Phoriospongin A and B are Australian sea sponge isolates with nematocidal activity. They are depsipeptides and were obtained from Phoriospongia species and Callyspongia bilamellata. [1]
A depsipeptide is a peptide in which one or more of its amide, -C(O)NHR-, groups are replaced by the corresponding ester, -C(O)OR, Many depsipeptides have both peptide and ester linkages. They are mainly found in marine and microbial natural products.
Sponges, the members of the phylum Porifera, are a basal Metazoa (animal) clade as a sister of the Diploblasts. They are multicellular organisms that have bodies full of pores and channels allowing water to circulate through them, consisting of jelly-like mesohyl sandwiched between two thin layers of cells. The branch of zoology that studies sponges is known as spongiology.
Cryptophycins are a family of macrolide molecules that are potent cytotoxins and have been studied for potential antiproliferative properties useful in developing chemotherapy. They are members of the depsipeptide family.
Doriprismatica sedna is a species of colorful sea slug, a dorid nudibranch, a marine gastropod mollusk in the family Chromodorididae.
Onchidoris bilamellata, common name the rough-mantled doris, is a species of sea slug, a dorid nudibranch, a shell-less marine gastropod mollusk in the family Onchidorididae.
Callyspongia vaginalis, known as the branching vase sponge is a demosponge.
Callystatin A is a polyketide natural product from the leptomycin family of antibiotics. It was first isolated in 1997 from the marine sponge Callyspongia truncata which was collected from the Goto Islands in the Nagasaki Prefecture of Japan by the Kobayashi group. Since then its absolute configuration has been elucidated and callystatin A was discovered to have anti-fungal and anti-tumor activities with extreme potency against the human epidermoid carcinoma KB cells (IG50 = 10 pg/ml) and the mouse lymphocytic leukemia Ll210 cells (IG50 = 20 pg/ml).
Papuamides A and B are depsipeptides which appear to protect T cells from HIV. They were isolated from the sponge Theonella, and are part of a larger group of structurally similar depsipeptides—also isolated from sponges—including neamphamide A, callipeltin A, and mirabamides A-D.
Cadlina rumia is a species of sea slug or dorid nudibranch, a marine gastropod mollusk in the family Cadlinidae.
Umimayanthus parasiticus, commonly known as the sponge zoanthid, is a species of coral in the order Zoantharia which grows symbiotically on several species of sponge. It is found in shallow waters in the Caribbean Sea and the Gulf of Mexico.
Callyspongia is a genus of demosponges in the family Callyspongiidae.
Callyspongia truncata is a species of demosponge in the family Callyspongiidae.
Neamphamide A is an HIV-inhibitory isolate of the sea sponge Neamphius huxleyi.
Mirabamides are sea sponge isolates that inhibit HIV-1 fusion.
Callyspongia siphonella, commonly known as colonial tube-sponge, is a species of sponge endemic to the Red Sea. Clusters of its pale lavender long tubes reaches up to 60 centimetres (24 in) in size.
Dysidea arenaria is a species of marine sponge (poriferan) found in the Pacific Ocean. It is a member of the order Dictyoceratida, one of two sponge orders that make up the keratose or "horny" sponges in which a mineral skeleton is absent and a skeleton of organic fibers is present instead.
Jorunna spongiosa is a species of sea slug, a dorid nudibranch, a shell-less marine gastropod mollusc in the family Discodorididae.
Callyspongia plicifera, the azure vase sponge, is a species of demosponges belonging to the Callyspongiidae family. It is native to The Bahamas where it is found at a depth of 31.5-44.2 m. It was first described in 1814 by Jean-Baptiste Lamarck.
Callyspongia (Callyspongia) elegans is a species of demosponge in the genus Callyspongia. It is the senior homonym of Callyspongia elegans(Thiele, 1899).
Callyspongia serpentina is a species of demosponges in the family Callyspongiidae. It is found in Australia and New Zealand.
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