Organ transplantation is a medical procedure in which an organ is removed from one body and placed in the body of a recipient, to replace a damaged or missing organ. The donor and recipient may be at the same location, or organs may be transported from a donor site to another location. Organs and/or tissues that are transplanted within the same person's body are called autografts. Transplants that are recently performed between two subjects of the same species are called allografts. Allografts can either be from a living or cadaveric source.
Liver transplantation or hepatic transplantation is the replacement of a diseased liver with the healthy liver from another person (allograft). Liver transplantation is a treatment option for end-stage liver disease and acute liver failure, although availability of donor organs is a major limitation. The most common technique is orthotopic transplantation, in which the native liver is removed and replaced by the donor organ in the same anatomic position as the original liver. The surgical procedure is complex, requiring careful harvest of the donor organ and meticulous implantation into the recipient. Liver transplantation is highly regulated, and only performed at designated transplant medical centers by highly trained transplant physicians and supporting medical team. The duration of the surgery ranges from 4 to 18 hours depending on outcome. Favorable outcomes require careful screening for eligible recipient, as well as a well-calibrated live or cadaveric donor match.
Cholecystectomy is the surgical removal of the gallbladder. Cholecystectomy is a common treatment of symptomatic gallstones and other gallbladder conditions. In 2011, cholecystectomy was the eighth most common operating room procedure performed in hospitals in the United States. Cholecystectomy can be performed either laparoscopically, or via an open surgical technique.
A Klatskin tumor is a cholangiocarcinoma occurring at the confluence of the right and left hepatic bile ducts. The disease was named after Gerald Klatskin, who in 1965 described 15 cases and found some characteristics for this type of cholangiocarcinoma
Microsurgery is a general term for surgery requiring an operating microscope. The most obvious developments have been procedures developed to allow anastomosis of successively smaller blood vessels and nerves which have allowed transfer of tissue from one part of the body to another and re-attachment of severed parts. Microsurgical techniques are utilized by several specialties today, such as general surgery, ophthalmology, orthopedic surgery, gynecological surgery, otolaryngology, neurosurgery, oral and maxillofacial surgery, plastic surgery, podiatric surgery and pediatric surgery.
Hepatectomy is the surgical resection of the liver. While the term is often employed for the removal of the liver from a liver transplant donor, this article will focus on partial resections of hepatic tissue and hepatoportoenterostomy.
Surgical Outcomes Analysis & Research, SOAR, is a research laboratory of the Department of Surgery at Boston University School of Medicine and Boston Medical Center with expertise in outcomes research. SOAR investigates surgical diseases and perioperative outcomes. The group focuses on pancreatic cancer, other gastrointestinal and hepatobiliary malignancies, vascular disease, and transplant surgery. SOAR's goal is to examine quality, delivery, and financing of care in order to have an immediate impact on patient care and system improvements. The group members utilize national health services and administrative databases, as well as institutional databases, to investigate and to address factors contributing to disease outcomes and healthcare disparities.
Secondary sclerosing cholangitis (SSC) is a chronic cholestatic liver disease. SSC is a sclerosing cholangitis with a known cause. Alternatively, if no cause can be identified, then primary sclerosing cholangitis is diagnosed. SSC is an aggressive and rare disease with complex and multiple causes. It is characterized by inflammation, fibrosis, destruction of the biliary tree and biliary cirrhosis. It can be treated with minor interventions such as continued antibiotic use and monitoring, or in more serious cases, laparoscopic surgery intervention, and possibly a liver transplant.
The Institute of Liver and Biliary Sciences (ILBS) is a mono-superspeciality hospital for liver and biliary diseases located at New Delhi, India. It has been established by the Government of the National Capital Territory (NCT) of Delhi as an autonomous Institute, under the Societies Registration Act - 1860, at New Delhi with Shiv Kumar Sarin as its founding director. ILBS is a teaching hospital and has been given the status of Deemed University by the University Grants Commission (UGC) of India. ILBS has been created by the Government of Delhi to make it a dedicated international center of excellence for the diagnosis and management of liver and biliary diseases and to provide advanced training and research in the field of Hepato-biliary Sciences.
Dr. Arvinder Singh Soin is the Chief Hepatobiliary and Liver Transplant Surgeon & Chairman of the Institute of Liver Transplantation and Regenerative Medicine, Medanta-The Medicity, India. A surgeon and pioneer in the field of liver transplantation, acknowledged for his work in establishing liver transplantation in India. Dr. Soin also runs the Liver Transplant institute at the Sir H. N. Reliance Foundation Hospital, Mumbai. Dr Soin has performed more than 3500 living donor liver transplants in India, which is the highest in the country, and the second-highest in the world.
Sander S. Florman is an American transplant surgeon and Director of the Recanati/Miller Transplantation Institute at The Mount Sinai Hospital in New York City. He is a member of the American Society of Transplant Surgeons, the American Hepato-Pancreato-Biliary Association, the American Society of Transplantation and the American College of Surgeons.
Christoph Broelsch was a German surgeon and former high school teacher. Broelsch pioneered the liver transplant surgery, when he performed the first successful liver transplant on a child in 1989.
Sarbeswar Sahariah is an Indian nephrologist and organ transplant specialist, known for his expertise in renal and pancreatic transplantation. He was honoured by the Government of India, in 2014, by bestowing on him the Padma Shri, the fourth highest civilian award, for his contributions to the field of medicine. Sahariah is credited with more than 3000 renal transplantations, which many consider, has made him the most prolific kidney transplant surgeon in the country.
J. Michael Henderson is an American general and transplant surgeon, with experience in portal hypertension, liver transplantation, and pancreatic disease. Henderson is the Chief Medical Officer at the University of Mississippi Medical Center since 2015. Prior to this role, he was with the Cleveland Clinic from 1992–2014. He was the Chairman of the Department of General Surgery and Director of the Transplant Center for 12 years, and was the Chief Quality Officer for the Cleveland Clinic’s 10-hospital system for eight years.
Saumitra Rawat is an Indian surgical gastroenterologist and the head of Surgical Gastroenterology and Liver Transplant at Sir Ganga Ram Hospital, New Delhi. The Government of India honoured him in 2015 with the award of Padma Shri.
Samiran Nundy is an Indian gastrointestinal surgeon, medical academic, writer and the President of All India Institute of Medical Sciences, Rishikesh. He is a former member of the faculty at the Cambridge University, London University and Harvard University, and is the founder editor of the National Medical Journal of India and Tropical Gastroenterology. The Government of India awarded him the fourth-highest Indian civilian honour of Padma Shri in 1985.
Narmada Prasad Gupta is an Indian urologist, medical researcher, writer and the chairman of Academics and Research Division Urology at the Medanta, the Medicity, New Delhi. He is credited with over 10,000 urological surgical procedures and the highest number of urology robotics (URobotic) surgeries in India. He is a former head of the department of urology of the All India Institute of Medical Sciences Delhi and a former president of the Urological Society of India. He received the Dr. B. C. Roy Award, the highest Indian award in the medical category, from the Medical Council of India in 2005. The government of India awarded him the fourth highest civilian honour of the Padma Shri, in 2007, for his contributions to Indian medicine.
Chen Chao-long is a Taiwanese transplant surgeon.
Giriraj Singh Bora is an Indian liver transplant surgeon. He is the founder member of the Liver Transplant Society of India. Bora was the first surgeon to successfully transplant a liver in Rajasthan. He carried out the first deceased donor and the first living donor liver transplants in Rajasthan and has been instrumental in starting a liver transplant program in the region. He currently serves as the joint director of Liver Transplantation and senior consultant of Gastrointestinal Surgery at Artemis Hospital.
James Michael Millis is an American academic and surgeon specializing in pediatric and adult liver transplantation. He is Professor of Surgery and Vice Chair of Global Surgery at University of Chicago. He is also the director of Clinical Leadership Development Fellowship and Hepatobiliary Surgery at the University of Chicago Medical Center. He is known for developing new techniques of liver surgery that improved outcomes following liver transplantation and non transplant liver and biliary tract surgery.
