Pumiliotoxins (PTXs), are one of several toxins found in the skin of poison dart frogs. The frog species, P. bibronii also produces PTXs to deter predators. Closely related, though more toxic, are allopumiliotoxins, (aPTXs). Other toxins found in the skin of poison frogs include decahydroquinolines (DHQs), izidines, coccinellines, and spiropyrrolizidine alkaloids. Pumiliotoxins are very poisonous in high concentrations. Pumiliotoxins are much weaker than batrachotoxins, ranging between 100 and 1000 times less poisonous. There are three different types of this toxin: A, B and C, of which toxins A and B are more toxic than C. Pumiliotoxins interfere with muscle contraction by affecting calcium channels, causing partial paralysis, difficulty moving, hyperactivity, [1] or death. The median lethal dose of pumiliotoxins A and B is 50 μg / mouse, 20 μg / mouse respectively, while the amount of pumiliotoxin is 200 μg / frog. [2]
The hooded pitohui is a species of bird in the genus Pitohui found in New Guinea. It was long thought to be a whistler (Pachycephalidae) but is now known to be in the Old World oriole family (Oriolidae). Within the oriole family, this species is most closely related to the variable pitohuis in the genus Pitohui, and then the figbirds.
Poison dart frog is the common name of a group of frogs in the family Dendrobatidae which are native to tropical Central and South America. These species are diurnal and often have brightly colored bodies. This bright coloration is correlated with the toxicity of the species, making them aposematic. Some species of the family Dendrobatidae exhibit extremely bright coloration along with high toxicity — a feature derived from their diet of ants, mites and termites— while species which eat a much larger variety of prey have cryptic coloration with minimal to no amount of observed toxicity. Many species of this family are threatened due to human infrastructure encroaching on their habitats.
Batrachotoxin (BTX) is an extremely potent cardiotoxic and neurotoxic steroidal alkaloid found in certain species of beetles, birds, and frogs. The name is from the Greek word βάτραχος, bátrachos, 'frog'. Structurally-related chemical compounds are often referred to collectively as batrachotoxins. In certain frogs, this alkaloid is present mostly on the skin. Such frogs are among those used for poisoning darts. Batrachotoxin binds to and irreversibly opens the sodium channels of nerve cells and prevents them from closing, resulting in paralysis and death. No antidote is known.
The blue poison dart frog or blue poison arrow frog is a poison dart frog found in the "forest islands" surrounded by the Sipaliwini Savanna in southern Suriname and northern Pará (Brazil). Its indigenous Tirio name is okopipi. The name "azureus" comes from its azure blue color. While first described as a valid species and usually recognized as such in the past, recent authorities generally treat it as a morph of D. tinctorius, although a few treat it as a subspecies of D. tinctorius or continue to treat it as its own species. To what extent it differs from the blue D. tinctorius in southern Guyana, adjacent Pará (Brazil) and possibly far southwestern Suriname, is also a matter of dispute, and many herpetologists, as well as many people keeping poison dart frogs in captivity, have not distinguished these, with all commonly being identified as azureus.
Epibatidine is a chlorinated alkaloid that is secreted by the Ecuadoran frog Epipedobates anthonyi and poison dart frogs from the Ameerega genus. It was discovered by John W. Daly in 1974, but its structure was not fully elucidated until 1992. Whether epibatidine is the first observed example of a chlorinated alkaloid remains controversial, due to challenges in conclusively identifying the compound from the limited samples collected by Daly. By the time that high-resolution spectrometry was used in 1991, there remained less than one milligram of extract from Daly's samples, raising concerns about possible contamination. Samples from other batches of the same species of frog failed to yield epibatidine.
The strawberry poison frog, strawberry poison-dart frog or blue jeans poison frog is a species of small poison dart frog found in Central America. It is common throughout its range, which extends from eastern central Nicaragua through Costa Rica and northwestern Panamá. The species is often found in humid lowlands and premontane forest, but large populations are also found in disturbed areas such as plantations. The strawberry poison frog is perhaps most famous for its widespread variation in coloration, comprising approximately 15–30 color morphs, most of which are presumed to be true-breeding. O. pumilio, while not the most poisonous of the dendrobatids, is the most toxic member of its genus.
The dyeing poison dart frog, also known as the cobalt poison frog, tinc, or dyeing poison frog, is a species of poison dart frog. It is among the most variably colored and largest species of poison dart frogs, typically reaching snout–vent lengths of about 50 mm (2.0 in). It is distributed in the eastern portion of the Guiana Shield, including parts of French Guiana, Guyana, Suriname and Brazil.
The golden poison frog, also known as the golden dart frog or golden poison arrow frog, is a poison dart frog endemic from the rainforests of Colombia. The golden poison frog has become endangered due to habitat destruction within its naturally limited range. Despite its small size, this frog is considered to be the most poisonous extant animal species on the planet.
PTX may refer to:
Phyllobates is a genus of poison dart frogs native to Central and South America, from Nicaragua to Colombia. There are 3 different Colombian species of Phyllobates, considered highly toxic species due to the poison they contain in the wild.
Phyllobates aurotaenia is a member of the frog family Dendrobatidae, which are found in the tropical environments of Central and South America. First described by zoologist George Albert Boulenger in 1913, P. aurotaenia is known for being the third most poisonous frog in the world. It is the smallest of the poison dart frogs in the Phyllobates genus and is endemic to the Pacific coast of Colombia.
Lehmann's poison frog or the red-banded poison frog is a species of frogs in the family Dendrobatidae endemic to a small part of western Colombia. Its natural habitats are submontane tropical rainforests. It is threatened by habitat loss and collection for the pet trade, and the IUCN lists it as being "critically endangered". It was named after Colombian conservation biologist Federico Carlos Lehmann.
Oophaga sylvatica, sometimes known as its Spanish name diablito, is a species of frog in the family Dendrobatidae found in Southwestern Colombia and Northwestern Ecuador. Its natural habitat is lowland and submontane rainforest; it can, however, survive in moderately degraded areas, at least in the more humid parts of its range. It is a very common frog in Colombia, but has disappeared from much of its Ecuadorian range. It is threatened by habitat loss (deforestation) and agricultural pollution and sometimes seen in the international pet trade.
Pumiliotoxin 251D is a toxic organic compound. It is found in the skin of poison frogs from the genera Dendrobates, Epipedobates, Minyobates, and Phyllobates and toads from the genus Melanophryniscus. Its name comes from the pumiliotoxin family (PTXs) and its molecular mass of 251 daltons. When the toxin enters the bloodstream through cuts in the skin or by ingestion, it can cause hyperactivity, convulsions, cardiac arrest and ultimately death. It is especially toxic to arthropods, even at low concentrations.
Allopumiliotoxin 267A is a toxin found in the skin of several poison frogs of the family Dendrobates. It is a member of the class of compounds known as allopumiliotoxins. The frogs produce the toxin by modifying the original version, pumiliotoxin 251D. It has been tested on mice and found to be five times more potent than the former version. It has been produced synthetically through a variety of different routes.
Allopumiliotoxins are a structural division in the pumiliotoxin-A class of alkaloids. The compounds of the pumiliotoxin-A class are primarily found in the skins of frogs, toads, and other amphibians and are used as a chemical defense mechanism to ward off predators, microorganisms, and ectoparasites. The compounds were originally discovered in neotropical dendrobatid frogs, but are also found in the mantellid frogs of Madagascar, myobatrachid frogs of Australia, and bufonid toad of South America. Frogs possessing this defense mechanism have aposematic coloring.
Adelphobates is a small genus of poison dart frogs. They are found in the central and lower Amazon basin of Peru and Brazil, possibly Bolivia. It was originally erected as a sister group to the Dendrobates and Oophaga genera. The validity of the genus is still being discussed, with the alternative being "Dendrobates galactonotus group" within Dendrobates. One species originally placed in this genus as Adelphobates captivus has since been moved to the genus Excidobates erected in 2008.
Poisonous amphibians are amphibians that produce toxins to defend themselves from predators.
Phyllobates sp. aff. aurotaenia is a temporary name given to a likely new species of poison dart frog, formerly known as the "red" form of Phyllobates aurotaenia. It is morphologically similar to P. aurotaenia, but genetically it is more closely related to P. terribilis. It can be distinguished from P. aurotaenia by its uniform black or bluish-black body, and its orange or red, rather than green or yellow, stripes.
Ranitomeya sirensis or the Sira poison frog is a species of poison dart frog found in the Amazonian rainforests of northern Bolivia, westernmost Brazil (Acre), and eastern Peru.