On November 20,2018,the Diamondbacks added Clarke to their 40-man roster to protect him from the Rule 5 draft.[10] He opened the 2019 season with Reno. On April 20,he was recalled to the major league roster for the first time.[11] He made his major league debut that afternoon versus the Chicago Cubs,recording three scoreless innings in relief and earning a save.[12] His first big-league win came on May 25 at Oracle Park against the San Francisco Giants. He finished the season with a record of 5–5 in 23 games (15 starts).
Clarke joined a small group of Major League pitchers who picked up a win,loss and save in their first three appearances. In 2020,Clarke pitched to a 4.36 ERA with 40 strikeouts in 43.1 innings pitched across 12 appearances (5 starts).[13]
Clarke made 43 appearances out of the bullpen for the Diamondbacks in 2021,registering a 4.98 ERA with 39 strikeouts across 43+1⁄3 innings pitched. On November 30, 2021, he was non-tendered by the Diamondbacks, making him a free agent.[14]
Kansas City Royals
On December 1, 2021, Clarke signed a major league contract with the Kansas City Royals.[15] In 47 appearances for the Royals in 2022, he registered a 4.04 ERA with 48 strikeouts and 3 saves across 49.0 innings of work.[16]
Clarke made 58 appearances for Kansas City in 2023, posting a 5.95 ERA with 65 strikeouts and 3 saves across 59.0 innings pitched.[17]
Milwaukee Brewers
On December 14, 2023, the Royals traded Clarke to the Milwaukee Brewers in exchange for minor leaguers Cam Devanney and Ryan Brady.[18] On March 30, 2024, Clarke underwent surgery to repair a torn meniscus in his right knee, ruling him out for 6–8 weeks.[19] He was designated for assignment following the acquisition of Aaron Civale on July 3.[20] Clarke cleared waivers and was sent outright to the Triple–A Nashville Sounds on July 7.[21] He elected free agency on October 9.[22]
Kansas City Royals (second stint)
On December 12, 2024, Clarke signed a minor league contract with the Kansas City Royals.[23] He began the 2025 season with the Triple-A Omaha Storm Chasers, recording a 4.40 ERA with nine strikeouts over 10 games. On May 1, 2025, the Royals selected Clarke's contract, adding him to their active roster.[24] He made 51 appearances during the regular season, compiling a 1-1 record and 3.25 ERA with 44 strikeouts and one save across 55+1⁄3 innings pitched. On November 21, Clarke was non-tendered by Kansas City and became a free agent.[25]
Arizona Diamondbacks (second stint)
On January 15, 2026, Clarke signed a one-year, $1.55 million contract with the Arizona Diamondbacks.[26]
Personal life
Clarke was born with paralysis of the muscles on the right side of his face.[27]
Clarke and his wife, also named Taylor, have twin sons together.[28]
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