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Prostate cancer is the uncontrolled growth of cells in the prostate, a gland in the male reproductive system below the bladder. Early prostate cancer usually causes no symptoms. As the tumor grows, it can damage nearby organs causing erectile dysfunction, blood in the urine or semen, and trouble urinating. Some tumors eventually spread to other areas of the body, particularly the bones and lymph nodes. There, tumors cause severe bone pain, leg weakness or paralysis, and eventually death.
Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), P-30 antigen, is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland.
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Samuel Ray Denmeade is a Professor of Oncology, Urology and Pharmacology and Molecular Sciences at the Johns Hopkins University School of Medicine. Over 10 of his published papers have each been cited over 100 times.
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Prostate cancer screening is the screening process used to detect undiagnosed prostate cancer in men without signs or symptoms. When abnormal prostate tissue or cancer is found early, it may be easier to treat and cure, but it is unclear if early detection reduces mortality rates.
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Andrew Julian Vickers is a biostatistician and attending research methodologist at Memorial Sloan Kettering Cancer Center. Since 2013, he has also been professor of public health at Weill Cornell Medical College. He is the statistical editor for the peer-reviewed journal European Urology.
Kevin M. Slawin is an American physician and the founder of Bellicum Pharmaceuticals and the Vanguard Urologic Institute at Memorial Hermann Medical Group. He was also the Director of Urology at Memorial Hermann Hospital. Slawin specializes in the diagnosis and treatment of urologic cancers and robotic surgery. He is also possesses patents related to the advancement of prostate cancer diagnosis, staging and treatment and to the cellular immunotherapy of cancer.
Ronald S. Weinstein was an American pathologist. He was a professor at the University of Arizona College of Medicine-Tucson. Weinstein served for 32 years as an academic pathology department chair, in Chicago, Illinois and then Tucson, Arizona, while also serving as a serial entrepreneur engaged in university technology transfer.
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References
- ↑ Should Men Get PSA Tests to Screen for Prostate Cancer?, Wall Street Journal, Feb 14, 2013
- ↑ University of Arizona College of Medicine – Tucson Department of Pathology profile. "Archived copy". Archived from the original on 2021-01-22. Retrieved 2019-09-04.
{{cite web}}: CS1 maint: archived copy as title (link) CS1 maint: bot: original URL status unknown (link). - ↑ Prostate cancer test has been misused for money, New Scientist, Feb 12, 2014
- ↑ Kotulak, Ronald. "A healthy sex life is, well, good and healthy", Chicago Tribune , Chicago, Illinois, 135th year, number 256, September 13, 1981, section 1, page 18. (subscription required)
- ↑ "Arizona Cancer Center staffer publishes 4th Book", Tucson Citizen , Tucson, Arizona, volume 137, number 250, October 18, 2007, Calendar section, page 25. (subscription required)
