Kurt Wüthrich is a Swiss chemist/biophysicist and Nobel Chemistry laureate, known for developing nuclear magnetic resonance (NMR) methods for studying biological macromolecules.
Edward Mills Purcell was an American physicist who shared the 1952 Nobel Prize for Physics for his independent discovery of nuclear magnetic resonance in liquids and in solids. Nuclear magnetic resonance (NMR) has become widely used to study the molecular structure of pure materials and the composition of mixtures. Friends and colleagues knew him as Ed Purcell.
Solid-state NMR (ssNMR) spectroscopy is a technique for characterizing atomic level structure in solid materials e.g. powders, single crystals and amorphous samples and tissues using nuclear magnetic resonance (NMR) spectroscopy. The anisotropic part of many spin interactions are present in solid-state NMR, unlike in solution-state NMR where rapid tumbling motion averages out many of the spin interactions. As a result, solid-state NMR spectra are characterised by larger linewidths than in solution state NMR, which can be utilized to give quantitative information on the molecular structure, conformation and dynamics of the material. Solid-state NMR is often combined with magic angle spinning to remove anisotropic interactions and improve the resolution as well as the sensitivity of the technique.
The National High Magnetic Field Laboratory (MagLab) is a facility at Florida State University, the University of Florida, and Los Alamos National Laboratory in New Mexico, that performs magnetic field research in physics, biology, bioengineering, chemistry, geochemistry, biochemistry. It is the only such facility in the US, and is among twelve high magnetic facilities worldwide. The lab is supported by the National Science Foundation and the state of Florida, and works in collaboration with private industry.
John Stewart Waugh was an American chemist and Institute Professor at the Massachusetts Institute of Technology. He is known for developing average hamiltonian theory and using it to extend NMR spectroscopy, previously limited to liquids, to the solid state. He is the author of ANTIOPE, a freeware general purpose Windows-based simulator of the spectra and dynamics of nuclear magnetic resonance (NMR). He has also used systems of a few coupled spins to illustrate the general requirements for equilibrium and ergodicity in isolated systems.
Rafael Brüschweiler is a scientist who studies nuclear magnetic resonance (NMR). He is credited for the development of Covariance NMR, which shortens the NMR measurement time for multidimensional spectra of both solution and solid-state NMR. It also allows for easier analysis and interpretation. For this achievement he was awarded the Laukien Prize in NMR Spectroscopy at the 47th Experimental Nuclear Magnetic Resonance Conference (ENC). He is also a leading scientist in NMR-based metabolomics and protein NMR.
Joachim Heinrich Seelig is a German physical chemist and specialist in NMR Spectroscopy. He is one of the founding fathers of the Biozentrum of the University of Basel.
Professor Ramakrishna Vijayacharya Hosur is an Indian biophysical scientist, known for his expertise in the areas of nuclear magnetic resonance and molecular biophysics. The Government of India honoured him, in 2014, by awarding him the Padma Shri, the fourth highest civilian award, for his contributions to the fields of science and technology.
G. Marius Clore MAE, FRSC, FRS is a British-born, Anglo-American molecular biophysicist and structural biologist. He was born in London, U.K. and is a dual US/U.K. Citizen. He is a Member of the National Academy of Sciences, a Fellow of the Royal Society, a NIH Distinguished Investigator, and the Chief of the Molecular and Structural Biophysics Section in the Laboratory of Chemical Physics of the National Institute of Diabetes and Digestive and Kidney Diseases at the U.S. National Institutes of Health. He is known for his foundational work in three-dimensional protein and nucleic acid structure determination by biomolecular NMR spectroscopy, for advancing experimental approaches to the study of large macromolecules and their complexes by NMR, and for developing NMR-based methods to study rare conformational states in protein-nucleic acid and protein-protein recognition. Clore's discovery of previously undetectable, functionally significant, rare transient states of macromolecules has yielded fundamental new insights into the mechanisms of important biological processes, and in particular the significance of weak interactions and the mechanisms whereby the opposing constraints of speed and specificity are optimized. Further, Clore's work opens up a new era of pharmacology and drug design as it is now possible to target structures and conformations that have been heretofore unseen.
Dennis Torchia is an American biophysicist who specialized in NMR spectroscopy. He spent most of his career at the National Institute of Dental and Craniofacial Research (NIDCR), part of the United States National Institutes of Health, where he served as Chief of the Structural Biology Unit before his retirement in 2006.
David Lyndon Emsley FRSC is a British chemist specialising in solid-state nuclear magnetic resonance and a Professor at EPFL. He was awarded the 2012 Grand Prix Charles-Leopold Mayer of the French Académie des Sciences and the 2015 Bourke Award of the Royal Society of Chemistry.
Geoffrey Bodenhausen is a French chemist specializing in nuclear magnetic resonance, being highly cited in his field. He is a Corresponding member of the Royal Netherlands Academy of Arts and Sciences and a Fellow of the American Physical Society. He is professeur émérite at the Department of Chemistry at the École Normale Supérieure (ENS) in Paris and professeur honoraire at the Laboratory of Biomolecular Magnetic Resonance of the École Polytechnique Fédérale de Lausanne (EPFL). He is a member of the editorial board of the journal Progress in Nuclear Magnetic Resonance Spectroscopy. He is the chair of the editorial board of the journal Magnetic Resonance.
Marc Baldus is a physicist and professor of NMR spectroscopy at Utrecht University. He is especially known for his work in the field of structural biology using solid-state nuclear magnetic resonance (ssNMR) spectroscopy. He applies ssNMR methods to establish structure-function relationships in complex biomolecular systems including membrane and Amyloid proteins. In addition, he develops cellular NMR methods to study large molecular transport and insertion systems in bacteria as well as signal transduction mechanisms in eukaryotic cells.
Benjamin Lax was a solid-state and plasma physicist.
Hartmut Oschkinat is a German structural biologist and professor for chemistry at the Free University of Berlin. His research focuses on the study of biological systems with solid-state nuclear magnetic resonance.
Gerhard Wagner is a German-American physicist currently the Elkan Rogers Blout Professor of Biological Chemistry and Molecular Pharmacology at Harvard Medical School and is an Elected Fellow of the American Association for the Advancement of Science, German National Academy of Sciences Leopoldina, American Academy of Arts and Sciences, National Academy of Sciences and International Society of Magnetic Resonance. He is considered one of the pioneers in Biological Nuclear Magnetic Resonance (NMR) spectroscopy (Bio-NMR) and his research has been focused on protein structure, dynamics and stability, and on the relation of these to protein function. He is a structural biologist and is recognized for his work on the development of NMR spectroscopy for determination of protein structures in solution and characterizing protein dynamics.
Lucio Frydman is an Israeli chemist whose research focuses on magnetic resonance imaging (MRI), nuclear magnetic resonance (NMR) and solid-state NMR. He was awarded the 2000 Günther Laukien Prize, the 2013 Russell Varian Prize and the 2021 Ernst Prize. He is Professor and Head of the Department of Chemical and Biological Physics at the Weizmann Institute of Science in Israel and Chief Scientist in Chemistry and Biology at the US National High Magnetic Field Laboratory in Tallahassee, Florida. He is a fellow of the International Society of Magnetic Resonance and of the International Society of Magnetic Resonance in Medicine. He was the Editor-in-Chief of the Journal of Magnetic Resonance (2011-2021).
Malcolm Harris Levitt is a British-born physical chemist and nuclear magnetic resonance (NMR) spectroscopist. He is Professor in Physical Chemistry at the University of Southampton and was elected a Fellow of the Royal Society in 2007.
Alexander Benjamin Barnes is an American chemist. Educated at Whitman College and the Massachusetts Institute of Technology, he has taught at Washington University in St. Louis and ETH Zurich.
Mei Hong is a Chinese-American biophysical chemist and Professor of Chemistry at the Massachusetts Institute of Technology. She is known for her creative development and application of solid-state nuclear magnetic resonance (ssNMR) spectroscopy to elucidate the structures and mechanisms of membrane proteins, plant cell walls, and amyloid proteins. She has received a number of recognitions for her work, including the American Chemical Society Nakanishi Prize in 2021, Günther Laukien Prize in 2014, the Protein Society Young Investigator award in 2012, and the American Chemical Society’s Pure Chemistry award in 2003.
