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Lyme disease, also known as Lyme borreliosis, is a tick-borne disease caused by species of Borrelia bacteria, transmitted by blood-feeding ticks in the genus Ixodes. The most common sign of infection is an expanding red rash, known as erythema migrans (EM), which appears at the site of the tick bite about a week afterwards. The rash is typically neither itchy nor painful. Approximately 70–80% of infected people develop a rash. Early diagnosis can be difficult. Other early symptoms may include fever, headaches and tiredness. If untreated, symptoms may include loss of the ability to move one or both sides of the face, joint pains, severe headaches with neck stiffness or heart palpitations. Months to years later, repeated episodes of joint pain and swelling may occur. Occasionally, shooting pains or tingling in the arms and legs may develop.
Tick-borne diseases, which afflict humans and other animals, are caused by infectious agents transmitted by tick bites. They are caused by infection with a variety of pathogens, including rickettsia and other types of bacteria, viruses, and protozoa. The economic impact of tick-borne diseases is considered to be substantial in humans, and tick-borne diseases are estimated to affect ~80 % of cattle worldwide. Most of these pathogens require passage through vertebrate hosts as part of their life cycle. Tick-borne infections in humans, farm animals, and companion animals are primarily associated with wildlife animal reservoirs. Many tick-borne infections in humans involve a complex cycle between wildlife animal reservoirs and tick vectors. The survival and transmission of these tick-borne viruses are closely linked to their interactions with tick vectors and host cells. These viruses are classified into different families, including Asfarviridae, Reoviridae, Rhabdoviridae, Orthomyxoviridae, Bunyaviridae, and Flaviviridae.
Ixodes holocyclus, commonly known as the Australian paralysis tick, is one of about 75 species in the Australian tick fauna and is considered the most medically important. It can cause paralysis by injecting neurotoxins into its host. It is usually found in a 20-kilometre wide band following the eastern coastline of Australia. Within that range, Ixodes holocyclus is the tick most frequently encountered by humans and their pets. Because the same area includes Australia's most densely populated regions, bites on people, pets and livestock are relatively common.
Babesia, also called Nuttallia, is an apicomplexan parasite that infects red blood cells and is transmitted by ticks. Originally discovered by Romanian bacteriologist Victor Babeș in 1888; over 100 species of Babesia have since been identified.
Kirsten Elizabeth Gillibrand is an American lawyer and politician serving as the junior United States senator from New York since 2009. A member of the Democratic Party, she served as member of the U.S. House of Representatives from 2007 to 2009.
The Infectious Diseases Society of America (IDSA) is a medical association representing physicians, scientists, and other healthcare professionals who specialize in infectious diseases. It was founded in 1963 and is based in Arlington, Virginia. As of 2018, IDSA had more than 11,000 members from across the United States and nearly 100 other countries on six different continents. IDSA's purpose is to improve the health of individuals, communities, and society by promoting excellence in patient care, education, research, public health, and prevention relating to infectious diseases. It is a 501(c)(6) organization.
A canine vector-borne disease (CVBD) is one of "a group of globally distributed and rapidly spreading illnesses that are caused by a range of pathogens transmitted by arthropods including ticks, fleas, mosquitoes and phlebotomine sandflies." CVBDs are important in the fields of veterinary medicine, animal welfare, and public health. Some CVBDs are of zoonotic concern.
Allen Caruthers Steere is an American rheumatologist. He is a professor of rheumatology at Harvard University and previously at Tufts University and Yale University. Steere and his mentor, Stephen Malawista of Yale University, are credited with discovering and naming Lyme disease, and he has published almost 300 scholarly articles on Lyme disease during his more than 40 years of studies of this infection. At a ceremony in Hartford, Connecticut in 1998, Governor John G. Rowland declared September 24 to be "Allen C. Steere Day".
On November 7, 2006, New York, along with the rest of the country held elections for the United States House of Representatives. Democrats picked up 3 House seats, the 19th, the 20th, and the 24th.
In epidemiology, a disease vector is any living agent that carries and transmits an infectious pathogen such as a parasite or microbe, to another living organism. Agents regarded as vectors are mostly blood-sucking insects such as mosquitoes. The first major discovery of a disease vector came from Ronald Ross in 1897, who discovered the malaria pathogen when he dissected the stomach tissue of a mosquito.
Under Our Skin: The Untold Story of Lyme Disease is a 2008 film advocating for the existence of "chronic Lyme disease", a controversial and unrecognized diagnosis. The film was directed by Andy Abrahams Wilson, who became interested in the subject after his sister claimed to be afflicted by "chronic Lyme." The film had its theatrical premiere on June 19, 2009 at the IFC Center in New York City.
Borrelia miyamotoi is a bacterium of the spirochete phylum in the genus Borrelia. A zoonotic organism, B. miyamotoi can infect humans through the bite of several species of hard-shell Ixodes ticks, the same kind of ticks that spread B. burgdorferi, the causative bacterium of Lyme disease. Ixodes ticks are also the primary vector in the spread of babesiosis and anaplasmosis.
Transstadial transmission is the persistence of a symbiont or pathogen in an organism from one life stage ("stadium") to the next, such as larva to nymph to adult. This type of transmission is typically observed in insects. For example, the bacterium Borrelia burgdorferi, the causative agent for Lyme disease, infects the tick vector as a larva, with the infection maintained as the tick molts to a nymph and later develops as an adult. Transstadial transmission is also seen with other microbes such as other bacteria, fungi, and viruses in numerous insects. In addition to ticks, mites are another common vector. Transstadial transmission is especially relevant to public health, as several threats to public health are maintained in insect populations by transstadial transmission. Some debate exists regarding the classification of transstadial transmission as vertical transmission versus horizontal transmission. Reasons for this stem from further debate regarding transovarial transmission, described as the passage of a symbiont or pathogen from an infected female to its progeny, especially in eggs.
Terry W. Gipson is an American politician who was elected as a Democratic member of the New York Senate in November 2012, and served from January 1, 2013, through December 31, 2014, in the 200th State Legislature. He represented the state's 41st district, which covers most of Dutchess County and Putnam County. He launched a campaign for Governor of New York in 2017 to challenge incumbent Democrat Andrew Cuomo; Gipson withdrew from the race in 2018.
Science-Based Medicine is a website and blog with articles covering issues in science and medicine, especially medical scams and practices. Founded in 2008, it is owned and operated by the New England Skeptical Society, and run by Steven Novella and David Gorski.
Ovarian Cancer Research Alliance (OCRA) is a not-for-profit organization focused on ovarian cancer research, advocacy and patient support. The organization was formed in January 2016 when the former not-for-profit organization Ovarian Cancer Research Fund, which focused primarily on ovarian cancer research, combined with Ovarian Cancer National Alliance, which focused primarily on ovarian cancer advocacy and support programs, to form one organization.
Chronic Lyme disease (CLD) is the name used by some people with non-specific symptoms, such as fatigue, muscle pain, and cognitive dysfunction to refer to their condition, even if there is no evidence that they had Lyme disease. Both the label and the belief that these people's symptoms are caused by this particular infection are generally rejected by medical professionals. Chronic Lyme disease is distinct from post-treatment Lyme disease syndrome, a set of lingering symptoms which may persist after successful antibiotic treatment of infection with Lyme-causing Borrelia bacteria, and which may have similar symptoms to those associated with CLD.
Global climate change has increased the occurrence of some infectious diseases. Infectious diseases whose transmission is impacted by climate change include, for example, vector-borne diseases like dengue fever, malaria, tick-borne diseases, leishmaniasis, zika fever, chikungunya and Ebola. One mechanism contributing to increased disease transmission is that climate change is altering the geographic range and seasonality of the insects that can carry the diseases. Scientists stated a clear observation in 2022: "The occurrence of climate-related food-borne and waterborne diseases has increased ."
Nobel disease or Nobelitis is an informal term for the embrace of strange or scientifically unsound ideas by some Nobel Prize winners, usually later in life. It has been argued that the effect results, in part, from a tendency for Nobel winners to feel empowered by the award to speak on topics outside their specific area of expertise, although it is unknown whether Nobel Prize winners are more prone to this tendency than other individuals. Paul Nurse, co-winner of the 2001 Nobel Prize in Physiology or Medicine, warned later laureates against "believing you are expert in almost everything, and being prepared to express opinions about most issues with great confidence, sheltering behind the authority that the Nobel Prize can give you". "Nobel disease" has been described as a tongue-in-cheek term.
Lyme Disease Awareness Month is observed every May internationally, especially in countries where Lyme disease is common. Lyme disease is caused by a tick-borne parasite, and Lyme Disease Awareness Month includes initiatives aimed at prevention and early identification of possible Lyme disease cases.
References
- ↑ "About TBDA". Archived from the original on April 9, 2012. Retrieved 30 July 2013.
- ↑ "TBDA" . Retrieved 30 July 2013.
- ↑ "TBDA's David Roth on NBC New York Nightly News" . Retrieved 30 July 2013.
- ↑ "Actress Candice Accola Launches Bite Back for a Cure, Tick-Borne Disease Alliance's National Grassroots Campaign to Fight Devastating Tick-Borne Diseases" . Retrieved 30 July 2013.
- ↑ "The New Tick-Borne Disease Alliance" . Retrieved 5 August 2013.
- ↑ "Candice Accola MCs Annual Tick-Borne Disease Alliance Benefit" . Retrieved 5 August 2013.
- ↑ "U.S. Sen. Kirsten Gillibrand, U.S. Sen. Richard Blumenthal, Tick-Borne Disease Alliance (TBDA), and Weill Cornell Medical College Host NYC Forum on Silent Epidemic of Lyme and Tick-Borne Diseases on Monday, March" . Retrieved 5 August 2013.
- ↑ "Kobre named chairman of Global Lyme Alliance". Greenwich Sentinel. Greenwich, Connecticut. June 26, 2015. Retrieved 5 October 2016.
- ↑ Gorski, David. "Robert F. Kennedy, Jr. promotes an awful epidemiology study linking vaccines and neurological conditions from…Yale? | Science-Based Medicine". Science-Based Medicine. Retrieved 22 April 2021.
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