William D. Spotnitz | |
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Education | Harvard University, BS Columbia University, MD University of Florida, MBA |
Employer | University of Virginia Health System |
William D. Spotnitz is a cardiothoracic surgeon and medical researcher who has made significant contributions to the development and testing of surgical techniques. He is a notable researcher in the United States in use of fibrin glue (a surgical adhesive used to create hemostasis [1] ). [2] Spotnitz serves as a heart surgeon in the University of Virginia Health System. [3] [4] He also previously served as the director of the hospital's Tissue Adhesive Center, [5] [6] which promoted and advanced the use of adhesives in surgery. [7] He currently serves as the director of the Surgical Therapeutic Advancement Center, a successor program conducting more generalized research in surgical procedures. [8]
Spotnitz earned his bachelor's in chemistry from Harvard University and his medical degree from Columbia University College of Physicians and Surgeons. In 2007, he earned an MBA from the University of Florida. [9] For his contributions in the “development of tissue adhesives for surgical use”, Spotnitz was inducted into the 2004 class of the College of Fellows of the American Institute for Medical and Biological Engineering. [10]
Cauterization is a medical practice or technique of burning a part of a body to remove or close off a part of it. It destroys some tissue in an attempt to mitigate bleeding and damage, remove an undesired growth, or minimize other potential medical harm, such as infections when antibiotics are unavailable.
Phalloplasty is the construction or reconstruction of a penis or the artificial modification of the penis by surgery. The term is also occasionally used to refer to penis enlargement.
In biology, hemostasis or haemostasis is a process to prevent and stop bleeding, meaning to keep blood within a damaged blood vessel. It is the first stage of wound healing. This involves coagulation, which changes blood from a liquid to a gel. Intact blood vessels are central to moderating blood's tendency to form clots. The endothelial cells of intact vessels prevent blood clotting with a heparin-like molecule and thrombomodulin, and prevent platelet aggregation with nitric oxide and prostacyclin. When endothelium of a blood vessel is damaged, the endothelial cells stop secretion of coagulation and aggregation inhibitors and instead secrete von Willebrand factor, which initiate the maintenance of hemostasis after injury. Hemostasis involves three major steps:
Breast augmentation and augmentation mammoplasty is a cosmetic surgery technique using breast-implants and fat-graft mammoplasty techniques to increase the size, change the shape, and alter the texture of the breasts. Augmentation mammoplasty is applied to correct congenital defects of the breasts and the chest wall. As an elective cosmetic surgery, primary augmentation changes the aesthetics – of size, shape, and texture – of healthy breasts.
An implant is a medical device manufactured to replace a missing biological structure, support a damaged biological structure, or enhance an existing biological structure. Medical implants are man-made devices, in contrast to a transplant, which is a transplanted biomedical tissue. The surface of implants that contact the body might be made of a biomedical material such as titanium, silicone, or apatite depending on what is the most functional. In some cases implants contain electronics, e.g. artificial pacemaker and cochlear implants. Some implants are bioactive, such as subcutaneous drug delivery devices in the form of implantable pills or drug-eluting stents.
An antihemorrhagic (antihæmorrhagic) agent is a substance that promotes hemostasis. It may also be known as a hemostatic agent.
Robotic surgery are types of surgical procedures that are done using robotic systems. Robotically assisted surgery was developed to try to overcome the limitations of pre-existing minimally-invasive surgical procedures and to enhance the capabilities of surgeons performing open surgery.
Adhesions are fibrous bands that form between tissues and organs, often as a result of injury during surgery. They may be thought of as internal scar tissue that connects tissues not normally connected.
TachoSil is a collagen sponge coated with the human coagulation factors fibrinogen and thrombin. It is used during surgery to stop local bleeding on internal organs (hemostasis). The sponge is manufactured from horse tendons. TachoSil reacts upon contact with blood, other body fluids or saline to form a clot that glues it to the tissue surface. Hemostasis is reached in a few minutes, and the sponge is absorbed by the body within several weeks.
Pterygium refers to any wing-like triangular membrane occurring in the neck, eyes, knees, elbows, ankles or digits.
Fibrin glue is a surgical formulation used to create a fibrin clot for hemostasis, cartilage repair surgeries or wound healing. It contains separately packaged human fibrinogen and human thrombin.
A fibrin scaffold is a network of protein that holds together and supports a variety of living tissues. It is produced naturally by the body after injury, but also can be engineered as a tissue substitute to speed healing. The scaffold consists of naturally occurring biomaterials composed of a cross-linked fibrin network and has a broad use in biomedical applications.
A barrier membrane is a device used in oral surgery and periodontal surgery to prevent epithelium, which regenerates relatively quickly, from growing into an area in which another, more slowly growing tissue type, such as bone, is desired. Such a method of preventing epithelial migration into a specific area is known as guided tissue regeneration (GTR).
Dermal fibroblasts are cells within the dermis layer of skin which are responsible for generating connective tissue and allowing the skin to recover from injury. Using organelles, dermal fibroblasts generate and maintain the connective tissue which unites separate cell layers. Furthermore, these dermal fibroblasts produce the protein molecules including laminin and fibronectin which comprise the extracellular matrix. By creating the extracellular matrix between the dermis and epidermis, fibroblasts allow the epithelial cells of the epidermis to affix the matrix, thereby allowing the epidermal cells to effectively join together to form the top layer of the skin.
A surgical sealant film is an implantable medical device used during surgery. It is a preformed flexible patch that is applied to supplement sutures and surgical staples to seal tissues and prevent leaks of fluid and air.
Tissuemed is a medical device developer and manufacturer based in Leeds, UK.
Glued intraocular lens or glued IOL is a surgical technique for implantation of a posterior chamber IOL with the use of biological glue in eyes with deficient or absent posterior capsules. A quick-acting surgical fibrin sealant derived from human blood plasma, with both hemostatic and adhesive properties, is used.
Surgical knots (ligatures) are the knots used to bind suture materials together while binding tissue in surgery. They are used in medical and veterinary settings.
Alexey Nikolaevich Severtsev – a Russian doctor of medicine sciences, professor in the hospital surgery department of the medical faculty in Pirogov Russian National Research Medical University and the chief surgeon of a chain of clinics “MEDSI”.
Postoperative wounds are those wounds acquired during surgical procedures. Postoperative wound healing occurs after surgery and normally follows distinct bodily reactions: the inflammatory response, the proliferation of cells and tissues that initiate healing, and the final remodeling. Postoperative wounds are different from other wounds in that they are anticipated and treatment is usually standardized depending on the type of surgery performed. Since the wounds are 'predicted' actions can be taken beforehand and after surgery that can reduce complications and promote healing.