Scientific misconduct is the violation of the standard codes of scholarly conduct and ethical behavior in the publication of professional scientific research. It is violation of scientific integrity: violation of the scientific method and of research ethics in science, including in the design, conduct, and reporting of research.
The National Institutes of Health, commonly referred to as NIH, is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late 1880s and is now part of the United States Department of Health and Human Services. Many NIH facilities are located in Bethesda, Maryland, and other nearby suburbs of the Washington metropolitan area, with other primary facilities in the Research Triangle Park in North Carolina and smaller satellite facilities located around the United States. The NIH conducts its own scientific research through the NIH Intramural Research Program (IRP) and provides major biomedical research funding to non-NIH research facilities through its Extramural Research Program.
The United States Department of Health and Human Services (HHS) is a cabinet-level executive branch department of the U.S. federal government created to protect the health of the U.S. people and providing essential human services. Its motto is "Improving the health, safety, and well-being of America". Before the separate federal Department of Education was created in 1979, it was called the Department of Health, Education, and Welfare (HEW).
The United States Public Health Service is a collection of agencies of the Department of Health and Human Services concerned with public health, containing nine out of the department's twelve operating divisions. The Assistant Secretary for Health oversees the PHS. The Public Health Service Commissioned Corps (PHSCC) is the federal uniformed service of the PHS, and is one of the eight uniformed services of the United States.
The National Institute of Mental Health (NIMH) is one of 27 institutes and centers that make up the National Institutes of Health (NIH). The NIH, in turn, is an agency of the United States Department of Health and Human Services and is the primary agency of the United States government responsible for biomedical and health-related research.
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is one of the institutes and centers that make up the National Institutes of Health, an agency of the United States Department of Health and Human Services (HHS).
The regulation of science refers to use of law, or other ruling, by academic or governmental bodies to allow or restrict science from performing certain practices, or researching certain scientific areas.
Eric T. Poehlman, is an American scientist, formerly researching in the field of human obesity and aging. In 2000, Poehlman was investigated for scientific misconduct; the case continued for several years and in 2005, he admitted to fraudulent research practices. He had published research using falsified and fabricated data in studies on aging metabolism and obesity, including purporting to show beneficial effects on lipid profiles and abdominal fat in menopausal women being treated with hormone therapy. Poehlman became the first academic in the United States to be jailed for falsifying data in a grant application.
The Agency for Healthcare Research and Quality is one of twelve agencies within the United States Department of Health and Human Services (HHS). The agency is headquartered in North Bethesda, Maryland, a suburb of Washington, D.C.. It was established as the Agency for Health Care Policy and Research (AHCPR) in 1989 as a constituent unit of the Public Health Service (PHS) to enhance the quality, appropriateness, and effectiveness of health care services and access to care by conducting and supporting research, demonstration projects, and evaluations; developing guidelines; and disseminating information on health care services and delivery systems.
Thereza Imanishi-Kari is an associate professor of pathology at Tufts University. Her research focuses on the origins of autoimmune diseases, particularly systemic lupus erythematosus, studied using mice as model organisms. Previously she had been a faculty member at the Massachusetts Institute of Technology. She is notable for her role in what became known as the "Baltimore affair", in which a 1986 paper she co-authored with David Baltimore was the subject of research misconduct allegations. Following a series of investigations, she was fully exonerated of the charges in 1996.
Institutional Animal Care and Use Committees (IACUCs) are centrally important in applying laws about animal research in the United States. Similar systems operate in other countries, but generally under different titles; for example, in Canada a typical title would be the University Animal Care Committee (UACC), while in the United Kingdom it would be the Animal Welfare and Ethical Review Body (AWERB).
The National Institute of Biomedical Imaging and Bioengineering (NIBIB), founded at the National Institutes of Health (NIH) in 2000, is located in Bethesda, Maryland. It is one of 27 institutes and centers that are part of NIH, an agency of the U.S. Department of Health and Human Services (HHS).
Data sharing is the practice of making data used for scholarly research available to other investigators. Many funding agencies, institutions, and publication venues have policies regarding data sharing because transparency and openness are considered by many to be part of the scientific method.
The Office for Human Research Protections (OHRP) is a small office within the United States Department of Health and Human Services (DHHS), specifically the Office of the Assistant Secretary for Health in the Office of the Secretary of DHHS, that deals with ethical oversights in clinical research conducted by the department, mostly through the National Institutes of Health (NIH).
Alan R. Price is an academic who served as the associate director for investigative oversight of the Office of Research Integrity (ORI) at the National Institute of Health and the United States Public Health Service. Price's job involved reviewing the handling of allegations and reports of inquiries and investigations of scientific misconduct or research misconduct. He served 17 for years as a senior official of the Office of Research Integrity.
The Department of Defense Office of Inspector General is an independent, objective agency that provides oversight related to the programs and operations of the United States Department of Defense (DoD). DoD IG was created in 1982 as an amendment to the Inspector General Act of 1978.
The Office of Inspector General (OIG) for the United States Department of Health and Human Services (HHS) is responsible for oversight of the United States Department of Health and Human Service's approximately $2.4 trillion portfolio of programs. Approximately 1,650 auditors, investigators, and evaluators, supplemented by staff with expertise in law, technology, cybersecurity, data analytics, statistics, medicine, economics, health policy, and management and administration. Based on Federal Employee Viewpoint Survey scores, OIG has been ranked the best place to work in HHS for 5 consecutive years by the Partnership for Public Service.
The NIH Intramural Research Program (IRP) is the internal research program of the National Institutes of Health (NIH), known for its synergistic approach to biomedical science. With 1,200 Principal Investigators and over 4,000 Postdoctoral Fellows conducting basic, translational, and clinical research, the NIH Intramural Research Program is the largest biomedical research institution on earth. The unique funding environment of the IRP facilitates opportunities to conduct both long-term and high-impact science that would otherwise be difficult to undertake. With rigorous external reviews ensuring that only the most outstanding research secures funding, the IRP is responsible for many scientific accomplishments, including the discovery of fluoride to prevent tooth decay, the use of lithium to manage bipolar disorder, and the creation of vaccines against hepatitis, Hemophilus influenzae (Hib), and human papillomavirus (HPV). In addition, the IRP has also produced or trained 21 Nobel Prize-winning scientists.
Research integrity or scientific integrity is an aspect of research ethics that deals with best practice or rules of professional practice of scientists.
A Designated Member Review (DMR) or Designated Subcommittee Review (DSR), also known as Designated Review, is a review of a protocol where a committee designates one or more members of the committee to review a decisionmaking process or a protocol or procedure, a review which would ordinarily require the full committee's review. Typically this pertains to IACUCs.
