Shahinaz Gadalla | |
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Alma mater | Ain Shams University Faculty of Medicine University of Maryland, Baltimore |
Scientific career | |
Fields | Epidemiology, cancer biomarkers, hematopoietic stem cell transplantation |
Institutions | National Cancer Institute |
Shahinaz Mohamed Aly Gadalla is a physician-scientist and cancer epidemiologist who researches cancer biomarkers and hematopoietic stem cell transplantation. She is a senior investigator in the clinical genetics branch at the National Cancer Institute.
Shahinaz Mohamed Aly Gadalla was born to Mohamed and Sabah. [1] She earned a M.B.Bch from Ain Shams University Faculty of Medicine In 1996. [1] [2] She completed a medical internship in 1998 at Ain Shams University Hospitals. [1] Gadallah completed a M.S. (2005) in epidemiology and preventative medicine and a Ph.D. (2008) in epidemiology from the University of Maryland, Baltimore. [1] [2] Her dissertation was titled, Systemic autoimmune rheumatic diseases and breast cancer risk in elderly women. [1] Sania Amr was her doctoral advisor. [1] Gadalla dedicated her dissertation to her daughter. [1] She joined the clinical genetics branch (CGB) within the National Cancer Institute (NCI) division of cancer epidemiology and genetics as a cancer prevention fellow in 2008. [2]
Gadalla was promoted to a staff scientist in 2011 and was appointed as an Earl Stadtman Tenure-Track Investigator in 2014. [2] She was awarded National Institutes of Health (NIH) scientific tenure and appointed senior investigator in 2022. [2] Gadalla's research interests focus on identifying and characterizing individuals at high risk of developing cancer and discovering predictive and prognostic biomarkers that may guide therapeutic decisions for those patients. [2] In 2011, Gadalla and colleagues were the first to report epidemiological evidence of excess cancer risk in myotonic dystrophy (DM) patients. [2] She also researches molecular predictors of outcomes after hematopoietic cell transplantation. [2] Gadalla's work focuses on severe aplastic anemia and myeloid neoplasms with a goal of identifying biomarkers that can guide donor selection or patient risk stratification. [2] Her investigations include markers of cellular aging, germline genetic variants, and somatic copy-number alterations. [2]
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