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A pandemic is an epidemic of an infectious disease that has a sudden increase in cases and spreads across a large region, for instance multiple continents or worldwide, affecting a substantial number of individuals. Widespread endemic diseases with a stable number of infected individuals such as recurrences of seasonal influenza are generally excluded as they occur simultaneously in large regions of the globe rather than being spread worldwide.
Sir Peter Karel, Baron Piot is a Belgian-British microbiologist known for his research into Ebola and AIDS.
Global health is the health of populations in a worldwide context; it has been defined as "the area of study, research, and practice that places a priority on improving health and achieving equity in health for all people worldwide". Problems that transcend national borders or have a global political and economic impact are often emphasized. Thus, global health is about worldwide health improvement, reduction of disparities, and protection against global threats that disregard national borders, including the most common causes of human death and years of life lost from a global perspective.
Thomas R. Frieden is an American infectious disease and public health physician. He serves as president and CEO of Resolve to Save Lives, a $225 million, five-year initiative to prevent epidemics and cardiovascular disease.
Sir Jeremy James Farrar is a British medical researcher who has served as Chief Scientist at the World Health Organization since 2023. He was previously the director of The Wellcome Trust from 2013 to 2023 and a professor of tropical medicine at the University of Oxford.
Tedros Adhanom Ghebreyesus is an Ethiopian public health official, researcher, diplomat, and the Director-General of the World Health Organization since 2017. He is the first African to become WHO Director-General, receiving an endorsement for the role by the African Union. Tedros played a role in the response to the Ebola virus epidemic, the COVID-19 pandemic, and the 2022–2023 mpox outbreak.
A public health emergency of international concern is a formal declaration by the World Health Organization (WHO) of "an extraordinary event which is determined to constitute a public health risk to other States through the international spread of disease and to potentially require a coordinated international response", formulated when a situation arises that is "serious, sudden, unusual, or unexpected", which "carries implications for public health beyond the affected state's national border" and "may require immediate international action". Under the 2005 International Health Regulations (IHR), states have a legal duty to respond promptly to a PHEIC. The declaration is publicized by an IHR Emergency Committee (EC) of international experts, which was developed following the 2002–2004 SARS outbreak.
Disease X is a placeholder name that was adopted by the World Health Organization (WHO) in February 2018 on their shortlist of blueprint priority diseases to represent a hypothetical, unknown pathogen. The WHO adopted the placeholder name to ensure that their planning was sufficiently flexible to adapt to an unknown pathogen. Former Director of the US National Institute of Allergy and Infectious Diseases Anthony Fauci stated that the concept of Disease X would encourage WHO projects to focus their research efforts on entire classes of viruses, instead of just individual strains, thus improving WHO capability to respond to unforeseen strains.
Chikwe Ihekweazu is a Nigerian epidemiologist, public health physician and the World Health Organization's Assistant Director-General for Health Emergency Intelligence and Surveillance Systems.
The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), began with an outbreak of COVID-19 in Wuhan, China, in December 2019. Soon after, it spread to other areas of Asia, and then worldwide in early 2020. The World Health Organization (WHO) declared the outbreak a public health emergency of international concern (PHEIC) on 30 January 2020, and assessed the outbreak as having become a pandemic on 11 March.
Michael Joseph Ryan is an Irish epidemiologist and former trauma surgeon, specialising in infectious disease and public health. He is executive director of the World Health Organization's Health Emergencies Programme, leading the team responsible for the international containment and treatment of COVID-19. Ryan has held leadership positions and has worked on various outbreak response teams in the field to eradicate the spread of diseases including bacillary dysentery, cholera, Crimean–Congo hemorrhagic fever, Ebola, Marburg virus disease, measles, meningitis, relapsing fever, Rift Valley fever, SARS, and Shigellosis.
Flattening the curve is a public health strategy to slow down the spread of an epidemic, used against the SARS-CoV-2 virus during the early stages of the COVID-19 pandemic. The curve being flattened is the epidemic curve, a visual representation of the number of infected people needing health care over time. During an epidemic, a health care system can break down when the number of people infected exceeds the capability of the health care system's ability to take care of them. Flattening the curve means slowing the spread of the epidemic so that the peak number of people requiring care at a time is reduced, and the health care system does not exceed its capacity. Flattening the curve relies on mitigation techniques such as hand washing, use of face masks and social distancing.
Pandemic prevention is the organization and management of preventive measures against pandemics. Those include measures to reduce causes of new infectious diseases and measures to prevent outbreaks and epidemics from becoming pandemics. It is not to be mistaken for pandemic preparedness or mitigation which largely seek to mitigate the magnitude of negative effects of pandemics, although the topics may overlap with pandemic prevention in some respects.
Planning and preparing for pandemics has happened in countries and international organizations. The World Health Organization writes recommendations and guidelines, though there is no sustained mechanism to review countries' preparedness for epidemics and their rapid response abilities. National action depends on national governments. In 2005–2006, before the 2009 swine flu pandemic and during the decade following it, the governments in the United States, France, UK, and others managed strategic health equipment stocks, but they often reduced inventory after the 2009 pandemic in order to reduce costs.
Maria Petronella Gerarda Koopmans is a Dutch virologist who is Head of the Erasmus MC Department of Viroscience. Her research considers emerging infectious diseases, noroviruses and veterinary medicine. In 2018 she was awarded the Netherlands Organisation for Scientific Research (NWO) Stevin Prize. She serves on the scientific advisory group of the World Health Organization.
John N. Nkengasong is a Cameroonian-American virologist serving as the Global AIDS Coordinator in the Biden administration since 2022 and Senior Bureau Official for Global Health Security and Diplomacy since 2023. Dr. Nkengasong will resign at the start of the Trump administration in 2025. He previously worked as the Director of the Africa Centres for Disease Control and Prevention from 2016 to 2022, as well as at the World Health Organization (WHO) and Centers for Disease Control and Prevention. During the COVID-19 pandemic, Nkengasong was appointed the WHO Special Envoy for Africa.
Part of managing an infectious disease outbreak is trying to delay and decrease the epidemic peak, known as flattening the epidemic curve. This decreases the risk of health services being overwhelmed and provides more time for vaccines and treatments to be developed. Non-pharmaceutical interventions that may manage the outbreak include personal preventive measures such as hand hygiene, wearing face masks, and self-quarantine; community measures aimed at physical distancing such as closing schools and cancelling mass gathering events; community engagement to encourage acceptance and participation in such interventions; as well as environmental measures such surface cleaning. It has also been suggested that improving ventilation and managing exposure duration can reduce transmission.
Since the beginning of the COVID-19 pandemic, there have been efforts by scientists, governments, and others to determine the origin of the SARS-CoV-2 virus. Similar to other outbreaks, the virus was derived from a bat-borne virus and most likely was transmitted to humans via another animal in nature, or during wildlife bushmeat trade such as that in food markets. While other explanations, such as speculations that SARS-CoV-2 was accidentally released from a laboratory have been proposed, such explanations are not supported by evidence. Conspiracy theories about the virus's origin have also proliferated.
The Independent Panel for Pandemic Preparedness and Response was established by the Director-General of the World Health Organization in response to a resolution adopted in the 73rd World Health Assembly at the onset of COVID-19 pandemic. Its mission is to "provide an evidence-based path for the future", and is led by Co-Chairs Ellen Johnson Sirleaf, the former President of Liberia and Helen Clark, the former Prime Minister of New Zealand.
References
- ↑ Oltermann, Philip (September 2021). "WHO opens pandemic intelligence hub to look out for future crises | World Health Organization". The Guardian. Retrieved 2021-10-18.
- ↑ Balakrishnan, Vijay Shankar (July 2021). "WHO–Germany collaboration for pandemic intelligence research - The Lancet Microbe". The Lancet Microbe. 2 (7): e290. doi:10.1016/S2666-5247(21)00154-3. PMID 35544164 . Retrieved 2021-10-18.
- ↑ "Angela Merkel inaugurates WHO Hub for Pandemic and Epidemic Intelligence to analyse data on emerging health threats". firstpost.com. 2 September 2021. Retrieved 2021-10-18.
