USS Oriole, 2003
|Awarded:||1 April 1991|
|Laid down:||3 August 1991|
|Launched:||22 May 1993|
|Acquired:||12 May 1995|
|Commissioned:||16 September 1995|
|Decommissioned:||30 June 2006|
|Struck:||30 June 2006|
|Fate:||Sold to Taiwan|
|Name:||ROCS Yung Jin (MHC 1310)|
|Acquired:||2 August 2012|
|Commissioned:||10 August 2012|
|Class and type:||Osprey-class coastal minehunter|
|Displacement:||796 tons (light) 882 tons (full)|
|Length:||188 ft (57 m)|
|Beam:||38 ft (12 m)|
|Draft:||11 ft (3.4 m)|
|Propulsion:||Two diesels (800 hp each)|
|Speed:||12 knots (22 km/h; 14 mph)|
|Complement:||5 officers and 46 enlisted|
|Armament:||Mine neutralization system & two .50 cal (12.7 mm) machine guns|
USS Oriole (MHC-55) was an Osprey-class coastal minehunter of the United States Navy. She was built by Intermarine USA and launched in 1993 then commissioned in 1995. After only eleven years of service she was decommissioned in 2006 and sold to Taiwan. She now operates as ROCS Yung Jin (MHC-1310).
In immunology, an antigen (Ag) is a molecule or molecular structure, such as may be present at the outside of a pathogen, that can be bound to by an antigen-specific antibody (Ab) or B cell antigen receptor (BCR). The presence of antigens in the body normally triggers an immune response. The term "antigen" originally described a structural molecule that binds specifically to an antibody only in the form of native antigen. It was expanded later to refer to any molecule or a linear molecular fragment after processing the native antigen that can be recognized by T-cell receptor (TCR). BCR and TCR are both highly variable antigen receptors diversified by somatic V(D)J recombination. Both T cells and B cells are cellular components of adaptive immunity. The Ag abbreviation stands for an antibody generator.
A T cell is a type of lymphocyte, which develops in the thymus gland and plays a central role in the immune response. T cells can be distinguished from other lymphocytes by the presence of a T-cell receptor on the cell surface. These immune cells originate as precursor cells, derived from bone marrow, and develop into several distinct types of T cells once they have migrated to the thymus gland. T cell differentiation continues even after they have left the thymus.
A cytotoxic T cell is a T lymphocyte that kills cancer cells, cells that are infected, or cells that are damaged in other ways.
The major histocompatibility complex (MHC) is a large locus on vertebrate's DNA containing a set of closely linked polymorphic genes that code for cell surface proteins essential for the adaptive immune system. This locus got its name because it was discovered in the study of tissue compatibility upon transplantation. Later studies revealed that tissues rejection due to incompatibility is an experimental artifact masking the real function of MHC molecules - binding an antigen derived from self-proteins or from pathogen and the antigen presentation on the cell surface for recognition by the appropriate T-cells. MHC molecules mediate interactions of leukocytes, also called white blood cells (WBCs), which are immune cells, with other leukocytes or with body cells. The MHC determines compatibility of donors for organ transplant, as well as one's susceptibility to an autoimmune disease via cross-reacting immunization.
An antigen-presenting cell (APC) or accessory cell is a cell that displays antigen complexed with major histocompatibility complexes (MHCs) on their surfaces; this process is known as antigen presentation. T cells may recognize these complexes using their T cell receptors (TCRs). APCs process antigens and present them to T-cells.
MHC class I molecules are one of two primary classes of major histocompatibility complex (MHC) molecules and are found on the cell surface of all nucleated cells in the bodies of vertebrates. They also occur on platelets, but not on red blood cells. Their function is to display peptide fragments of proteins from within the cell to cytotoxic T cells; this will trigger an immediate response from the immune system against a particular non-self antigen displayed with the help of an MHC class I protein. Because MHC class I molecules present peptides derived from cytosolic proteins, the pathway of MHC class I presentation is often called cytosolic or endogenous pathway.
The T-cell receptor (TCR) is a protein complex found on the surface of T cells, or T lymphocytes, that is responsible for recognizing fragments of antigen as peptides bound to major histocompatibility complex (MHC) molecules. The binding between TCR and antigen peptides is of relatively low affinity and is degenerate: that is, many TCRs recognize the same antigen peptide and many antigen peptides are recognized by the same TCR.
CD8 is a transmembrane glycoprotein that serves as a co-receptor for the T-cell receptor (TCR). Along with the TCR, the CD8 co-receptor plays a role in T cell signaling and aiding with cytotoxic T cell antigen interactions.
MYH7 is a gene encoding a myosin heavy chain beta (MHC-β) isoform expressed primarily in the heart, but also in skeletal muscles. This isoform is distinct from the fast isoform of cardiac myosin heavy chain, MYH6, referred to as MHC-α. MHC-β is the major protein comprising the thick filament in cardiac muscle and plays a major role in cardiac muscle contraction.
Herpesviridae is a large family of DNA viruses that cause infections and certain diseases in animals, including humans. The members of this family are also known as herpesviruses. The family name is derived from the Greek word herpein, referring to spreading cutaneous lesions, usually involving blisters, seen in flares of herpes simplex 1, herpes simplex 2 and herpes zoster (shingles). In 1971, the International Committee on the Taxonomy of Viruses (ICTV) established Herpesvirus as a genus with 23 viruses among four groups.
HK Martin is a professional ice hockey team in the second highest league Slovak 1. Liga in Slovakia.
Antigen presentation is a vital immune process that is essential for T cell immune response triggering. Because T cells recognise only fragmented antigens displayed on cell surfaces, antigen processing must occur before the antigen fragment, now bound to the major histocompatibility complex (MHC), is transported to the surface of the cell, a process known as presentation, where it can be recognized by a T cell receptor. If there has been an infection with viruses or bacteria, the cell will present an endogenous or exogenous peptide fragment derived from the antigen bound to MHC molecules. There are two types of MHC molecules which differ in the behaviour of the antigens: MHC class I molecules (MHC-I) bind peptides from the cell cytosol, while peptides generated in the endocytic vesicles after internalisation are bound to MHC class II (MHC-II). Cellular membranes separate these two cellular environments - intracellular and extracellular. Each T cell can finally recognise only ten to hundreds copies of a unique sequence of a single peptide among thousands of other peptides presented on the very same cell because MHC molecule in one cell can bind quite a large range of peptides.
MHC class II molecules are a class of major histocompatibility complex (MHC) molecules normally found only on professional antigen-presenting cells such as dendritic cells, mononuclear phagocytes, some endothelial cells, thymic epithelial cells, and B cells. These cells are important in initiating immune responses.
USS Kingfisher (MHC-56) was the sixth ship of Osprey-class coastal mine hunters. She is named after the kingfisher.
USS Black Hawk (MHC-58) was the eighth ship of Osprey-class coastal mine hunters.
Claus Wedekind is a Swiss biological researcher notable for his 1995 study that determined a major histocompatibility complex (MHC) dependent mate preference in humans.
USS Sanderling (AMS-35/AMCU-49/MHC-49/YMS-446/PCS-1393) was the lead ship of her subclass of YMS-1-class minesweepers built for the United States Navy during World War II.
DNA-binding protein RFX5 is a protein that in humans is encoded by the RFX5 gene.
DNA-binding protein RFXANK is a protein that in humans is encoded by the RFXANK gene.
The Stanley Cup, then named the Dominion Hockey Challenge Cup, was first awarded in 1893 to the Montreal Hockey Club of the Amateur Hockey Association of Canada (AHAC) at the end of the 1893 AHAC season for having placed first in the standings with a 7–1–0 record. The season ended on March 17, but Montreal was officially presented with the trophy on May 15.
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