Rs28363170

SNP: rs28363170
Gene	SLC6A3
Chromosome	5
External databases
Ensembl	Human SNPView
dbSNP	28363170
HapMap	28363170
SNPedia	28363170

In genetics, rs28363170 (DAT1-VNTR) is a genetic variation at SLC6A3 , the gene that encodes the dopamine transporter. It is polymorphism as a 40 base pairs VNTR in the 3' untranslated region. It is a deletion/insertion polymorphism (DIP). ^[1]

The 9-repeat and the 10-repeat are the most common alleles. ^[2]

References

1. "Rs28363170 RefSNP Report - DBSNP - NCBI".
2. David Mrazek (2010). Psychiatric Pharmacogenomics. Oxford University Press.

Further

• A. Sano; K. Kondoh; Y. Kakimoto (May 1993). "A 40-nucleotide repeat polymorphism in the human dopamine transporter gene". Human Genetics . 91 (4): 405–406. doi:10.1007/BF00217369. PMID   8500798. S2CID   39416578.
• Joober, R.; Grizenko, N; Sengupta, S; Amor, LB; Schmitz, N; Schwartz, G; Karama, S; Lageix, P; et al. (2007). "Dopamine transporter 3'-UTR VNTR genotype and ADHD: a pharmaco-behavioural genetic study with methylphenidate". Neuropsychopharmacology. 32 (6): 1370–1376. doi:10.1038/sj.npp.1301240. PMID   17063150. S2CID   2944059.