Range fractionation

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Graphical representation of range fractionation. In this diagram, 10 sensory neurons respond to fraction of the entire range of intensities of stimulus (blue, bottom). Together, all 10 of these neurons comprise the range of perceived stimuli", which is all of the discernable stimulus intensities to the system. Neuron response is indicated by "Sensory Neuron Activity" (or, Action Potential Firing Rate). The range of a single sensory neuron is indicated in yellow. In this depiction, low-intensity stimuli (light blue, left) would activate a single sensory neuron, whereas high-intensity stimuli (dark blue, right) may activate 3-4 neurons. The collective firing pattern of the sensory neurons will inform the nervous system about the stimulus properties. RangeFractionationforWikipedia2-03-03.png
Graphical representation of range fractionation. In this diagram, 10 sensory neurons respond to fraction of the entire range of intensities of stimulus (blue, bottom). Together, all 10 of these neurons comprise the range of perceived stimuli", which is all of the discernable stimulus intensities to the system. Neuron response is indicated by "Sensory Neuron Activity" (or, Action Potential Firing Rate). The range of a single sensory neuron is indicated in yellow. In this depiction, low-intensity stimuli (light blue, left) would activate a single sensory neuron, whereas high-intensity stimuli (dark blue, right) may activate 3-4 neurons. The collective firing pattern of the sensory neurons will inform the nervous system about the stimulus properties.

Range fractionation is a term used in biology to describe the way by which a group of sensory neurons are able to encode varying magnitudes of a stimulus. Sense organs are usually composed of many sensory receptors measuring the same property. These sensory receptors show a limited degree of precision due to an upper limit in firing rate. If the receptors are endowed with distinct transfer functions in such a way that the points of highest sensitivity are scattered along the axis of the quality being measured, the precision of the sense organ as a whole can be increased.

The basis of the idea of range fractionation is that each stimulus (for example, touch) has a range of intensities that can be sensed (light-touch to deep/hard-touch). For an organism to be able to sense a range of stimulus intensities, sensory neurons are tuned to fractions of the entire range. Collectively, the pattern of activity among the sensory neurons is how the organism can identify specific stimulus parameters. This was shown for proprioceptive neurons in the locust leg, [1] [2] proprioceptive neurons in the stick insect, [3] Johnston's Organ neurons in Drosophila, [4] and in auditory-sensing neurons in crickets. [5] [6] [7]

Range fraction is similar to the labeled line theory in that they both describe a phenomenon by which sensory neurons divide the task of encoding a range of stimulus intensities. However the difference lies within the downstream synaptic partners. Labeled line theory describes fully segregated channels postsynaptically. In contrast, sensory neurons that use range fractionation have common synaptic partners, and it is there collective activity that is informative of the stimulus type.

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<span class="mw-page-title-main">Stimulus (physiology)</span> Detectable change in the internal or external surroundings

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<span class="mw-page-title-main">Sensory neuron</span> Nerve cell that converts environmental stimuli into corresponding internal stimuli

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<span class="mw-page-title-main">Proprioception</span> Sense of self-movement, force, and body position

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A sense is a biological system used by an organism for sensation, the process of gathering information about the world through the detection of stimuli. Although in some cultures five human senses were traditionally identified as such, many more are now recognized. Senses used by non-human organisms are even greater in variety and number. During sensation, sense organs collect various stimuli for transduction, meaning transformation into a form that can be understood by the brain. Sensation and perception are fundamental to nearly every aspect of an organism's cognition, behavior and thought.

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<span class="mw-page-title-main">Subgenual organ</span>

The subgenual organ is an organ in insects that is involved in the perception of sound. The name refers to the location of the organ just below the knee in the tibia of all legs in most insects.

Hair-plates are a type of proprioceptor found in the folds of insect joints. They consist of a cluster of hairs, in which each hair is innervated by a single mechanosensory neuron. Functionally, hair-plates operate as "limit-detectors" by signaling the extreme ranges of motion of a joint.

<span class="mw-page-title-main">Femoral chordotonal organ</span> Sensory organ in insect legs

The femoral chordotonal organ is a group of mechanosensory neurons found in an insect leg that detects the movements and the position of the femur/tibia joint. It is thought to function as a proprioceptor that is critical for precise control of leg position by sending the information regarding the femur/tibia joint to the motor circuits in the ventral nerve cord and the brain

References

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