Robert J. Linhardt | |
---|---|
Alma mater | MIT Johns Hopkins University Marquette University |
Awards | Scientific American 10 American Chemical Society Melville L. Wolfrom Award American Chemical Society Claude S. Hudson Award American Chemical Society Horace S. Isbell AAAS Fellow |
Scientific career | |
Fields | Bioengineering Metabolic Engineering Biomolecular Interaction The Interactome Carbohydrate Analysis Structural Biology Glycobiology Glycomics Synthetic Carbohydrate Chemistry Nanobiotechnology Nano/Micron-scale Devices |
Institutions | Rensselaer Polytechnic Institute |
Academic advisors | Robert S. Langer Brown L. Murr |
Robert J. Linhardt is the Ann and John Broadbent, Jr. '59 Senior Constellation Professor Biocatalysis & Metabolic Engineering at Rensselaer Polytechnic Institute.
His primary appointment at RPI is based in the Center for Biotechnology and Interdisciplinary Studies, consisting of joint appointments with the Department of Chemistry & Chemical Biology, Department of Biology, Department of Chemical and Biological Engineering, Department of Biomedical Engineering and the Rensselaer Nanotechnology Center. He is highly cited in his field, with over 100 papers having each over 100 citations. [1]
Prior to joining RPI in 2003, he was then a professor for 21 years at the University of Iowa. During his career in Iowa, he spent eight years as the F. Wendell Miller Distinguished Professor of Chemistry and ten years as a member of the executive committee of the Center for Biocatalysis & Bioprocessing. [2] Since 2008 Linhardt's group has been working on a collaboration to bioengineer Heparin from E. coli. This is in part a response to the outbreak of adverse heparin reactions in 2007. [3] This work helped earn him a spot in the Scientific American 10, for the 10 people who “demonstrated outstanding commitment to assuring that the benefits of new technologies and knowledge will accrue to humanity.” [4] [5] He was the 2010 recipient of the Melville L. Wolfrom Award of the American Chemical Society. [6]
Rensselaer Polytechnic Institute is a private research university in Troy, New York, with an additional campus in Hartford, Connecticut. A third campus in Groton, Connecticut, closed in 2018. RPI was established in 1824 by Stephen Van Rensselaer and Amos Eaton for the "application of science to the common purposes of life" and is the oldest technological university in the English-speaking world and the Western Hemisphere.
Amos Eaton was an American botanist, geologist, and educator who is considered the founder of the modern scientific prospectus in education, which was a radical departure from the American liberal arts tradition of classics, theology, lecture, and recitation. Eaton co-founded the Rensselaer School in 1824 with Stephen van Rensselaer III "in the application of science to the common purposes of life". His books in the eighteenth century were among the first published for which a systematic treatment of the United States was attempted, and in a language that all could read. His teaching laboratory for botany in the 1820s was the first of its kind in the country. Eaton's popular lectures and writings inspired numerous thinkers, in particular women, whom he encouraged to attend his public talks on experimental philosophy. Emma Willard would found the Troy Female Seminary, and Mary Mason Lyon, the Mount Holyoke Female Seminary. Eaton held the rank of senior professor at Rensselaer until his death in 1842.
Biocatalysis refers to the use of living (biological) systems or their parts to speed up (catalyze) chemical reactions. In biocatalytic processes, natural catalysts, such as enzymes, perform chemical transformations on organic compounds. Both enzymes that have been more or less isolated and enzymes still residing inside living cells are employed for this task. Modern biotechnology, specifically directed evolution, has made the production of modified or non-natural enzymes possible. This has enabled the development of enzymes that can catalyze novel small molecule transformations that may be difficult or impossible using classical synthetic organic chemistry. Utilizing natural or modified enzymes to perform organic synthesis is termed chemoenzymatic synthesis; the reactions performed by the enzyme are classified as chemoenzymatic reactions.
Jonathan S. Dordick is an institute professor of chemical and biological engineering at Rensselaer Polytechnic Institute and holds joint appointments in the departments of biomedical engineering and biological sciences. In 2008 he became director of the Center for Biotechnology and Interdisciplinary Studies. In 2012 Dordick became the vice president for research at RPI. He became Special Advisor to the RPI President for Strategic Initiatives in 2018,
The Winslow Chemical Laboratory was a laboratory of the Rensselaer Polytechnic Institute campus in Troy, New York, United States, which finished construction in 1866. It is named in honor of the 5th President of RPI, John F. Winslow, who donated half of the construction cost. The building is brick with stone trimmings and was originally constructed with butternut, chestnut and black walnut. The whole building was fitted for complete courses in general and analytical chemistry. The design and construction was overseen by Professor Henry B. Nason, head of the department of chemistry at the Institute. The lower story contained the metallurgical laboratory and second story contained the chemical laboratory, store rooms and work rooms. The laboratory could accommodate about 40 students. The third story contained a lecture room, a private study, the library and a recitation room. The library of chemical books was established by a donation of several sets of journals and a gift of three hundred dollars from John F. Winslow.
Robert Gustav Loewy is an aerospace engineer who has been influential in the development of rotary-wing vertical take-off and landing aircraft. He was born in Philadelphia, Pennsylvania.
The history of Rensselaer Polytechnic Institute (RPI) spans nearly two hundred years beginning with its founding in 1824. RPI is the oldest continuously operating technological university in both the English-speaking world and the Americas. The Institute was the first to grant a civil engineering degree in the United States, in 1835. More recently, RPI also offered the first environmental engineering degree in the United States in 1961, and possibly the first ever undergraduate degree in video game design, in 2007.
Henry Bradford Nason was a United States chemist.
Benjamin Guy Davis is Professor of Chemical biology in the Department of Pharmacology and a member of the Faculty in the Department of Chemistry at the University of Oxford and a Fellow of Pembroke College, Oxford. He holds the role of Science Director for Next Generation Chemistry (2019-2024) at the Rosalind Franklin Institute.
Nigel Shaun Scrutton is a British biochemist and biotechnology innovator known for his work on enzyme catalysis, biophysics and synthetic biology. He is Director of the UK Future Biomanufacturing Research Hub, Director of the Fine and Speciality Chemicals Synthetic Biology Research Centre (SYNBIOCHEM), and Co-founder, Director and Chief Scientific Officer of the 'fuels-from-biology' company C3 Biotechnologies Ltd. He is Professor of Enzymology and Biophysical Chemistry in the Department of Chemistry at the University of Manchester. He is former Director of the Manchester Institute of Biotechnology (MIB).
James "Jim" P. Ferris was an American chemist. He is known for his contributions to the understanding of the origins of life on Earth, specifically by demonstrating a successful mechanism of clay-catalyzed polymerization of RNA, providing further evidence for the RNA World Hypothesis. Additionally, his work in atmospheric photochemistry has illuminated many of the chemical processes which occur in the atmospheres of Jupiter and Saturn's moon, Titan.
Julie Ezold is a nuclear engineer at the Oak Ridge National Laboratory. She is campaign manager for the 252-Californium Campaign and was involved with the discovery of Tennessine.
Vincent Meunier is a Belgian/American condensed matter and materials physicist known for his theoretical and computational research on electronic, optoelectronic, and structural properties of low-dimensional materials. He is the Department Head and P. B. Breneman Chair and Professor in the Department of Engineering Science and Mechanics at Pennsylvania State University. Among his contributions are the quantum mechanical description of processes responsible for scanning tunneling image formation in low-dimensional materials, the development of a microscopic theory of nanocapacitors, and contributions to the theory of electronic transport and ultra-low frequency vibrational modes in van der Waals heterostructures. He is a Fellow of the American Physical Society (APS), of the Institute of Physics (IOP), and of the American Association for the Advancement of Science (AAAS). He is the founding Editor-in-Chief of the Open Access Elsevier journal Carbon Trends.
Pierre Sinaÿ, born on April 11, 1938, in Aulnay-sous-Bois (Seine-et-Oise), is a French organic chemist.
Ricketts Building is a building that is home to the Department of Chemical and Biological Engineering at the Rensselaer Polytechnic Institute in Troy, New York. It is named for Palmer C. Ricketts, the ninth president of Rensselaer Polytechnic Institute. The building opened in 1935. It is currently used for labs, lectures, and some clubs.
Nicholas John Turner, is a British chemist and a Professor in the Department of Chemistry at The University of Manchester. His research in general is based on biochemistry and organic chemistry, specifically on biotechnology, cell biology, biocatalysis and organic synthesis.
Gaetano T. Montelione is an American biophysical chemist, Professor of Chemistry and Chemical Biology, and Constellation Endowed Chair in Structural Bioinformatics at Rensselaer Polytechnic Institute in Troy, NY.
David W. Wood is an American chemical engineer who is Professor of Chemical and Biomolecular Engineering at Ohio State University. Wood is also associated with the Department of Chemistry and Biochemistry and Molecular Biophysics Training Program.