Discipline | Pathology |
---|---|
Language | Italian, English |
Publication details | |
Publication history | Founded 1908 |
Publisher | Società Anatomo Patologi Ospedalieri Italiani (Italy) |
Frequency | Bimonthly |
Standard abbreviations | |
Pathologica | |
Indexing | |
ISSN | 0031-2983 (print) 1591-951X (web) |
OCLC no. | 1681013 |
Pathologica is an academic journal which covers the field of general and human pathology, including studies of pathological processes using immunocytochemistry and molecular biology. [1] Founded in 1908, it was published on behalf of the Società Anatomo Patologi Ospedalieri Italiani by Springer-Verlag Milan until 2003, and is now published for the society by Ospedali Galliera di Genova. [2] [3] [4] Pathologica is published bimonthly in Italian, with some recent content in English, and is indexed by Medline. [2]
An academic or scholarly journal is a periodical publication in which scholarship relating to a particular academic discipline is published. Academic journals serve as permanent and transparent forums for the presentation, scrutiny, and discussion of research. They are usually peer-reviewed or refereed. Content typically takes the form of articles presenting original research, review articles, and book reviews. The purpose of an academic journal, according to Henry Oldenburg, is to give researchers a venue to "impart their knowledge to one another, and contribute what they can to the Grand design of improving natural knowledge, and perfecting all Philosophical Arts, and Sciences."
Pathology is the study of the causes and effects of disease or injury. The word pathology also refers to the study of disease in general, incorporating a wide range of bioscience research fields and medical practices. However, when used in the context of modern medical treatment, the term is often used in a more narrow fashion to refer to processes and tests which fall within the contemporary medical field of "general pathology," an area which includes a number of distinct but inter-related medical specialties that diagnose disease, mostly through analysis of tissue, cell, and body fluid samples. Idiomatically, "a pathology" may also refer to the predicted or actual progression of particular diseases, and the affix path is sometimes used to indicate a state of disease in cases of both physical ailment and psychological conditions. A physician practicing pathology is called a pathologist.
Immunocytochemistry (ICC) is a common laboratory technique that is used to anatomically visualize the localization of a specific protein or antigen in cells by use of a specific primary antibody that binds to it. The primary antibody allows visualization of the protein under a fluorescence microscope when it is bound by a secondary antibody that has a conjugated fluorophore. ICC allows researchers to evaluate whether or not cells in a particular sample express the antigen in question. In cases where an immunopositive signal is found, ICC also allows researchers to determine which sub-cellular compartments are expressing the antigen.
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