Ralph H. Hruban

Last updated

Ralph H. Hruban is professor of pathology and oncology at the Johns Hopkins School of Medicine. He is currently Director of the Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins, and Baxley Professor and Director of the Department of Pathology. He is a world expert on pancreatic cancer.

Contents

Education

Hruban attended the University of Chicago Laboratory Schools, graduating from the High School in 1977. [1] He received his undergraduate degree from the University of Chicago in 1981, and his Doctor of Medicine from Johns Hopkins School of Medicine in 1985. He completed his pathology residency at Johns Hopkins, and then spent one year as a fellow at the Memorial Sloan Kettering Cancer Center in New York City. [2]

Career

In 1990, Hruban returned to Johns Hopkins. [2]

Hruban is an expert in the field of pancreatic cancer pathology. [3] He has researched the characterization of PanINs, the precursor lesions that give rise to invasive pancreatic cancer. [4]

Hruban founded the National Familial Pancreas Tumor Registry at Johns Hopkins, which serves as a resource to patients and their families. [2]

Hruban was Director of Science for the Lustgarten Foundation for Pancreatic Cancer Research, and Chair of the advisory committee for the Alan Mason Chesney Medical Archives, the official repository of Johns Hopkins University. [2]

He was also involved in the large-scale project of creating world's first virtually complete draft map of human proteome led by the Institute of Bioinformatics, Bangalore, India and the Johns Hopkins University. [5]

Recognition

He has authored more than 800 peer-reviewed manuscripts and eight books, including the standard textbook on pancreatic pathology (the AFIP Fascicle on Tumors of the Pancreas) and the World Health Organization “blue book” on tumors of the digestive tract. He is recognized by the Institute for Scientific Information as a highly cited researcher and by Essential Science Indicators as the most highly cited pancreatic cancer scientist. [6]

Hruban has received numerous awards including the Arthur Purdy Stout Prize for significant career achievements in surgical pathology, the Ramzi Cotran Award from the United States and Canadian Academy of Pathology, the PanCAN Medical Visionary Award, the Ranice W. Crosby Distinguished Achievement Award in Art as Applied to Medicine, the Ruth C. Brufsky Award of Excellence in Clinical Research for Pancreatic Cancer, the Frank Netter Award for Special Contributions to Medical Education, the Johns Hopkins University Distinguished Alumni Award, the Team Science Award from the American Association for Cancer Research, and five teaching awards from the Johns Hopkins School of Medicine. He was elected to the German National Academy of Sciences Leopoldina in 2013. Hruban also received the Young Investigator Award from the United States and Canadian Academy of Pathology, and the Medical Visionary Award from the Pancreatic Cancer Action Network. [2] In November 2018, Expertscape recognized him as one of the world's foremost experts in pancreatic cancer. [7]

He also produced an award winning documentary on the life of William Stewart Halsted, the founding head of surgery at Johns Hopkins. [8]

Related Research Articles

<span class="mw-page-title-main">Pancreatic cancer</span> Type of endocrine gland cancer

Pancreatic cancer arises when cells in the pancreas, a glandular organ behind the stomach, begin to multiply out of control and form a mass. These cancerous cells have the ability to invade other parts of the body. A number of types of pancreatic cancer are known.

<span class="mw-page-title-main">Johns Hopkins School of Medicine</span> Medical school of Johns Hopkins University

The Johns Hopkins University School of Medicine (JHUSOM) is the medical school of Johns Hopkins University, a private research university in Baltimore, Maryland. Founded in 1893, the School of Medicine shares a campus with Johns Hopkins Hospital and Johns Hopkins Children's Center, established in 1889.

<span class="mw-page-title-main">Bert Vogelstein</span> American oncologist (born 1949)

Bert Vogelstein is director of the Ludwig Center, Clayton Professor of Oncology and Pathology and a Howard Hughes Medical Institute investigator at The Johns Hopkins Medical School and Sidney Kimmel Comprehensive Cancer Center. A pioneer in the field of cancer genomics, his studies on colorectal cancers revealed that they result from the sequential accumulation of mutations in oncogenes and tumor suppressor genes. These studies now form the paradigm for modern cancer research and provided the basis for the notion of the somatic evolution of cancer.

<span class="mw-page-title-main">Steven Rosenberg</span> American cancer researcher

Steven A. Rosenberg is an American cancer researcher and surgeon, chief of Surgery at the National Cancer Institute in Bethesda, Maryland and a Professor of Surgery at the Uniformed Services University of Health Sciences and the George Washington University School of Medicine and Health Sciences. He pioneered the development of immunotherapy that has resulted in the first effective immunotherapies and the development of gene therapy. He is the first researcher to successfully insert foreign genes into humans.

James Lewis Abbruzzese is the Chief of the Duke Division of Medical Oncology and associate director for Clinical Research for the Duke Cancer Institute. Previously, Abbruzzese was Chairman of the Department of Gastrointestinal Medical Oncology at the University of Texas M. D. Anderson Cancer Center where he held the M. G. and Lillie A. Johnson Chair for Cancer Treatment and Research and the Annie Laurie Howard Research Distinguished Professorship. Abbruzzese is one of the world's leaders in the clinical study and treatment of pancreatic cancer.

Markus Wolfgang Büchler is a German surgeon and university full professor. He specialises in gastrointestinal, hepatobiliary and transplant surgery, and is especially known for pioneering operations on the pancreas.

<span class="mw-page-title-main">Eugene Lindsay Opie</span>

Eugene Lindsay Opie was an American physician and pathologist who conducted research on the causes, transmission, and diagnosis of tuberculosis and on immunization against the disease. He served as professor of pathology at several U.S. medical schools and as Dean of the Washington University School of Medicine.

<span class="mw-page-title-main">Intraductal papillary mucinous neoplasm</span> Medical condition

Intraductal papillary mucinous neoplasm (IPMN) is a type of tumor that can occur within the cells of the pancreatic duct. IPMN tumors produce mucus, and this mucus can form pancreatic cysts. Although intraductal papillary mucinous neoplasms are benign tumors, they can progress to pancreatic cancer. As such IPMN is viewed as a precancerous condition. Once an intraductal papillary mucinous neoplasm has been found, the management options include close monitoring and pre-emptive surgery.

<span class="mw-page-title-main">University of Utah School of Medicine</span> Medical school of the University of Utah

The University of Utah School of Medicine is located on the upper campus of the University of Utah in Salt Lake City, Utah. It was founded in 1905 and is currently the only MD-granting medical school in the state of Utah.

Alan L. Schiller is an American clinical pathologist and an expert in the effects of space and weightlessness on bone structure. Schiller has served on the Space Science Board of the Committee on Space Biology and Medicine of the National Academy of Sciences and as a member of the Life and Microgravity Sciences and Applications Advisory Committee of NASA. He currently serves on the board of directors of the National Space Biomedical Research Institute.

<span class="mw-page-title-main">Mark Atkinson (scientist)</span> American medical researcher (born 1961)

Mark Atkinson is an American medical researcher best known for his contributions to research seeking to predict, prevent, and cure type 1 diabetes. He is the author of over 600 publications and is one of the world's most cited diabetes researchers.

<span class="mw-page-title-main">Pancreatic tumor</span> Medical condition

A pancreatic tumor is an abnormal growth in the pancreas. In adults, almost 90% are pancreatic cancer and a few are benign. Pancreatic tumors are rare in children.

David Arthur Tuveson is an American cancer biologist and is currently Roy J. Zuckerberg Professor of Cancer Research as well as The Cancer Center Director at Cold Spring Harbor Laboratory. Dr. Tuveson is also the Chief Scientist for the Lustgarten Foundation for Pancreatic Cancer Research. He is known for developing some of the first mouse models of pancreatic cancer and more recently, for his work developing pancreatic cancer organoids.

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University is an NCI-Designated Comprehensive Cancer Center in Baltimore, MD. It was established in 1973 and received its NCI designation that same year as one of the first designated cancer centers in the country.

<span class="mw-page-title-main">Elizabeth Jaffee</span> American oncologist

Elizabeth M. Jaffee is an American oncologist specializing in pancreatic cancer and immunotherapy.

Nita Ahuja is a surgeon and the Chair of the Department of Surgery at Yale School of Medicine and Surgeon-in-Chief of Surgery at Yale New Haven Hospital. She is the first woman ever to serve as Chair of Surgery in Yale in its >200 year history. Before taking this position she was the first woman ever to be the Chief of Surgical Oncology at Johns Hopkins Hospital, Baltimore, USA. Ahuja researches in the field of epigenetics and is a passionate advocate of clinician scientist. She also served as the director of Sarcoma and peritoneal surface malignancy program. She is a surgeon-scientist and her research has been cited more than 11,000 times in scientific literature.

<span class="mw-page-title-main">Alan Yuille</span> English academic

Alan Yuille is a Bloomberg Distinguished Professor of Computational Cognitive Science with appointments in the departments of Cognitive Science and Computer Science at Johns Hopkins University. Yuille develops models of vision and cognition for computers, intended for creating artificial vision systems. He studied under Stephen Hawking at Cambridge University on a PhD in theoretical physics, which he completed in 1981.

Kathleen R. Cho is an American gynecological surgical pathologist. She is a Professor of Pathology and Internal Medicine at Michigan Medicine.

<span class="mw-page-title-main">John Neoptolemos</span> British surgeon

John P. Neoptolemos is a British surgeon and professor who specialised in pancreas research. His specific areas of research are diagnosis, biological predictors of treatment response and therapies of pancreatic cancer as well as acute, chronic, and hereditary pancreatitis. Neoptolemos was a British Department of Health Platinum Award holder from 2004. He was elected a Member of the Academia Europaea in 2019.

Akhilesh Pandey is an Indian-American proteomicist and a Professor at Department of Laboratory Medicine and Pathology, Center for Individualized Medicine of Mayo Clinic in Rochester, Minnesota, USA. He is also the founding director and chief scientific advisor of the Institute of Bioinformatics in Bangalore, India.

References

  1. https://www.ucls.uchicago.edu/alumni/alumni-awards
  2. 1 2 3 4 5 Hruban, Ralph H.; Zamboni, Giuseppe (March 2009). "Pancreatic Cancer". Archives of Pathology & Laboratory Medicine. 133 (3): 347–349. doi:10.5858/133.3.347. PMID   19260740.
  3. Michael Waldholz (24 March 1999). Curing Cancer: The Story of the Men and Women Unlocking the Secrets of Our Deadliest Illness. Simon and Schuster. pp. 18–. ISBN   978-0-684-84802-0.
  4. Daniel D. Von Hoff; Douglas Brian Evans; Ralph H. Hruban (2005). Pancreatic Cancer. Jones & Bartlett Learning. ISBN   978-0-7637-2178-7.
  5. Kim MS et al., 2014 (28 May 2014). "A draft map of the human proteome". Nature. 509 (7502). Nature Portfolio: 575–581. Bibcode:2014Natur.509..575K. doi:10.1038/nature13302. PMC   4403737 . PMID   24870542.{{cite journal}}: CS1 maint: numeric names: authors list (link)
  6. "Ralph Hruban, M.D., Professor of Pathology".
  7. "Expertscape: Pancreatic Neoplasms, November 2018". expertscape.com. November 2018. Retrieved 2018-11-26.
  8. "Home". halstedthedocumentary.org.