, in Columbus, Ohio, on a scholarship, his passion shifted into theater. Returning to New York City in 1991, he studied acting under Jeanne Kaplan and Austin Pendleton at HB Studio. In 1998, he landed his breakthrough role Carmen "Chico" Guerra on the HBO series Oz.
"In one of the play's sharpest moments a waiter played by Otto Sanchez earnestly tells Stephen about his hard-luck American life, and you can see Stephen (John Gallagher, Jr.) translating it into a stump-speech anecdote in his head." — Ben Brantley, NY Times.
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