Thync is a venture-backed startup that developed a non-invasive, neurostimulation technology that targets the autonomic nervous system. The company launched the first electronic wearable device to increase energy and lower stress in 2015. Its makers claim the device works by neurostimulation techniques such as TENS. In 2017, Thync exited the consumer health market and focused all efforts on the development of a bioelectronic therapy to treat moderate psoriasis.
A wearable computer, also known as a wearable or body-borne computer, is a small computing device worn on the body.
Transcranial magnetic stimulation (TMS), also known as repetitive transcranial magnetic stimulation (rTMS), is a noninvasive form of brain stimulation in which a changing magnetic field is used to cause electric current at a specific area of the brain through electromagnetic induction. An electric pulse generator, or stimulator, is connected to a magnetic coil, which in turn is connected to the scalp. The stimulator generates a changing electric current within the coil which induces a magnetic field; this field then causes a second inductance of inverted electric charge within the brain itself.
Johnson & Johnson is an American multinational corporation founded in 1886 that develops medical devices, pharmaceutical and consumer packaged goods. Its common stock is a component of the Dow Jones Industrial Average and the company is ranked No. 37 on the 2018 Fortune 500 list of the largest United States corporations by total revenue. J&J is one of the world's most valuable companies.
Abbott Laboratories is an American medical devices and health care company with headquarters in the Abbott Park Business Center in Lake Bluff, Illinois, United States. The company was founded by Chicago physician Wallace Calvin Abbott in 1888 to formulate known drugs; today, it sells medical devices, diagnostics, branded generic medicines and nutritional products. It split off the research-based pharmaceuticals into AbbVie in 2013.
Cranial electrotherapy stimulation (CES) is a form of neurostimulation that delivers a small, pulsed, alternating current via electrodes on the head. CES is used with the intention of treating a variety of conditions such as anxiety, depression and insomnia. CES has been suggested as a possible treatment for headaches, fibromyalgia, smoking cessation, and opiate withdrawal, but there is little evidence of effectiveness for many of these conditions and the evidence for use in acute depression is not sufficient to justify it.
Medtronic plc is a medical device company that generates the majority of its sales and profits from the U.S. healthcare system but is headquartered in the Republic of Ireland for tax purposes. Medtronic has an operational and executive headquarters in Fridley, Minnesota in the U.S. In 2015, Medtronic acquired Irish–tax registered Covidien, in the largest U.S. corporate tax inversion in history, which enabled Medtronic to move its legal registration from the U.S. to Ireland. Medtronic operates in 140 countries and employs over 86,000 people.
Brain implants, often referred to as neural implants, are technological devices that connect directly to a biological subject's brain – usually placed on the surface of the brain, or attached to the brain's cortex. A common purpose of modern brain implants and the focus of much current research is establishing a biomedical prosthesis circumventing areas in the brain that have become dysfunctional after a stroke or other head injuries. This includes sensory substitution, e.g., in vision. Other brain implants are used in animal experiments simply to record brain activity for scientific reasons. Some brain implants involve creating interfaces between neural systems and computer chips. This work is part of a wider research field called brain-computer interfaces.
Motorola Mobility LLC, marketed as simply Motorola, is a consumer electronics and telecommunications company owned by Chinese technology firm Lenovo. The company primarily manufactures smartphones and other mobile devices running the Android operating system developed by Google.
Hospira was an American global pharmaceutical and medical device company with headquarters in Lake Forest, Illinois. It had approximately 19,000 employees. Before its acquisition by Pfizer, Hospira was the world's largest producer of generic injectable pharmaceuticals, manufacturing generic acute-care and oncology injectables, as well as integrated infusion therapy and medication management systems. Hospira's products are used by hospitals and alternate site providers, such as clinics, home healthcare providers and long-term care facilities. It was formerly the hospital products division of Abbott Laboratories. On September 3, 2015, Hospira was acquired by Pfizer, who subsequently sold off the medical devices portion of Hospira to ICU Medical.
A Spinal Cord Stimulator (SCS) or Dorsal Column Stimulator (DCS) is a type of implantable neuromodulation device that is used to send electrical signals to select areas of the spinal cord for the treatment of certain pain conditions. SCS is a consideration for people who have a pain condition that has not responded to more conservative therapy.
Khosla Ventures is an American venture capital firm founded by Vinod Khosla, focused on early stage companies in the Internet, computing, mobile, silicon technology, biotechnology, healthcare and clean technology sectors.
Responsive neurostimulation device or RNS system is a neurostimulation system designed to prevent epileptic seizures.
Yossi Gross is an Israeli engineer, inventor and entrepreneur. He is a founding partner of Rainbow Medical, an operational investment company, established to launch companies based on the technological ideas and inventions of Gross. Yossi Gross first started his professional career in the 20th century as a project manager of the Lavi program for the Israel Air Force. From the 1990s through to the beginning of the 21st century, Gross started 27 medical device companies based on his various inventions in electronics, signal processing, nanotechnology, drug delivery and neurostimulation. Gross's various companies have developed or are currently developing treatments for diabetes, gastroenterology, stroke, ophthalmology, asthma, congestive heart failure, and urology. Gross has 567 filed patents.
Sarah H. Lisanby is an American psychiatrist who studies the use of neurostimulation devices to treat mental illness. Since 2015 she has directed the division of the National Institute of Mental Health(NIMH) working on translational research.
Preventive treatment of migraines can be an important component of migraine management. Such treatments can take many forms, including everything from surgery, taking certain drugs or nutritional supplements, to lifestyle alterations such as increased exercise and avoidance of migraine triggers.
The Dash is a device manufactured by Sony that connected using Wi-Fi to the Internet. It had a touch screen which the user could use to browse information or listen to music. It was not a portable device since it did not have an internal battery. It was positioned as a personal internet viewer which could act as an alarm clock, Internet radio, digital photo frame and many other uses. It had applications which were downloaded onto the device. These were the same as those supported by the Chumby device.
Neurostimulation is the purposeful modulation of the nervous system's activity using invasive or non-invasive means. Neurostimulation usually refers to the electromagnetic approaches to neuromodulation.
The Barnes & Noble Nook is a brand of e-readers developed by American book retailer Barnes & Noble, based on the Android platform. The original device was announced in the U.S. in October 2009, and was released the next month. The original Nook had a six-inch E-paper display and a separate, smaller color touchscreen that serves as the primary input device and was capable of Wi-Fi and AT&T 3G wireless connectivity. The original nook was followed in November 2010 by a color LCD device called the Nook Color, in June 2011 by the Nook Simple Touch, and in November 2011 and February 2012 by the Nook Tablet. On April 30, 2012, Barnes & Noble entered into a partnership with Microsoft that spun off the Nook and college businesses into a subsidiary. On August 28, 2012, Barnes and Noble announced partnerships with retailers in the UK, which began offering the Nook digital products in October 2012. In December 2014, B&N purchased Microsoft's Nook shares, ending the partnership.
Neuromodulation is "the alteration of nerve activity through targeted delivery of a stimulus, such as electrical stimulation or chemical agents, to specific neurological sites in the body". It is carried out to normalize – or modulate – nervous tissue function. Neuromodulation is an evolving therapy that can involve a range of electromagnetic stimuli such as a magnetic field (rTMS), an electric current, or a drug instilled directly in the subdural space. Emerging applications involve targeted introduction of genes or gene regulators and light (optogenetics), and by 2014, these had been at minimum demonstrated in mammalian models, or first-in-human data had been acquired. The most clinical experience has been with electrical stimulation.
Muse is a wearable brain sensing headband. The device measures brain activity via 4 electroencephalography (EEG) sensors. An accompanying mobile app converts the EEG signal into audio feedback that is fed to the user via headphones. Muse is manufactured by InteraXon, a company based in Toronto, Ontario, Canada that was founded in 2007 by Ariel Garten, Trevor Coleman, Chris Aimone, and Steve Mann originally at 330 Dundas Street West, in Toronto, Ontario, Canada. Development of the Muse product began in 2003, and after several rounds of fundraising, was released to the public in May 2014. In 2018, the company launched Muse 2, which also measures heart rate, breath, and body movement.