Peter Fedichev

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Peter Fedichev
Born
Peter Olegovich Fedichev
Alma materMoscow Institute of Physics and Technology (M.S.); University of Amsterdam (Ph.D.)
OccupationsPhysicist, biotechnologist, entrepreneur
Known forResearch on quantitative models of ageing; co-founding Gero.ai
Scientific career
InstitutionsGero.ai

Peter Fedichev is a physicist and biotechnologist. He worked on ultracold quantum systems before moving into computational drug design and later longevity research. [1] [2]

Contents

He is the co-founder and chief executive officer of Gero.ai, a biotechnology company based in Singapore that applies physics-based and machine-learning methods to ageing and disease research. [3] [4]

Education and early career

Fedichev received an M.Sc. in theoretical physics from the Moscow Institute of Physics and Technology while conducting research at the Kurchatov Institute. [5] In 1994 he joined the University of Amsterdam and the AMOLF institute, completing a Ph.D. cum laude in theoretical physics. He later worked at the University of Innsbruck on condensed-matter and quantum-gas systems. [6] [7] [8]

Research

During the 2000s Fedichev co-founded Quantum Pharmaceuticals, an early company exploring computational drug design. [9] Since 2015 he has led Gero.ai, whose studies use large health datasets and mathematical models to analyse ageing dynamics. [10] [2] In a 2021 study published in Nature Communications , Fedichev and co‑authors analysed longitudinal blood biomarker data and step‑count records to propose that human resilience declines with age and may limit maximum lifespan. [11] [12] Scientific American cited him noting that the convergence of blood and activity data suggests a “real pace-of-aging factor”. [2]

Fedichev has written on the use of physical and mathematical approaches to describe biological ageing. He and co-authors have proposed that the progression of ageing can be treated as a problem in non-equilibrium thermodynamics and complex-systems dynamics. Fedichev and collaborators have published models describing how variability in health indicators increases with age and may predict lifespan limits. [13] [14] Subsequent studies extended this framework to distinguish between processes that might be reversible through intervention and those that appear thermodynamically irreversible. [15] [16] Nature gathered these developments in its 2024 “Gerophysics” article collection, co-edited by Fedichev and biologist Brian K. Kennedy, describing the field as an emerging interdisciplinary area linking statistical physics and biogerontology. [17] [3]

Gero

Gero.ai, co-founded in 2018 by Fedichev and Maxim Kholin in Singapore, develops physics-informed AI models trained on electronic medical records and molecular-level data to predict health trajectories and identify potential therapeutic targets for ageing-related conditions. [3] [4] [18] In January 2023 Gero entered a research collaboration with Pfizer to identify therapeutic targets for fibrotic diseases. [19] In July 2025 Gero signed a joint research and licence agreement with Chugai Pharmaceutical (a member of the Roche Group) to develop antibody therapies against targets identified by its AI models. [20]

Selected publications

References

  1. "Humans Can Stop—But Not Fully Reverse—Aging, Study Suggests". Popular Mechanics. 4 April 2023. Retrieved 16 December 2025.
  2. 1 2 3 Willingham, Emily (1 August 2021). "Humans Could Live up to 150 Years, New Research Suggests". Scientific American. Retrieved 16 December 2025.
  3. 1 2 3 Lomas, Natasha (7 May 2021). "Longevity startup Gero AI has a mobile API for quantifying health changes". TechCrunch. Retrieved 16 December 2025.
  4. 1 2 "Стартап выходцев из России Gero привлек $6 млн на поиск методов борьбы со старением". Forbes.ru (in Russian). Archived from the original on 5 August 2025. Retrieved 16 December 2025.
  5. "Пётр Федичев — все книги и биография автора в интернет-магазине «Альпина Паблишер»". alpinabook.ru (in Russian). Retrieved 16 December 2025.
  6. Schweikhard, V.; Coddington, I.; Engels, P.; Mogendorff, V. P.; Cornell, E. A. (29 January 2004). "Rapidly Rotating Bose-Einstein Condensates in and near the Lowest Landau Level". Physical Review Letters. 92 (4) 040404. arXiv: cond-mat/0308582 . doi:10.1103/physrevlett.92.040404. ISSN   0031-9007. PMID   14995357. Archived from the original on 1 April 2025.
  7. Mazin, Arkadi. "Peter Fedichev Explains His Theory of Aging | Lifespan Research Institute". www.lifespan.io. Retrieved 16 December 2025.
  8. "Петр Федичев. Старение как болезнь: возможно ли вылечить старость? Полная версия". tvrain.tv. 9 April 2012. Retrieved 16 December 2025.
  9. "Russia's Bet on Biopharma | PharmExec". www.pharmexec.com. 16 December 2025. Retrieved 16 December 2025.
  10. Podolskiy, D.; Molodtcov, I.; Zenin, A.; Kogan, V.; Menshikov, L. I.; Gladyshev, Vadim N.; Reis, Robert J. Shmookler; Fedichev, P. O. (23 November 2016), Critical dynamics of gene networks is a mechanism behind ageing and Gompertz law, arXiv: 1502.04307
  11. Tarkhov, Andrei E.; Menshikov, Leonid I.; Fedichev, Peter O. (7 March 2017). "Strehler-Mildvan correlation is a degenerate manifold of Gompertz fit". Journal of Theoretical Biology. 416: 180–189. doi: 10.1016/j.jtbi.2017.01.017 . ISSN   0022-5193. PMID   28093294.
  12. Pyrkov, Timothy V.; Slipensky, Konstantin; Barg, Mikhail; Kondrashin, Alexey; Zhurov, Boris; Zenin, Alexander; Pyatnitskiy, Mikhail; Menshikov, Leonid; Markov, Sergei; Fedichev, Peter O. (26 March 2018). "Extracting biological age from biomedical data via deep learning: too much of a good thing?". Scientific Reports. 8 (1): 5210. doi:10.1038/s41598-018-23534-9. ISSN   2045-2322. PMC   5980076 . PMID   29581467.
  13. Nature Communications – Longitudinal analysis of blood markers
  14. "About the Guest Editors | Gerophysics". www.nature.com. Retrieved 16 December 2025.
  15. Tarkhov, Andrei E.; Denisov, Kirill A.; Fedichev, Peter O. (11 October 2022). "Aging clocks, entropy, and the limits of age-reversal". bioRxiv   10.1101/2022.02.06.479300 .
  16. Perevoshchikova, Kristina; Fedichev, Peter O. (28 February 2024). "Differential Responses of Dynamic and Entropic Aging Factors to Longevity Interventions". bioRxiv   10.1101/2024.02.25.581928 .
  17. "Gerophysics". Nature. 3 March 2026. Retrieved 16 December 2025.
  18. Мамедов, Джейхун. "Российские инженеры одними из первых начали борьбу со старением человека. Получится ли у них обойти более «поздних» американцев, но с миллионами долларов инвестиций? История Gero". Инк. (in Russian). Retrieved 16 December 2025.
  19. Pfizer press release – Longevity Biotech Gero Entered Research Collaboration with Pfizer
  20. "Roche's Chugai Breaks Into Aging via Potential $1B+ Deal With AI Outfit Gero". BioSpace. 7 July 2025. Retrieved 16 December 2025.