Scientific misconduct is the violation of the standard codes of scholarly conduct and ethical behavior in the publication of professional scientific research. A Lancet review on Handling of Scientific Misconduct in Scandinavian countries provides the following sample definitions, reproduced in The COPE report 1999:
The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late 1880s and is now part of the United States Department of Health and Human Services. The majority of NIH facilities are located in Bethesda, Maryland and other nearby suburbs of the Washington metropolitan area, with other primary facilities in the Research Triangle Park in North Carolina and smaller satellite facilities located around the United States. The NIH conducts its own scientific research through its Intramural Research Program (IRP) and provides major biomedical research funding to non-NIH research facilities through its Extramural Research Program.
The United States Department of Health and Human Services (HHS), is a cabinet-level executive branch department of the U.S. federal government created to protect the health of all Americans and providing essential human services. Its motto is "Improving the health, safety, and well-being of America". Before the separate federal Department of Education was created in 1979, it was called the Department of Health, Education, and Welfare (HEW).
David Baltimore is an American biologist, university administrator, and 1975 Nobel laureate in Physiology or Medicine. He is currently President Emeritus and Distinguished Professor of Biology at the California Institute of Technology (Caltech), where he served as president from 1997 to 2006. He also served as the director of the Joint Center for Translational Medicine, which joined Caltech and UCLA in a program to translate basic scientific discoveries into clinical realities. He also formerly served as president of Rockefeller University from 1990 to 1991, founder and Director of the Whitehead Institute of Biomedical Research from 1982 to 1990, and was president of the American Association for the Advancement of Science in 2007.
The National Institute of Mental Health (NIMH) is one of 27 institutes and centers that make up the National Institutes of Health (NIH). The NIH, in turn, is an agency of the United States Department of Health and Human Services and is the primary agency of the United States government responsible for biomedical and health-related research.
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is one of the institutes and centers that make up the National Institutes of Health, an agency of the United States Department of Health and Human Services (HHS).
The National Institute of Allergy and Infectious Diseases (NIAID) is one of the 27 institutes and centers that make up the National Institutes of Health (NIH), an agency of the United States Department of Health and Human Services (HHS). NIAID's mission is to conduct basic and applied research to better understand, treat, and prevent infectious, immunologic, and allergic diseases.
In the United States, Office of Inspector General (OIG) is a generic term for the oversight division of a federal or state agency aimed at preventing inefficient or unlawful operations within their parent agency. Such offices are attached to many federal executive departments, independent federal agencies, as well as state and local governments. Each office includes an inspector general and employees charged with identifying, auditing, and investigating fraud, waste, abuse, embezzlement and mismanagement of any kind within the executive department.
The regulation of science refers to use of law, or other ruling, by academic or governmental bodies to allow or restrict science from performing certain practices, or researching certain scientific areas.
The Agency for Healthcare Research and Quality is one of twelve agencies within the United States Department of Health and Human Services (HHS). The agency is headquartered in North Bethesda, Maryland, a suburb of Washington, D.C.. It was established as the Agency for Health Care Policy and Research (AHCPR) in 1989 as a constituent unit of the Public Health Service (PHS) to enhance the quality, appropriateness, and effectiveness of health care services and access to care by conducting and supporting research, demonstration projects, and evaluations; developing guidelines; and disseminating information on health care services and delivery systems.
Thereza Imanishi-Kari is an associate professor of pathology at Tufts University. Her research focuses on the origins of autoimmune diseases, particularly systemic lupus erythematosus, studied using mice as model organisms. Previously she had been a faculty member at the Massachusetts Institute of Technology. She is notable for her role in what became known as the "Baltimore affair", in which a 1986 paper she co-authored with David Baltimore was the subject of research misconduct allegations. Following a series of investigations, she was fully exonerated of the charges in 1996.
Institutional Animal Care and Use Committees (IACUCs) are centrally important in applying laws about animal research in the United States. Most research involving laboratory animals is funded by the United States National Institutes of Health or, to lesser extents, other federal agencies. The NIH Office of Laboratory Animal Welfare (OLAW) has been directed by law to develop policies that describe the role of Institutional Animal Care and Use Committees.
The National Institute of Biomedical Imaging and Bioengineering (NIBIB), founded at the National Institutes of Health (NIH) in 2000, is located in Bethesda, Maryland. It is one of 27 institutes and centers that are part of NIH, an agency of the U.S. Department of Health and Human Services (HHS).
Data sharing is the practice of making data used for scholarly research available to other investigators. Many funding agencies, institutions, and publication venues have policies regarding data sharing because transparency and openness are considered by many to be part of the scientific method.
Alan R. Price is an academic who served as the associate director for investigative oversight of the Office of Research Integrity (ORI) at the National Institute of Health and the United States Public Health Service. Price's job involved reviewing the handling of allegations and reports of inquiries and investigations of scientific misconduct or research misconduct. He served 17 for years as a senior official of the Office of Research Integrity.
The Department of Defense Inspector General (DoDIG) is an independent, objective agency that provides oversight related to the programs and operations of the United States Department of Defense (DoD). DoD IG was created in 1982 as an amendment to the Inspector General Act of 1978.
The Office of Inspector General (OIG) for the United States Department of Health and Human Services (HHS) is responsible for oversight of the HHS’s approximately $2.4 trillion portfolio of programs. Approximately 1,650 auditors, investigators, and evaluators, supplemented by staff with expertise in law, technology, cybersecurity, data analytics, statistics, medicine, economics, health policy, and management and administration. Based on Federal Employee Viewpoint Survey scores, OIG has been ranked the best place to work in HHS for 5 consecutive years by the Partnership for Public Service.
The NIH Intramural Research Program (IRP) is the internal research program of the National Institutes of Health (NIH), known for its synergistic approach to biomedical science. With 1,200 Principal Investigators and over 4,000 Postdoctoral Fellows conducting basic, translational, and clinical research, the NIH Intramural Research Program is the largest biomedical research institution on earth. The unique funding environment of the IRP facilitates opportunities to conduct both long-term and high-impact science that would otherwise be difficult to undertake. With rigorous external reviews ensuring that only the most outstanding research secures funding, the IRP is responsible for many scientific accomplishments, including the discovery of fluoride to prevent tooth decay, the use of lithium to manage bipolar disorder, and the creation of vaccines against hepatitis, Hemophilus influenzae (HIB), and human papillomavirus (HPV). In addition, the IRP has also produced or trained 21 Nobel Prize-winning scientists.
A Designated Member Review (DMR) or Designated Subcommittee Review (DSR), also knows as Designated Review, is a review of a protocol where a committee designates one or more members of the committee to review a decisionmaking process or a protocol or procedure, a review which would ordinarily require the full committee's review. Typically this pertains to IACUCs.
