Sharon K. Inouye | |
---|---|
Born | Culver City, California, USA |
Spouse | Stephen Lewis Helfand (m. 1983) |
Academic background | |
Education | BA, English literature, 1977, Pomona College MD, 1981, UCSF Medical Center MPH, 1989, Yale University |
Academic work | |
Institutions | Harvard Medical School Yale University |
Sharon Kiyomi Inouye is an American geriatrician. She is the Director of the Aging Brain Center at the Hinda and Arthur Marcus Institute for Aging Research,as well as a professor of medicine at the Harvard Medical School and Beth Israel Deaconess Medical Center. Her career has focused on maintaining healthy brain aging,preventing delirium and functional decline,and optimizing healthcare for older adults. Her recent work has focused on healthy longevity and combating ageism. [1]
Inouye was born to parents Lily Ann and Mitsuo Inouye in Culver City,California,the second of four children. [2] She attended Pomona College for her undergraduate degree where she majored in English literature before studying medicine at the UCSF Medical Center,matriculating there as the youngest of her class. [3] She completed her internal medicine residency as UCSF and Beth Israel Deaconess Medical Center (Harvard). As a senior resident in internal medicine at Moffitt Hospital in 1983,she married neurobiologist Stephen Lewis Helfand. [2]
Upon completing her medical degree,Inouye completed a post-doctoral research fellowship in general medicine at Stanford with Dr. Harold Sox prior to completing the Robert Wood Johnson Clinical Scholars Program at Yale with Drs. Alvan Feinstein and Ralph Horwitz,where she completed an MPH degree in 1989. [4] She joined the faculty at Yale University from 1985 to 2005. [5] As a professor at Yale,she focused on translating clinical investigation from its theoretical basis to practical applications that will improve clinical care and quality of life for older persons. [6] In the 1990s,she focused her research on preventing delirium amongst the elderly in hospitals. As such,she developed the Confusion Assessment Method as a new tool for the identification of delirium in 1990,now the most widely used tool for identification of delirium worldwide. [7] In 1999,she published a landmark study in the New England Journal of Medicine demonstrating a 40% reduction in delirium using a multi-component non-pharmacologic program targeted at delirium risk factors. [8] These strategies,which included orientation,early mobilization,providing nutrition and hydration,and enhancing sleep without medication using warm milk and backrubs,were encapsulated in the Hospital Elder Life Program (HELP). [9] Yale-New Haven Hospital adopted her prevention methods such as warm milk and backrubs as a routine method. [10] She also developed the Hospitals Elder Life Program (HELP) to prevent delirium in hospitalized patients. [11] By 2002,Inouye was serving as Director of the Aging Brain Center at the Hinda and Arthur Marcus Institute for Aging Research and was the Milton and Shirley F. Levy Family Chair at Yale. As a result of her research,she was elected a member of the American Society for Clinical Investigation. [12] Inouye was then awarded the 2003 Ewald W. Busse Research Award in Biomedical Sciences, [6] the 2005 Leonard Tow Humanism in Medicine Award (Arnold P. Gold Foundation), [13] and elected to the Society of Distinguished Teachers,Yale University School of Medicine,in 2005. [1] Inouye was a tenured full professor at Yale,director of the Yale Mentored Clinical Research Scholars Program,co-director of the Yale Program on Aging,and Claude D. Pepper Older Americans Independence Center,director of the Yale Mentorship Program in Patient-Oriented Research on Aging,and director of Patient-Oriented Research for the Yale Investigative Medicine Program. [1] She was also appointed co-director of the Yale Program on Aging and Yale's Claude D. Pepper Older Americans Independence Center. [14]
Inouye left Yale University in 2005 to join the Beth Israel Deaconess Medical Center,Harvard Medical School,and Hebrew SeniorLife. In 2012,she was elected a member of the National Academy of Medicine. [15] A few years later,Inouye was recognized by Thomson Reuters ScienceWatch as being amongst the world's most influential scientific minds for 2014. [16] In October 2016,Inouye received a federal grant to help establish an interdisciplinary Network for Investigation of Delirium across the United States. [17] Later that year,she also earned the M. Powell Lawton Award for her significant contributions in gerontology. [18] In 2017,Inouye was named a 2017 Health and Aging Policy Fellow and an American Political Science Association Congressional Fellow. [19]
During the COVID-19 pandemic,Inouye was selected as the Next Avenue 2020 Influencer in Aging,in part because of her work advocating for older adults during the COVID-19 pandemic. [20]
She was named editor-in-chief of JAMA Internal Medicine effective July 1,2023. [21]
Delirium is a specific state of acute confusion attributable to the direct physiological consequence of a medical condition,effects of a psychoactive substance,or multiple causes,which usually develops over the course of hours to days. As a syndrome,delirium presents with disturbances in attention,awareness,and higher-order cognition. People with delirium may experience other neuropsychiatric disturbances,including changes in psychomotor activity,disrupted sleep-wake cycle,emotional disturbances,disturbances of consciousness,or,altered state of consciousness,as well as perceptual disturbances,although these features are not required for diagnosis.
The Baylor College of Medicine (BCM) is a private medical school in Houston,Texas,United States. Originally as the Baylor University College of Medicine from 1903 to 1969,the college became independent with the current name and has been separate from Baylor University since 1969. The college consists of four schools:the School of Medicine,the Graduate School of Biomedical Sciences,the School of Health Professions,and the National School of Tropical Medicine.
Alvaro Pascual-Leone is a Spanish-American Professor of neurology at Harvard Medical School,with which he has been affiliated since 1997. He is currently a Senior Scientist at the Hinda and Arthur Marcus Institute for Aging Research at Hebrew SeniorLife. He was previously the Director of the Berenson-Allen Center for Noninvasive Brain Stimulation and Program Director of the Harvard-Thorndike Clinical Research Center of the Beth Israel Deaconess Medical Center in Boston.
Southern Illinois University School of Medicine is a medical school located in Springfield,the capital of the U.S. state of Illinois. It is part of the Southern Illinois University system,which includes a campus in Edwardsville as well as the flagship in Carbondale. The medical school was founded in 1970 and achieved full accreditation in 1972. It was founded to relieve a chronic shortage of physicians in downstate Illinois.
The State University of New York Upstate Medical University is a public medical school in Syracuse,New York. Founded in 1834,Upstate is the 15th oldest medical school in the United States and is the only medical school in Central New York. The university is part of the State University of New York (SUNY) system.
Yale Cancer Center (YCC) was founded in 1974 as a result of an act of Congress in 1971,which declared the nation's "war on cancer". It is one of a network of 56 Comprehensive Cancer Centers designated by the National Cancer Institute (NCI). Currently directed by Dr. Eric Winer,the Cancer Center brings together the resources of the Yale School of Medicine (YSM),Yale New Haven Hospital (YNHH),and the Yale School of Public Health (YSPH).
Joann G. Elmore is a professor of medicine at the David Geffen School of Medicine, professor of Health Policy and Management at the UCLA Fielding School of Public Health Director of the UCLA National Clinician Scholars Program, the endowed chair in Health Care Delivery for The Rosalind and Arthur Gilbert Foundation,and a practicing physician. She publishes studies on diagnostic accuracy of cancer screening and medical tests in addition to AI/machine learning,using computer-aided tools to aid in the early detection process of high-risk cancers Previously,she held faculty and leadership positions at the University of Washington,Fred Hutchinson Research Center,Group Health Research Institute,Yale University and was the Associate Director and member of the National Advisory Committee for the Robert Wood Johnson Clinical Scholars Program at Yale and University of Washington. Elmore received her medical degree from the Stanford University School of Medicine,residency training in internal medicine at Yale-New Haven Hospital,with advanced epidemiology training from the Yale School of Epidemiology and Public Health and the RWJF Clinical Scholars Program. In addition,she was a RWJF generalist physician faculty scholar. Elmore is board certified in internal medicine and serves on many national and international committees. She is Editor in Chief for Adult Primary Care at Up-To-Date and enjoys seeing patients as a primary care internist and teaching clinical medicine to students and residents.
Katherine A. High is an American doctor-scientist who is an emeritus professor at the Perelman School of Medicine at the University of Pennsylvania. She was the co-founder,president,and chief scientific officer of Spark Therapeutics and currently serves as President of Therapeutics at AskBio. Her career has focused on pioneering work in the area of gene therapy,with many accomplishments in basic,translational,and clinical investigation in gene therapy.
Charis Eng was a Singaporean American physician-scientist and geneticist at the Cleveland Clinic,notable for identifying the PTEN gene. She was the chairwoman and founding director of the Genomic Medicine Institute of the Cleveland Clinic,founding director and attending clinical cancer geneticist of the institute's clinical component,the Center for Personalized Genetic Healthcare,and professor and vice chairwoman of the Department of Genetics and Genome Sciences at Case Western Reserve University School of Medicine.
Melissa Andrea Simon is an American clinical obstetrician/gynecologist and scientist who focuses on health equity across the lifespan. Simon is founder and director of the Center for Health Equity Transformation (CHET) in the Feinberg School of Medicine at Northwestern University in Chicago,Illinois,and founder of the Chicago Cancer Health Equity Collaborative,a National Cancer Institute comprehensive cancer partnership led by the Robert H. Lurie Comprehensive Cancer Center of Northwestern University,Northeastern Illinois University,and the University of Illinois at Chicago. She is the George H. Gardner,MD Professor of Clinical Gynecology,the Vice-Chair of Clinical Research in the Department of Obstetrics and Gynecology,tenured professor of Obstetrics and Gynecology,Preventive Medicine and Medical Social Sciences at Northwestern University Feinberg School of Medicine,and Associate Director of Community Outreach and Engagement at the Robert H. Lurie Comprehensive Cancer Center.
Allison Joan McGeer is a Canadian infectious disease specialist in the Sinai Health System,and a professor in the Department of Laboratory Medicine and Pathobiology at the University of Toronto. She also appointed at the Dalla Lana School of Public Health and a Senior Clinician Scientist at the Lunenfeld-Tanenbaum Research Institute,and is a partner of the National Collaborating Centre for Infectious Diseases. McGeer has led investigations into the severe acute respiratory syndrome outbreak in Toronto and worked alongside Donald Low. During the COVID-19 pandemic,McGeer has studied how SARS-CoV-2 survives in the air and has served on several provincial committees advising aspects of the Government of Ontario's pandemic response.
Colleen S. Kraft is an infectious disease physician,associate professor in the Department of Pathology and Laboratory Medicine,and the director of the Clinical Virology Research Laboratory at Emory University School of Medicine. In 2014,she led Emory University Hospital's effort to treat and care for Ebola virus disease patients and is currently working to address the COVID-19 pandemic in Georgia. She currently serves on Georgia's COVID-19 task force.
Valerie Ellen Stone is an American physician who is a professor of medicine at the Harvard Medical School. She serves as Vice Chair for Diversity,Equity,and Inclusion,Department of Medicine,Brigham and Women's Hospital. She specializes in the management of HIV/AIDS,health disparities and improving the quality of medical education.
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The Confusion Assessment Method (CAM) is a diagnostic tool developed to allow physicians and nurses to identify delirium in the healthcare setting. It was designed to be brief and based on criteria from the third edition-revision of the Diagnostic and Statistical Manual of Mental Disorders (DSM-III-R). The CAM rates four diagnostic features,including acute onset and fluctuating course,inattention,disorganized thinking,and altered level of consciousness. The CAM requires that a brief cognitive test is performed before it is completed. It has been translated into more than 20 languages and adapted for use across multiple settings.
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