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Ready, Set, PrEP is a program of the U.S. Department of Health and Human Services (HHS) that provides free access to the HIV prevention medication PrEP for thousands of qualifying individuals. The program is a key component of Ending the HIV Epidemic: A Plan for America (EHE) initiative to expand access to PrEP and reduce new HIV diagnoses in the U.S.
During the State of the Union Address on February 5, 2019, the Donald Trump administration announced the operational plan EHE, which was developed by agencies across HHS to end the HIV epidemic and reduce the number of new HIV transmissions in the U.S. by 75% by 2025 and by 90% by 2030. [1]
According to Robert Goldstein, MD, over 1 million people at risk for HIV in the United States may benefit from pre-exposure prophylaxis (PrEP) medications, but fewer than one in four receive it. [2] To address the cost barriers to PrEP, HHS launched Ready, Set, PrEP in December 2019 with the goal of expanding access to those disproportionately impacted by HIV.
In August 2020, HHS contracted TrialCard as a distribution partner [9] to verify Ready, Set, PrEP participant eligibility, enrollments, maintain the network of participating pharmacies, and distribute the donated medications to uninsured participants. In early 2021, TrialCard will begin to offer mail-order delivery services for enrolled individuals.
The Ready, Set, PrEP program provides access to PrEP medications for free to people who qualify. To receive PrEP through the program, an individual must:
The costs of necessary clinic visits and lab test costs may vary depending on income and where the tests are given. It is recommended that those interested in the program speak with a healthcare provider to see if PrEP medication is the best option and to get a prescription.
HHS's Health Resources and Services Administration's Health Center program is working closely with healthcare professionals at more than 12,000 service sites and 1,400 health centers nationwide in order to provide HIV lab testing and access to PrEP medication. Anyone looking to find a clinic or provider that prescribes PrEP should use the locator tool or request a mail-order through participating pharmacies. [10]
A collective of over 24,000 pharmacies have partnered to donate their medication dispensing services to HHS in support of the Ready, Set, PrEP program and the EHE initiative. [11] Combined, these donating pharmacies represent almost half of the pharmacies in the U.S., the District of Columbia, Puerto Rico, and the U.S. Virgin Islands. The partnership allows for program enrollees to fill prescriptions for PrEP medication at one of the participating pharmacies or by mail order for free. [12] [13]
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Released during World AIDS Day 2020, the "I'm Ready" campaign is the latest addition to the Ready, Set, PrEP program. [14] The campaign features the stories of people from a variety of backgrounds sharing their experience with PrEP, aiming to highlight the challenges facing communities disproportionately impacted by HIV. In addition to HIV prevention, the campaign covers HIV testing, viral suppression, and HIV stigma.
The AIDS epidemic, caused by HIV, found its way to the United States between the 1970s and 1980s, but was first noticed after doctors discovered clusters of Kaposi's sarcoma and pneumocystis pneumonia in homosexual men in Los Angeles, New York City, and San Francisco in 1981. Treatment of HIV/AIDS is primarily via the use of multiple antiretroviral drugs, and education programs to help people avoid infection.
The United States President's Emergency Plan For AIDS Relief (PEPFAR) is a United States governmental initiative to address the global HIV/AIDS epidemic and help save the lives of those suffering from the disease. Launched by U.S. President George W. Bush in 2003, as of May 2020, PEPFAR has provided about $90 billion in cumulative funding for HIV/AIDS treatment, prevention, and research since its inception, making it the largest global health program focused on a single disease in history until the COVID-19 pandemic. PEPFAR is implemented by a combination of U.S. government agencies in over 50 countries and overseen by the Global AIDS Coordinator at the United States Department of State. As of 2023, PEPFAR has saved over 25 million lives, primarily in Sub-Saharan Africa.
Emtricitabine/tenofovir, sold under the brand name Truvada among others, is a fixed-dose combination antiretroviral medication used to treat and prevent HIV/AIDS. It contains the antiretroviral medications emtricitabine and tenofovir disoproxil. For treatment, it must be used in combination with other antiretroviral medications. For prevention before exposure, in those who are at high risk, it is recommended along with safer sex practices. It does not cure HIV/AIDS. Emtricitabine/tenofovir is taken by mouth.
Pre-exposure prophylaxis (PrEP) is the use of medications to prevent the spread of disease in people who have not yet been exposed to a disease-causing agent, usually a virus. The term typically refers to the use of antiviral drugs as a strategy for the prevention of HIV/AIDS. PrEP is one of a number of HIV prevention strategies for people who are HIV negative but who have a higher risk of acquiring HIV, including sexually active adults at increased risk of contracting HIV, people who engage in intravenous drug use, and serodiscordant sexually active couples.
AIDS service organizations are community-based organizations that provide support for people affected by HIV/AIDS. This article focuses on HIV/AIDS service organizations in the United States only.
HIV/AIDS was first diagnosed in 1981. As of year-end 2018, 160,493 people have been diagnosed with HIV in the United Kingdom and an estimated 7,500 people are living undiagnosed with HIV. New diagnoses are highest in gay/bisexual men, with an estimated 51% of new diagnosis reporting male same-sex sexual activity as the probable route of infection. Between 2009 and 2018 there was a 32% reduction in new HIV diagnosis, attributed by Public Health England (PHE) to better surveillance and education. PHE has described an "outbreak" in Glasgow amongst people who inject drugs, and has campaigns targeting men who have sex with men in London and other major cities. London was the first city in the world to reach the World Health Organization target for HIV, set at 90% of those with HIV diagnosed, 90% of those diagnosed on HAART and 90% of those on HAART undetectable. The UK as a whole later achieved the same target. Under the Equality Act 2010, it is illegal to discriminate against someone based on their HIV status in the UK.
Health Mart is an independent pharmacy franchise with more than 5,000 member pharmacies across all 50 states. Each pharmacy is locally owned and operated, allowing Health Mart pharmacy owners to tailor their offerings to the specific communities they serve.
AIDS Foundation of Chicago is a locally based, non-profit organization that advocates for HIV/AIDS prevention as well as serves as a general resource for the HIV/AIDS community. Founded in 1985, some of their better-known accomplishments include hosting fundraisers to support the distribution of HIV/AIDS related medications in the city, funding the Open Door Health Center, and launching their “Getting to Zero” plan. Their cause seeks to increase the amount of resources available to the HIV/AIDS community as resources are too few and far between. Similar to other city organizations focused on sexual health such as Howard Brown Health, AFC makes getting access to treatment easier for all patients, decreases the stigma around treatment, and promotes the awareness and acceptance of those who live with HIV and/or AIDS.
The history of HIV/AIDS in Australia is distinctive, as Australian government bodies recognised and responded to the AIDS pandemic relatively swiftly, with the implementation of effective disease prevention and public health programs, such as needle and syringe programs (NSPs). As a result, despite significant numbers of at-risk group members contracting the virus in the early period following its discovery, Australia achieved and has maintained a low rate of HIV infection in comparison to the rest of the world.
HIV.gov, formerly known as AIDS.gov, is an internet portal for all United States federal domestic HIV and AIDS resources and information. On World AIDS Day, December 1, 2006, the U.S. Department of Health and Human Services launched AIDS.gov. The site contains content and links that guide users to their desired information.
APLA Health is a non-profit organization that is focused on building health equity and promoting wellbeing for the LGBT and people living with HIV.
HIV and AIDS is a major public health issue in Zimbabwe. The country is reported to hold one of the largest recorded numbers of cases in Sub-Saharan Africa. According to reports, the virus has been present in the country since roughly 40 years ago. However, evidence suggests that the spread of the virus may have occurred earlier. In recent years, the government has agreed to take action and implement treatment target strategies in order to address the prevalence of cases in the epidemic. Notable progress has been made as increasingly more individuals are being made aware of their HIV/AIDS status, receiving treatment, and reporting high rates of viral suppression. As a result of this, country progress reports show that the epidemic is on the decline and is beginning to reach a plateau. International organizations and the national government have connected this impact to the result of increased condom usage in the population, a reduced number of sexual partners, as well as an increased knowledge and support system through successful implementation of treatment strategies by the government. Vulnerable populations disproportionately impacted by HIV/AIDS in Zimbabwe include women and children, sex workers, and the LGBTQ+ population.
Electronic prescription is the computer-based electronic generation, transmission, and filling of a medical prescription, taking the place of paper and faxed prescriptions. E-prescribing allows a physician, physician assistant, pharmacist, or nurse practitioner to use digital prescription software to electronically transmit a new prescription or renewal authorization to a community or mail-order pharmacy. It outlines the ability to send error-free, accurate, and understandable prescriptions electronically from the healthcare provider to the pharmacy. E-prescribing is meant to reduce the risks associated with traditional prescription script writing. It is also one of the major reasons for the push for electronic medical records. By sharing medical prescription information, e-prescribing seeks to connect the patient's team of healthcare providers to facilitate knowledgeable decision making.
HIV/AIDS was first detected in Canada in 1982. In 2018, there were approximately 62,050 people living with HIV/AIDS in Canada. It was estimated that 8,300 people were living with undiagnosed HIV in 2018. Mortality has decreased due to medical advances against HIV/AIDS, especially highly active antiretroviral therapy (HAART).
Discrimination against people with HIV/AIDS or serophobia is the prejudice, fear, rejection, and stigmatization of people with HIV/AIDS. Marginalized, at-risk groups such as members of the LGBTQ+ community, intravenous drug users, and sex workers are most vulnerable to facing HIV/AIDS discrimination. The consequences of societal stigma against PLHIV are quite severe, as HIV/AIDS discrimination actively hinders access to HIV/AIDS screening and care around the world. Moreover, these negative stigmas become used against members of the LGBTQ+ community in the form of stereotypes held by physicians.
The 340B Drug Pricing Program is a US federal government program created in 1992 that requires drug manufacturers to provide outpatient drugs to eligible health care organizations and covered entities at significantly reduced prices. The intent of the program is to allow covered entities to "stretch scarce federal resources as far as possible, reaching more eligible patients and providing more comprehensive services." Maintaining services and lowering medication costs for patients is consistent with the purpose of the program, which is named for the section authorizing it in the Public Health Service Act (PHSA) It was enacted by Congress as part of a larger bill signed into law by President George H. W. Bush.
HIV in pregnancy is the presence of an HIV/AIDS infection in a woman while she is pregnant. There is a risk of HIV transmission from mother to child in three primary situations: pregnancy, childbirth, and while breastfeeding. This topic is important because the risk of viral transmission can be significantly reduced with appropriate medical intervention, and without treatment HIV/AIDS can cause significant illness and death in both the mother and child. This is exemplified by data from The Centers for Disease Control (CDC): In the United States and Puerto Rico between the years of 2014–2017, where prenatal care is generally accessible, there were 10,257 infants in the United States and Puerto Rico who were exposed to a maternal HIV infection in utero who did not become infected and 244 exposed infants who did become infected.
Transgender sex workers are transgender people who work in the sex industry or perform sexual services in exchange for money or other forms of payment. In general, sex workers appear to be at great risk for serious health problems related to their profession, such as physical and sexual assault, robbery, murder, physical and mental health problems, and drug and alcohol addiction. Though all sex workers are at risk for the problems listed, some studies suggest that sex workers who engage in street-based work have a higher risk for experiencing these issues. Transgender sex workers experience high degrees of discrimination both in and outside of the sex industry and face higher rates of contracting HIV and experiencing violence as a result of their work. In addition, a clear distinction needs to be made between consensual sex work and sex trafficking where there is a lack of control and personal autonomy.
In January 2018, the provincial government of British Columbia (BC) began providing individuals at high risk of HIV infection with pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP) at no cost. High risk individuals include men and trans women who have sex with men, people who inject drugs, and people who have sex with people living with HIV. One year following this policy change, which is delivered as part of the British Columbia Centre for Excellence in HIV/AIDS (BC-CfE)'s Drug Treatment Program, almost 3,300 people have been prescribed with PrEP or PEP.
HIV/AIDS in Hong Kong was first reported in 1984. As of the end of 2021, 11,232 people have been diagnosed with HIV in Hong Kong. New diagnoses are highest in gay and bisexual men, with 53.5% of new diagnoses occurring in men who have sex with men. The rate of reported transmissions peaked in 2015, and has since decreased by 49.1%.
This article incorporates public domain material from websites or documents of the United States Department of Health and Human Services.