Why Zebras Don't Get Ulcers

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Why Zebras Don't Get Ulcers
Why Zebras Don't Get Ulcers.jpg
Author Robert Sapolsky
CountryUS
LanguageEnglish
Subject Stress
GenreNon-fiction
Published1994
Publisher W. H. Freeman (2nd ed.), Holt Paperbacks (3rd ed.)
Pages320
ISBN 978-0-7167-3210-5

Why Zebras Don't Get Ulcers is a 1994 (2nd ed. 1998, 3rd ed. 2004) book by Stanford University biologist Robert M. Sapolsky. The book includes the subtitle "A Guide to Stress, Stress-related Diseases, and Coping" on the front cover of its third edition.

Contents

Background and synopsis

The title derives from Sapolsky's premise that for animals such as zebras, stress is generally episodic (e.g., running away from a lion), while for humans, stress is often chronic (e.g., worrying about losing one's job). [1] Therefore, many wild animals are less susceptible than humans to chronic stress-related disorders such as ulcers, hypertension, decreased neurogenesis and increased hippocampal neuronal atrophy. However, chronic stress occurs in some social primates (Sapolsky studies baboons) for individuals on the lower side of the social dominance hierarchy.

Sapolsky focuses on the effects of glucocorticoids on the human body, arguing that such hormones may be useful to animals in the wild escaping their predators, (see Fight-or-flight response ) but the effects on humans, when secreted at high quantities or over long periods of time, are much less desirable. Sapolsky relates the history of endocrinology, how the field reacted at times of discovery, and how it has changed through the years. [2] While most of the book focuses on the biological machinery of the body, the last chapter of the book focuses on self-help.

Why Zebras Don't Get Ulcers argues that social phenomena such as child abuse and the chronic stress of poverty affect biological stress, leading to increased risk of disease and disability.

Reception

The book received mostly positive reviews. Kirkus Reviews called it an "entertaining explanation of how stress affects the body and what we can do to counteract its effects." [3] Barry Keverne wrote in a review for New Scientist : "Everyone can benefit from reading Why Zebras Don't Get Ulcers and gain insights into the workings of the body and mind, and why some of us are more vulnerable than others to stress-related illness." [1]

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<span class="mw-page-title-main">Stress (biology)</span> Organisms response to a stressor such as an environmental condition or a stimulus

Stress, whether physiological, biological or psychological, is an organism's response to a stressor such as an environmental condition. Stress is the body's method of reacting to a condition such as a threat, challenge or physical and psychological barrier. There are two hormones that an individual produces during a stressful situation, well known as adrenaline and cortisol. There are two kinds of stress hormone levels. Resting (basal) cortisol levels are normal everyday quantities that are essential for standard functioning. Reactive cortisol levels are increases in cortisol in response to stressors. Stimuli that alter an organism's environment are responded to by multiple systems in the body. In humans and most mammals, the autonomic nervous system and hypothalamic-pituitary-adrenal (HPA) axis are the two major systems that respond to stress.

<span class="mw-page-title-main">Fight-or-flight response</span> Physiological reaction to a perceived threat or harmful event

The fight-or-flight or the fight-flight-freeze-or-fawn is a physiological reaction that occurs in response to a perceived harmful event, attack, or threat to survival. It was first described by Walter Bradford Cannon. His theory states that animals react to threats with a general discharge of the sympathetic nervous system, preparing the animal for fighting or fleeing. More specifically, the adrenal medulla produces a hormonal cascade that results in the secretion of catecholamines, especially norepinephrine and epinephrine. The hormones estrogen, testosterone, and cortisol, as well as the neurotransmitters dopamine and serotonin, also affect how organisms react to stress. The hormone osteocalcin might also play a part.

<span class="mw-page-title-main">Robert Sapolsky</span> American endocrinologist (born 1957)

Robert Morris Sapolsky is an American neuroendocrinology researcher and author. He is a professor of biology, neurology, neurological sciences, and neurosurgery at Stanford University. He is also a research associate at the National Museums of Kenya.

<i>A Primates Memoir</i> 2001 book by Robert Sapolsky

A Primate's Memoir: A Neuroscientist's Unconventional Life Among the Baboons is a 2001 book by the American biologist Robert Sapolsky. The book documents Sapolsky's years in Kenya studying baboons as a graduate student. The chapters alternate between describing observations of a troop of baboons and the wildly different culture in Africa that he is increasingly cognizant of. The book portrays an unconventional way of studying neurophysiology to determine the effects of stress on life expectancy.

<i>The Third Chimpanzee</i> 1991 book by Jared Diamond

The Third Chimpanzee: The Evolution and Future of the Human Animal is a 1991 book by academic and popular science author Jared Diamond, in which the author explores concepts relating to the animal origins of human behavior. The book follows a series of articles published by Diamond, a physiologist, examining the evidence and its interpretation in earlier treatments of the related species, including cultural characteristics or features often regarded as particularly unique to humans. The book was released in the United Kingdom in 1991 by Radius under the title The Rise and Fall of the Third Chimpanzee: How Our Animal Heritage Affects the Way We Live and in the United States in 1992 by HarperCollins under the title The Third Chimpanzee: The Evolution and Future of the Human Animal. In 2014, Diamond published an adapted version for young people with Seven Stories Press titled, The Third Chimpanzee for Young People.

Allostasis (/ˌɑːloʊˈsteɪsɪs/) is a physiological mechanism of regulation in which the human body anticipates and adjusts its energy use according to environmental demands. First proposed by Peter Sterling and Joseph Eyer in 1988, the concept of allostasis shifts the focus away from the body maintaining a rigid internal set-point, as in homeostasis, to the brain's ability and role to interpret environmental stress and coordinate changes in the body using neurotransmitters, hormones, and other signaling mechanisms. Allostasis is believed to be not only involved in the body's stress response and adaptation to chronic stress; it may also have a role in the regulation of the immune system as well as in the development of chronic diseases such as hypertension and diabetes.

<span class="mw-page-title-main">Allostatic load</span> Wear and tear on the body due to stress

Allostatic load is "the wear and tear on the body" which accumulates as an individual is exposed to repeated or chronic stress. The term was coined by Bruce McEwen and Eliot Stellar in 1993. It represents the physiological consequences of chronic exposure to fluctuating or heightened neural or neuroendocrine response which results from repeated or prolonged chronic stress.

Phenoptosis is a conception of the self-programmed death of an organism proposed by Vladimir Skulachev in 1999.

Chronic stress is the physiological or psychological response induced by a long-term internal or external stressor. The stressor, either physically present or recollected, will produce the same effect and trigger a chronic stress response. There is a wide range of chronic stressors, but most entail relatively prolonged problems, conflicts and threats that people encounter on a daily basis. And several chronic stressors, including "neighbourhood environment, financial strain, interpersonal stress, work stress and caregiving.", have been identified as associated with disease and mortality.

In social psychology, social defeat is the negative experience of being excluded from the majority group. The term is used in the study of the physiological and behavioral effects of hostile interactions among either animals or humans, in either a dyadic or in a group-individual context, potentially greatly affecting control over resources, access to mates, and social positions.

Animal psychopathology is the study of mental or behavioral disorders in non-human animals.

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<span class="mw-page-title-main">Psychological stress</span> Feeling of strain and pressure

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References

  1. 1 2 "Review: How fear eats the soul". New Scientist. Retrieved 19 December 2021.
  2. "Book Review-Why Zebras Don't Get Ulcers – The Physical Impact of Stress". Thor Projects. 12 December 2016. Retrieved 19 December 2021.
  3. "Why Zebras Don't Get Ulcers". Kirkus reviews. Retrieved 19 December 2021.