Related Research Articles
Heredity, also called inheritance or biological inheritance, is the passing on of traits from parents to their offspring; either through asexual reproduction or sexual reproduction, the offspring cells or organisms acquire the genetic information of their parents. Through heredity, variations between individuals can accumulate and cause species to evolve by natural selection. The study of heredity in biology is genetics.
The modern synthesis was the early 20th-century synthesis of Charles Darwin's theory of evolution and Gregor Mendel's ideas on heredity into a joint mathematical framework. Julian Huxley coined the term in his 1942 book, Evolution: The Modern Synthesis. The synthesis combined the ideas of natural selection, Mendelian genetics, and population genetics. It also related the broad-scale macroevolution seen by palaeontologists to the small-scale microevolution of local populations.
Twin studies are studies conducted on identical or fraternal twins. They aim to reveal the importance of environmental and genetic influences for traits, phenotypes, and disorders. Twin research is considered a key tool in behavioral genetics and in related fields, from biology to psychology. Twin studies are part of the broader methodology used in behavior genetics, which uses all data that are genetically informative – siblings studies, adoption studies, pedigree, etc. These studies have been used to track traits ranging from personal behavior to the presentation of severe mental illnesses such as schizophrenia.
Mutationism is one of several alternatives to evolution by natural selection that have existed both before and after the publication of Charles Darwin's 1859 book On the Origin of Species. In the theory, mutation was the source of novelty, creating new forms and new species, potentially instantaneously, in sudden jumps. This was envisaged as driving evolution, which was thought to be limited by the supply of mutations.
Dmitry Konstantinovich Belyayev was a Soviet geneticist and academician who served as director of the Institute of Cytology and Genetics (IC&G) of the USSR Academy of Sciences, Novosibirsk, from 1959 to 1985. His decades-long effort to breed domesticated silver foxes was described by The New York Times as “arguably the most extraordinary breeding experiment ever conducted.” A 2010 article in Scientific American stated that Belyayev “may be the man most responsible for our understanding of the process by which wolves were domesticated into our canine companions.”
Monoamine oxidase A, also known as MAO-A, is an enzyme that in humans is encoded by the MAOA gene. This gene is one of two neighboring gene family members that encode mitochondrial enzymes which catalyze the oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin. A mutation of this gene results in Brunner syndrome. This gene has also been associated with a variety of other psychiatric disorders, including antisocial behavior. Alternatively spliced transcript variants encoding multiple isoforms have been observed.
Brunner syndrome is a rare genetic disorder associated with a mutation in the MAOA gene. It is characterized by lower than average IQ, problematic impulsive behavior, sleep disorders and mood swings. It was identified in fourteen males from one family in 1993. It has since been discovered in additional families.
Dorret I. Boomsma is a Dutch biological psychologist specializing in genetics and twin studies.
Hans van Abeelen was the first Dutch behaviour geneticist. He obtained his M.Sc from the University of Groningen and his Ph.D. from the Catholic University of Nijmegen in 1965, where he stayed for the rest of his career as "wetenschappelijk hoofdmedewerker". He was a founding member of the Behavior Genetics Association and was a member-at-large of its executive committee from 1984 till 1987. He also served on the editorial board of its journal, Behavior Genetics, from its creation in 1971 to 1992. Van Abeelen took early retirement in 1991, but nevertheless became one of the founding members of the International Behavioural and Neural Genetics Society. Over the span of his career, he published 64 articles and book chapters and edited a book, The Genetics of Behaviour, which was an early overview of European behaviour genetics.
In multivariate quantitative genetics, a genetic correlation is the proportion of variance that two traits share due to genetic causes, the correlation between the genetic influences on a trait and the genetic influences on a different trait estimating the degree of pleiotropy or causal overlap. A genetic correlation of 0 implies that the genetic effects on one trait are independent of the other, while a correlation of 1 implies that all of the genetic influences on the two traits are identical. The bivariate genetic correlation can be generalized to inferring genetic latent variable factors across > 2 traits using factor analysis. Genetic correlation models were introduced into behavioral genetics in the 1970s–1980s.
David William Fulker was a British behavioural geneticist at the University of Colorado's Institute for Behavioral Genetics. Among positions of esteem, he was elected president of the Behavior Genetics Association (1982), and was executive editor of the society's journal Behavior Genetics. In honour of this role, the society maintains an annual Fulker Award, for the best paper in the journal each year, and for which the award is "$1000 and a decent bottle of wine".
Ambidirectional dominance occurs in a situation where multiple genes influence a phenotype and dominance is in different directions depending on the gene. For example, for gene A increased height is dominant, while for gene B decreased height is dominant. The opposite situation, where all genes show dominance in the same direction, is called directional dominance. In the same example, for both genes A and B increased height is dominant. According to Broadhurst, ambidirectional dominance is the result of stabilising selection in the evolutionary past. Ambidirectional dominance has been found for exploratory behaviours in mice and paradise fish.
Behavioural genetics, also referred to as behaviour genetics, is a field of scientific research that uses genetic methods to investigate the nature and origins of individual differences in behaviour. While the name "behavioural genetics" connotes a focus on genetic influences, the field broadly investigates the extent to which genetic and environmental factors influence individual differences, and the development of research designs that can remove the confounding of genes and environment. Behavioural genetics was founded as a scientific discipline by Francis Galton in the late 19th century, only to be discredited through association with eugenics movements before and during World War II. In the latter half of the 20th century, the field saw renewed prominence with research on inheritance of behaviour and mental illness in humans, as well as research on genetically informative model organisms through selective breeding and crosses. In the late 20th and early 21st centuries, technological advances in molecular genetics made it possible to measure and modify the genome directly. This led to major advances in model organism research and in human studies, leading to new scientific discoveries.
Wim E. Crusio is a Dutch behavioral neurogeneticist and a directeur de recherche with the French National Centre for Scientific Research in Talence, France.
Developed by Calvin S. Hall, the open field test is an experimental test used to assay general locomotor activity levels, anxiety, and willingness to explore in animals in scientific research. However, the extent to which behavior in the open field measures anxiety is controversial. The open field test can be used to assess memory by evaluating the ability of the animal to recognize a stimulus or object. Another animal test that is used to assess memory using that same concept is the novel object recognition test.
Lindon J. Eaves (1944–2022) was a behavior geneticist and priest who published on topics as diverse as the heritability of religion and psychopathology. His research encompassed the development of mathematical models reflecting competing theories of the causes and familial transmission of human human differences, the design of studies for the resolution, analytical methods for parameter estimation and hypothesis-testing and application to substantive questions about specific (human) traits. He was the first to consider standardized variance components for heritability estimates and was the first to consider the effects of living with a relative on the behavior of a person. Furthermore, he was the first to think about genotype x age interaction and set up the algebra to study the effects of genes working in males as well as females, making it possible to use twins pairs of opposite-sex. Together with Nick Martin, he wrote many classic papers, one of which is "The genetic analysis of covariance structure". They also wrote the book, Genes, culture and personality: An empirical approach. In 2012, a Festschrift was held in Edinburgh dedicated to Eaves' work; the proceedings were subsequently published in Behavior Genetics.
Classical genetics is the branch of genetics based solely on visible results of reproductive acts. It is the oldest discipline in the field of genetics, going back to the experiments on Mendelian inheritance by Gregor Mendel who made it possible to identify the basic mechanisms of heredity. Subsequently, these mechanisms have been studied and explained at the molecular level.
Social learning refers to learning that is facilitated by observation of, or interaction with, another animal or its products. Social learning has been observed in a variety of animal taxa, such as insects, fish, birds, reptiles, amphibians and mammals.
Alexander ("Lex") Rudolf Cools was a Dutch behavioral pharmacologist.
Jan K. Buitelaar is a Dutch medical doctor, psychiatrist, author, and academic. He is a professor of psychiatry and child and adolescent psychiatry at Radboud University Medical Centre and former Head of Child and Adolescent Psychiatry at Karakter Child and Adolescent Psychiatry.
References
- ↑ J.M.L. Kerbusch, 1974. Genetic analysis of exploratory behaviour, simple learning behaviour and cerebral AChE and ChE activities in mice by means of the diallel method. Ph.D. thesis, Catholic University of Nijmegen, The Netherlands, 63 + 32 pp.
- 1 2 Crusio, W.E. (1991). "Obituary Sjeng Kerbusch (1947-1991)". Behavior Genetics. 21 (5): 431–432. doi: 10.1007/BF01066721 . S2CID 148069790.
- ↑ "Historical table of BGA Meetings". Home page. Behavior Genetics Association . Retrieved 2012-10-26.
| International | |
|---|---|
| National | |
| Academics | |
