Signum Biosciences, Inc. is a dietary supplement company located in Boulder, Colorado.
Signum was founded in 2003 by Maxwell Stock and his father Jeffrey B. Stock in Monmouth Junction, NJ. [1] In 2020 the company relocated to Boulder, Colorado. [2]
Signum agreed in 2019 to stop making certain claims about its EHT supplement, and to stop allowing its multi-level marketing partner firm Neora (formerly Nerium International) to make such claims.
In 2015 Signum partnered with Neora, LLC (then known as Nerium International) to launch a dietary supplement called eicosanoyl-5-hydroxytryptamide (EHT). [3] EHT is derived from coffee and inhibits demethylation of the enzyme protein phosphatase 2 (PPP2CA; PP2A). [4] In October 2019 the Federal Trade Commission won a permanent injunction against Signum BioSciences, Signum Nutralogix, and affiliated companies including Neora. The injunction prohibits claims or representations of EHT's efficacy in treating or mitigating Alzheimer's disease, Parkinson's disease, or brain injury including CTE and concussion, unless those claims are backed up by randomized, double-blind, placebo-controlled human clinical testing. [5] [6]
Amway is an American multi-level marketing (MLM) company that sells health, beauty, and home care products. The company was founded in 1959 by Jay Van Andel and Richard DeVos and is based in Ada, Michigan. Amway and its sister companies under Alticor reported sales of $8.9 billion in 2019. It is the largest multi-level marketing company in the world by revenue. It conducts business through a number of affiliated companies in more than a hundred countries and territories.
A pyramid scheme is a business model that recruits members via a promise of payments or services for enrolling others into the scheme, rather than supplying investments or sale of products. As recruiting multiplies, recruiting becomes quickly impossible, and most members are unable to profit; as such, pyramid schemes are unsustainable and often illegal.
Nootropics are numerous natural, semi-synthetic and synthetic molecules which purportedly improve cognitive functions.
Herbalife Nutrition Ltd., also called Herbalife International, Inc. or simply Herbalife, is a global multi-level marketing (MLM) corporation that develops and sells dietary supplements. The company has been alleged to have fraudulently operated a pyramid scheme. Some products sold by Herbalife have caused acute hepatitis. The business is incorporated in the Cayman Islands, with its corporate headquarters located in Los Angeles, California.
Kevin Trudeau is an American author, salesman, and convicted fraudster known for promotion of his books and resulting legal cases involving the US Federal Trade Commission. His ubiquitous late-night infomercials, which promoted unsubstantiated health, diet, and financial advice, earned him a fortune but resulted in civil and criminal penalties for fraud, larceny, and contempt of court.
Vinpocetine is a synthetic derivative of the vinca alkaloid vincamine, differing by the removal of a hydroxyl group. Vincamine is extracted from either the seeds of Voacanga africana or the leaves of Vinca minor.
Brain training is a program of regular activities purported to maintain or improve one's cognitive abilities. The phrase “cognitive ability” usually refers to components of fluid intelligence such as executive function and working memory. Cognitive training reflects a hypothesis that cognitive abilities can be maintained or improved by exercising the brain, analogous to the way physical fitness is improved by exercising the body. Cognitive training activities can take place in numerous modalities such as cardiovascular fitness training, playing online games or completing cognitive tasks in alignment with a training regimen, playing video games that require visuospatial reasoning, and engaging in novel activities such as dance, art, and music.
Multi-level marketing (MLM), also called network marketing or pyramid selling, is a controversial marketing strategy for the sale of products or services in which the revenue of the MLM company is derived from a non-salaried workforce selling the company's products or services, while the earnings of the participants are derived from a pyramid-shaped or binary compensation commission system.
ConsumerLab.com, LLC. is a privately held American company registered in White Plains, NY. It is a publisher of test results on health, wellness, and nutrition products. Consumer Labs is not a laboratory, but contracts studies to outside testing laboratories. It purchases dietary supplement products and other consumer goods directly from public storefronts and online retailers, contracts for testing by private laboratories, and publishes reports based on the results. It primarily derives revenue from the sale of subscriptions to its online publications, which are paywalled. Other sources of revenue include a proprietary certification program, licensing fees, contents re-publication license fees, and advertising.
MonaVie is a defunct, American multi-level marketing company that manufactured and distributed products made from blended fruit juice concentrates, powders, and purées. The company was the subject of several controversies. Health claims for its products had not been scientifically confirmed or approved by regulatory authorities, and its chairman had been previously involved in false health claims concerning another beverage company. According to Forbes, MonaVie's business plan resembled a pyramid scheme. In 2015, the company defaulted on a US$182 million loan and went into foreclosure. Florida-based Jeunesse Global took over MonaVie’s assets when it purchased the note for $15 million.
Liquid oxygen supplements are products that claim to add extra oxygen to the human body, most often through a chemical process in the digestive system, like the breakdown of hydrogen peroxide or magnesium peroxide. While the FDA describes these products as being inert, and has penalized some producers who made explicit medical claims, it has not prohibited their sale.
Seasilver is the trademarked name of a commercial dietary supplement produced and sold by the companies Seasilver USA, Inc. and Americaloe, Inc.
Market America is a multi-level marketing company founded in 1992 by JR and Loren Ridinger. Headquartered in Greensboro, North Carolina, the company employed around 800 people as of 2016. The products offered by the company include household cleaning supplies, jewelry, personal care products, auto care, cosmetics, dietary supplements, custom websites, water purifiers, and weight management products. A 2017 lawsuit accused the company of being an illegal pyramid scheme.
Vemma Nutrition Company was a privately held multi-level marketing company that sold dietary supplements. The company was shut down in 2015 by the FTC for engaging in deceptive practices and pyramid scheming.
TINA.org (TruthinAdvertising.org) is an independent, non-profit, advertising watchdog organization. TINA.org was founded in 2012 and received its initial funding from Karen Pritzker and Michael Vlock through their Seedlings Foundation, which supports programs that nourish the physical and mental health of children and families, and fosters an educated and engaged citizenship. TINA.org is headed by Bonnie Patten, who has served as its Executive Director since its founding.
Green coffee extract is an extract of unroasted, green coffee beans. It is used in the Swiss water process for decaffeinating coffee. It has also been used as a weight-loss supplement and as an ingredient in other weight-loss products, although there is insufficient clinical evidence that it is effective or safe for such uses. In 2014, one of the primary trials showing benefit was retracted and the company that sponsored the study, Applied Food Sciences, was fined by the Federal Trade Commission for making baseless weight-loss claims using the flawed study. Green coffee extract can also be prepared as an infusion from green coffee beans.
LearningRx is a franchise based in Colorado Springs, Colorado. The company claims to improve cognitive abilities.
Federal Trade Commission v. Vemma Nutrition Company, No. 2:15-cv-01578, was a case heard in United States District Court for the District of Arizona. On August 17, 2015, the Federal Trade Commission for the United States filed a complaint for the preliminary injunction and for other equitable relief of Vemma Nutrition Company.. The FTC, under Section 13(b) of the Federal Trade Commission Act filed for the permanent injunction of Vemma and alleged Vemma in violation of Section 5(a) of the FTC Act, 15 U.S.C § 45 (a) in connection with the advertising, marketing, promotion, and sale of opportunities to sell health and wellness drinks. The FTC alleged Vemma Nutrition Company of running an illegal pyramid scheme dependent on targeting young adults and recruitment tactics that emphasize the importance of becoming an "affiliate" and purchasing "affiliate packs" and monthly auto-delivery supply packs. Vemma further emphasizes the importance of affiliates to recruit others and "teach them to duplicate this process," offering "bonuses" as incentive for doing so. Vemma CEO Benson K. Boreyko claimed in his recruitment presentations that there is a potential for affiliates to "earn up to $50,000 a month working part time." The FTC found that affiliates are unlikely to earn substantial income and suffer, therefore being misled to participate in a deceptive act in violation of Section 5(a) of the FTC Act, 15 U.S.C § 45 (a).