Prokaryotic phospholipase A2

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Prokaryotic phospholipase A2
PDB 1kp4 EBI.jpg
Structure of prokaryotic phospholipase A2. [1]
Identifiers
SymbolPhospholip_A2_3
Pfam PF09056
InterPro IPR015141
OPM superfamily 82
OPM protein 1kp4
Available protein structures:
Pfam   structures / ECOD  
PDB RCSB PDB; PDBe; PDBj
PDBsum structure summary

The prokaryotic phospholipase A2 domain is found in bacterial and fungal phospholipases. It enables the liberation of fatty acids and lysophospholipid by hydrolyzing the 2-ester bond of 1,2-diacyl-3-sn-phosphoglycerides. The domain adopts an alpha-helical secondary structure, consisting of five alpha-helices and two helical segments. [2]

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References

  1. ↑ Matoba Y, Katsube Y, Sugiyama M (May 2002). "The crystal structure of prokaryotic phospholipase A2". J. Biol. Chem. 277 (22): 20059–69. doi: 10.1074/jbc.M200263200 . PMID   11897785.
  2. ↑ Katsube Y, Sugiyama M, Matoba Y (2002). "The crystal structure of prokaryotic phospholipase A2". J. Biol. Chem. 277 (22): 20059–69. doi: 10.1074/jbc.M200263200 . PMID   11897785.
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