Susan J. Baserga

Susan Baserga
Baserga receiving the 2016 American Society for Biochemistry and Molecular Biology William C. Rose Award
Alma mater	Yale College Yale School of Medicine Yale University
Scientific career
Institutions	Yale School of Medicine

Susan J. Baserga is an American physician who is the William H. Fleming Professor of Molecular Biophysics and Biochemistry at Yale University. Her research considers the molecular basis of ribosomes, and the mechanistic basis of inherited human disease.

Early life and education

Baserga's father, Renato Baserga, was a pathologist and cancer researcher. ^[1] In 1977, Baserga became inspired by pre-RNA splicing. As an MD–PhD candidate, Baserga studied nonsense-mediated decay mammalian cells. She moved to Joan A. Steitz's laboratory at Yale University, where she started working on ribosome biogenesis.^{[ citation needed ]}

Research and career

Baserga started her academic career at Yale in 1993. She was promoted to professor in 2007.^{[ citation needed ]} Her research sought to identify how ribosome production is regulated in mammalian cells. She uses Xenopus tropicalis as a model system for ribosomopathies, and is interested in Fanconi anemia repair factors. ^[1]

In 2020, Baserga was named the William H. Fleming Professor of Molecular Biophysics and Biochemistry. ^[2] She is the Chair of the American Society for Biochemistry and Molecular Biology Women in Biochemistry and Molecular Biology Committee. ^[3] In 2023, she joined the National Academies of Sciences, Engineering, and Medicine Committee on RNA modifications, "Towards Sequencing and Mapping of RNA Modifications". ^[4]

Awards and honors

• 2014 Charles W. Bohmfalk Prize ^[5]
• 2016 American Society for Biochemistry and Molecular Biology William C. Rose Award ^[6]
• 2018 Connecticut Technology Council Women of Innovation Category Winner in Research Innovation and Leadership ^[7]
• 2018 National Academy of Inventors ^[8]
• 2023 Elected Fellow of the American Society for Biochemistry and Molecular Biology ^[9]
• 2023 Elected to the National Academy of Medicine ^[10]
• 2024 Elected as a Member of the American Academy of Arts and Sciences

Selected publications

• François Dragon; Jennifer E G Gallagher; Patricia A Compagnone-Post; et al. (27 June 2002). "A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis". Nature . 417 (6892): 967–70. doi:10.1038/NATURE00769. ISSN   1476-4687. PMID   12068309. Wikidata   Q27937306.
• John L. Woolford, Jr.; Susan J Baserga (1 November 2013). "Ribosome biogenesis in the yeast Saccharomyces cerevisiae". Genetics . 195 (3): 643–681. doi:10.1534/GENETICS.113.153197. ISSN   0016-6731. PMC   3813855 . PMID   24190922. Wikidata   Q37269766.
• Yvonne N Osheim; Sarah L French; Kristin M Keck; Erica A Champion; Krasimir Spasov; François Dragon; Susan J Baserga; Ann L Beyer (1 December 2004). "Pre-18S ribosomal RNA is structurally compacted into the SSU processome prior to being cleaved from nascent transcripts in Saccharomyces cerevisiae". Molecular Cell . 16 (6): 943–954. doi:10.1016/J.MOLCEL.2004.11.031. ISSN   1097-2765. PMID   15610737. Wikidata   Q30435434.

References

1. "Dr. Susan Baserga". www.rnasociety.org. Retrieved 2023-10-13.
2. "Professorship for Baserga; Bryant honored; remembering Ohnishi". www.asbmb.org. Retrieved 2023-10-13.
3. "Susan J. Baserga". www.asbmb.org. Retrieved 2023-10-13.
4. "Okafor recognized; Baserga joins group; award for Bollinger". www.asbmb.org. Retrieved 2023-10-13.
5. "Dr. Susan Baserga Wins the Charles W. Bohmfalk Prize for Teaching". medicine.yale.edu. Retrieved 2023-10-13.
6. "Dr. Susan Baserga wins William C. Rose Award". YaleNews. 2016-03-21. Retrieved 2023-10-13.
7. "Yale's Baserga recognized by Connecticut Technology Council". YaleNews. 2018-04-05. Retrieved 2023-10-13.
8. Hathaway, Bill (2018-12-11). "Yale's Baserga named to National Academy of Inventors". YaleNews. Retrieved 2023-10-13.
9. "Professor Baserga elected as 2023 ASBMB Fellow". medicine.yale.edu. Retrieved 2023-10-13.
10. "National Academy of Medicine Elects New Members From Yale". medicine.yale.edu. Retrieved 2023-10-12.