Stephanie Cragg

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Stephanie Cragg
SJCragg B&W.jpg
Alma mater University of Cambridge
University of Oxford
Scientific career
Institutions University of Oxford

Stephanie J. Cragg is a British physiologist who is Professor of Neuroscience at the University of Oxford. [1] She holds a joint appointment [2] [3] as Professor in the Department of Physiology, Anatomy and Genetics, University of Oxford and as a Fellow (Official Student), Director of Studies and Tutor for Medicine at the college Christ Church, Oxford. [2]

Contents

Early life and education

Cragg studied Natural Sciences at Clare College, University of Cambridge, followed by a DPhil in neuropharmacology at the Department of Pharmacology, University of Oxford and Lincoln College, Oxford. [3] Her graduate supervisors were Baroness Professor Susan Greenfield (Oxford) and Dr Margaret Rice (New York University). [4]

Research and career

Cragg is a neuroscientist at the University of Oxford. In her early postdoctoral research career, she was an E.P. Abraham Junior Research Fellow at St. Cross College, then an E.P. Abraham Research Fellow at Keble College, then received a Beit Memorial Fellowship followed by a Paton Research Fellowship from the Department of Pharmacology, University of Oxford. [3] She was a visiting scientist at New York University Depts of Physiology & Biophysics, and Neurosurgery, and at the University of North Carolina at Chapel Hill.

Her work focusses on understanding the functioning in health and disease of the brain's dopamine circuits and related cell types that become dysregulated in Parkinson's disease, addictions and other neurological and neuropsychiatric disorders. [2] [3] This work focusses particularly on the regulation of dopaminergic transmission.

Cragg's work includes the study of how dopamine release in the striatum is regulated by other neuronal pathways and neuromodulators, including the neurotransmitters acetylcholine, GABA, adenosine, and dysregulation in Parkinson's disease. [5] [6] Some of her most cited work relates to the axonal regulation of dopamine transmission by acetylcholine, cholinergic interneurons and nicotinic acetylcholine receptors (nAChRs). [7] [8]

Scientific leadership

Scientific journals

Societies

Engagement with scientific societies include:

Keynote lectures

References

  1. ↑ "Recognition of Distinction: Successful applicants 2014" Archived 16 September 2015 at the Wayback Machine , The University of Oxford Gazette, no. 5076, 6 November 2014. Retrieved 20 November 2016.
  2. 1 2 3 "Professor Stephanie Cragg | Christ Church, University of Oxford". www.chch.ox.ac.uk. Retrieved 18 October 2023.
  3. 1 2 3 4 "Stephanie Cragg". www.dpag.ox.ac.uk. Retrieved 18 October 2023.
  4. ↑ Helmreich, Dana L. (July 2018). "Profiles of Women in Science: Prof. Stephanie Cragg of the University of Oxford, Oxford, UK". European Journal of Neuroscience. 48 (2): 1723–1727. doi:10.1111/ejn.14058. PMID   29968289 . Retrieved 18 October 2023.
  5. ↑ Roberts, Bradley M.; Doig, Natalie M.; Brimblecombe, Katherine R.; Lopes, Emanuel F.; Siddorn, Ruth E.; Threlfell, Sarah; Connor-Robson, Natalie; Bengoa-Vergniory, Nora; Pasternack, Nicholas; Wade-Martins, Richard; Magill, Peter J.; Cragg, Stephanie J. (2 October 2020). "GABA uptake transporters support dopamine release in dorsal striatum with maladaptive downregulation in a parkinsonism model". Nature Communications. 11 (1): 4958. Bibcode:2020NatCo..11.4958R. doi: 10.1038/s41467-020-18247-5 . PMC   7532441 . PMID   33009395.
  6. ↑ Cramb, Kaitlyn M L; Beccano-Kelly, Dayne; Cragg, Stephanie J; Wade-Martins, Richard (1 August 2023). "Impaired dopamine release in Parkinson's disease". Brain. 146 (8): 3117–3132. doi: 10.1093/brain/awad064 . PMC   10393405 . PMID   36864664.
  7. ↑ Threlfell, Sarah; Lalic, Tatjana; Platt, Nicola J.; Jennings, Katie A.; Deisseroth, Karl; Cragg, Stephanie J. (July 2012). "Striatal Dopamine Release Is Triggered by Synchronized Activity in Cholinergic Interneurons". Neuron. 75 (1): 58–64. doi: 10.1016/j.neuron.2012.04.038 . PMID   22794260.
  8. ↑ Rice, Margaret E; Cragg, Stephanie J (June 2004). "Nicotine amplifies reward-related dopamine signals in striatum". Nature Neuroscience. 7 (6): 583–584. doi:10.1038/nn1244. PMID   15146188.
  9. ↑ "Addiction Neuroscience | Journal | ScienceDirect.com by Elsevier". www.sciencedirect.com.
  10. ↑ "Editors & Editorial Board". ACS Publications.
  11. ↑ "npj Parkinson's Disease". Nature. 10 July 2023. Retrieved 18 October 2023.
  12. ↑ "About". MMiN. Retrieved 18 October 2023.
  13. ↑ "Parkinson's UK College of Experts". Parkinson's UK. Retrieved 18 October 2023.
  14. ↑ "Feature Plenary Lecture, FENS Forum 2018".
  15. ↑ "Speakers". VIDA 2020.
  16. ↑ "Webinar Recordings".
  17. ↑ "Plenary Lectures".
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