William N. Sullivan (June 23, 1908 - March 2, 1979) was an American entomologist who is widely credited with co-inventing the aerosol bomb or "bug bomb," with Lyle D. Goodhue, while employed by the United States Department of Agriculture. [1] [2] The "bug bomb" was developed for aircraft disinsection through the dispersion of insecticide for controlling mosquitoes. The invention proved invaluable in the Pacific Theater during World War II where it was used extensively to control the spread of insect borne disease - primarily malaria - which was causing far more casualties than actual combat. [3] [4]
Sullivan was born on June 23, 1908, in Lawrence, Massachusetts, one of eight children born to Katherine (Lynch) and William N. Sullivan, Sr. between 1898 and 1910. Three of his siblings died at young ages; Katherine as a toddler of unknown causes, Frances as an infant of whooping cough, and Mary at age 20 of tuberculosis.
William received his early education in the public schools of Lawrence, graduating from Lawrence High School in 1926. He earned a Bachelor of Science degree in 1930 from Massachusetts Agricultural College (MAC), now the University of Massachusetts Amherst and then a Master of Science degree (Entomology Major) in 1939, also from the University of Massachusetts Amherst. William was a member of the Reserve Officers' Training Corps (ROTC) as an undergraduate student at Massachusetts Agriculture College, and he was commissioned as a 2nd Lieutenant in the U.S. Army 3rd Cavalry Division, Reserves at graduation.
William N. Sullivan never married and had no children.
The majority of Sullivan's career was with the United States Department of Agriculture (May 18, 1931 - May 5, 1942, and July 21, 1947 - June 30, 1978). He served in the United States Army Air Force during and after World War II (May 5, 1942 - July 21, 1947), entering as a commissioned 1st Lieutenant and rising to Major before being honorably discharged.
In the late 1930s, the first of Sullivan's scientific innovations occurred as a result of his interest in the emergence of global air transportation and the possible damage that aircraft travel could do by spreading insects dangerous to humans, crops, and animals. At that time, a crude hand sprayer was used to disperse a solution of pyrethrum in kerosene with the hope of killing some of the insect hitchhikers. Sullivan joined with Dr. Lyle D. Goodhue, an accomplished chemist, to develop improved methods for disinsecting aircraft. Theirs first effort involved burning a mixture of pyrethrum, corn stalks, and sodium nitrate in the presence of house flies. The kill was satisfactory, but too much of the insecticide was destroyed by burning. Dripping the solution on the heated surface of a hotplate gave better results, and splashing was overcome by spraying the solution on a hotplate. The heat produced a fine mist or aerosol that was 20 times more effective against house flies than the original burning method. This principle was widely used in "fogging machines" to control mosquitoes in urban areas, but it was not a practical way for disinsecting aircraft.
Goodhue and Sullivan subsequently experimented with a mixture of pyrethrum, sesame oil, and Freon 12 (Dichlorodifluoromethane) placed in a 5 lb. carbon dioxide cylinder equipped with a valve and an oil burner nozzle. When the tank was inverted and the valve opened, the solution was sprayed out under the vapor pressure of Freon 12, which is 82 lbs./sq. in. at 20 deg. C. The Freon immediately evaporated and left the insecticide dispersed in the air as an aerosol. Goodhue and Sullivan now had a method of dispersing insecticides that was simple, highly effective against mosquitoes, nonflammable, and nonstaining; exactly the qualities that they were seeking in aircraft disinsection. The U.S. Patent Office subsequently granted Goodhue and Sullivan a patent (#2,321,023) on this invention which was assigned to the Secretary of Agriculture. [5]
The breadboard model, as the original patented aerosol was referred to, was excellent for demonstrations, but unsuitable for use in the field. In the jungles of the South Pacific, malaria alone incapacitated eight times as many troops as combat. Sullivan was commissioned into the U.S. Army Air Force and assigned to the Army Medical Center, Walter Reed Hospital. The commanding officer there was familiar with the aerosol development, and secured his transfer to the Aero-Medical Laboratory, Wright-Patterson Air Force Base to develop a suitable insecticidal aerosol container for use by troops in the field. At Wright Field, a representative of Westinghouse Electric Co. and Lt. Sullivan evolved the idea of modifying the 1-lb Freon container used for home refrigerators for use as the aerosol dispenser. The prototype was promising, but the rubber stopper that was used to seal the container between uses was found to leak. This difficulty was overcome by using a metal screw cap, and the World War II "aerosol bomb" was born. Within three months of Sullivan's arrival at Wright Field, the first order of 150,000 aerosol bombs went out. With this order began the manufacture of over 40 million aerosol bombs during World War II for military use.
Sullivan was attached to the Air Transport Command, after three months at Wright Field, and assigned to train personnel in the use of the newly developed aerosol insecticide at U.S. air bases serving the North Africa and India theaters,. During the tour of duty, he traveled throughout British West Africa, North Africa and Karachi, India (now part of Pakistan), in charge of disinsection of U.S. planes to prevent their carrying the malaria-bearing anopheles Gambia mosquito and other insects to South American air bases. After 18 months of service overseas, he was transferred to the Army Air Force Center at Orlando, FL, to develop methods of controlling mosquitoes in jungle areas by airplane spraying. In July 1946 he served as a radiological monitor on atomic bomb tests at the Southwest Pacific atoll of Bikini. Released to inactive duty as a Major in the U.S. Army Air Force in August 1947, he returned to the U.S. Department of Agriculture and the Bureau of Entomology and Plant Quarantine where he spent the remainder of his career, continuing to specialize in aircraft disinsection. [6]
Dichlorodiphenyltrichloroethane, commonly known as DDT, is a colorless, tasteless, and almost odorless crystalline chemical compound, an organochloride. Originally developed as an insecticide, it became infamous for its environmental impacts. DDT was first synthesized in 1874 by the Austrian chemist Othmar Zeidler. DDT's insecticidal action was discovered by the Swiss chemist Paul Hermann Müller in 1939. DDT was used in the second half of World War II to limit the spread of the insect-borne diseases malaria and typhus among civilians and troops. Müller was awarded the Nobel Prize in Physiology or Medicine in 1948 "for his discovery of the high efficiency of DDT as a contact poison against several arthropods". The WHO's anti-malaria campaign of the 1950s and 1960s relied heavily on DDT and the results were promising, though there was a resurgence in developing countries afterwards.
Insecticides are pesticides used to kill insects. They include ovicides and larvicides used against insect eggs and larvae, respectively. Insecticides are used in agriculture, medicine, industry and by consumers. Insecticides are claimed to be a major factor behind the increase in the 20th-century's agricultural productivity. Nearly all insecticides have the potential to significantly alter ecosystems; many are toxic to humans and/or animals; some become concentrated as they spread along the food chain.
Pyrethrum was a genus of several Old World plants now classified in either Chrysanthemum or Tanacetum which are cultivated as ornamentals for their showy flower heads. Pyrethrum continues to be used as a common name for plants formerly included in the genus Pyrethrum. Pyrethrum is also the name of a natural insecticide made from the dried flower heads of Chrysanthemum cinerariifolium and Chrysanthemum coccineum. The insecticidal compounds present in these species are pyrethrins.
Piperonyl butoxide (PBO) is a pale yellow to light brown liquid organic compound used as a synergist component of pesticide formulations. That is, despite having no pesticidal activity of its own, it enhances the potency of certain pesticides such as carbamates, pyrethrins, pyrethroids, and rotenone. It is a semisynthetic derivative of safrole.
The pyrethrins are a class of organic compounds normally derived from Chrysanthemum cinerariifolium that have potent insecticidal activity by targeting the nervous systems of insects. Pyrethrin naturally occurs in chrysanthemum flowers and is often considered an organic insecticide when it is not combined with piperonyl butoxide or other synthetic adjuvants. Their insecticidal and insect-repellent properties have been known and used for thousands of years.
Fly spray is a chemical insecticide that comes in an aerosol can that is sprayed into the air to kill flies. Fly sprays will kill various insects such as house flies and wasps.
Aerosol spray is a type of dispensing system which creates an aerosol mist of liquid particles. It comprises a can or bottle that contains a payload, and a propellant under pressure. When the container's valve is opened, the payload is forced out of a small opening and emerges as an aerosol or mist.
A pyrethroid is an organic compound similar to the natural pyrethrins, which are produced by the flowers of pyrethrums. Pyrethroids are used as commercial and household insecticides.
Permethrin is a medication and an insecticide. As a medication, it is used to treat scabies and lice. It is applied to the skin as a cream or lotion. As an insecticide, it can be sprayed onto outer clothing or mosquito nets to kill the insects that touch them.
An insect repellent is a substance applied to the skin, clothing, or other surfaces to discourage insects from landing or climbing on that surface. Insect repellents help prevent and control the outbreak of insect-borne diseases such as malaria, Lyme disease, dengue fever, bubonic plague, river blindness, and West Nile fever. Pest animals commonly serving as vectors for disease include insects such as flea, fly, and mosquito; and ticks (arachnids).
A mosquito net is a type of meshed curtain that is circumferentially draped over a bed or a sleeping area, to offer the sleeper barrier protection against bites and stings from mosquitos, flies, and other pest insects, and thus against the diseases they may carry. Examples of such preventable insect-borne diseases include malaria, dengue fever, yellow fever, zika virus, Chagas disease and various forms of encephalitis, including the West Nile virus.
Deltamethrin is a pyrethroid ester insecticide. Deltamethrin plays a key role in controlling malaria vectors, and is used in the manufacture of long-lasting insecticidal mosquito nets; however, resistance of mosquitos and bed bugs to deltamethrin has seen a widespread increase.
Bendiocarb is an acutely toxic carbamate insecticide used in public health and agriculture and is effective against a wide range of nuisance and disease vector insects. Many bendiocarb products are or were sold under the tradenames "Ficam" and "Turcam."
Indoor residual spraying or IRS is the process of spraying the inside of dwellings with an insecticide to kill mosquitoes that spread malaria. A dilute solution of insecticide is sprayed on the inside walls of certain types of dwellings—those with walls made from porous materials such as mud or wood but not plaster as in city dwellings. Mosquitoes are killed or repelled by the spray, preventing the transmission of the disease. In 2008, 44 countries employed IRS as a malaria control strategy. Several pesticides have historically been used for IRS, the first and most well-known being DDT.
A fogger is any device that creates a fog, typically containing an insecticide for killing insects and other arthropods. Foggers are often used by consumers as a low cost alternative to professional pest control services. The number of foggers needed for pest control depends on the size of the space to be treated, as stated for safety reasons on the instructions supplied with the devices. The fog may contain flammable gases, leading to a danger of explosion if a fogger is used in a building with a pilot light or other naked flame.
The history of malaria extends from its prehistoric origin as a zoonotic disease in the primates of Africa through to the 21st century. A widespread and potentially lethal human infectious disease, at its peak malaria infested every continent except Antarctica. Its prevention and treatment have been targeted in science and medicine for hundreds of years. Since the discovery of the Plasmodium parasites which cause it, research attention has focused on their biology as well as that of the mosquitoes which transmit the parasites.
RID is an Australian brand of personal insect repellent sold and distributed in Australia, New Zealand, and online.
Erik Andreas Rotheim was a Norwegian professional chemical engineer and inventor. He is best known for invention of the first aerosol spray can and valve that could hold and dispense fluids.
Agenor Mafra-Neto is a chemical ecology researcher and entrepreneur in the entomological field of insect chemical ecology. He is the CEO of ISCA Technologies, a company specializing in the development semiochemical solutions for pest management, robotic smart traps and nanosensors. Dr Mafra-Neto is the CEO and Director of Research and Development at ISCA Technologies, Inc. which he founded in 1996 in Riverside, California. ISCA Tecnologias, Ltda was founded in Brazil in 1997.
Lyle D. Goodhue was an internationally known inventor, research chemist and entomologist, with 105 U. S. and 25 foreign patents. He invented the "aerosol bomb", which was credited with saving the lives of many thousands of soldiers during World War II by dispensing malaria mosquito-killing liquid insecticides as a mist from small containers. The Bug Bomb became especially important to the war effort after the Philippines fell in 1942, when it was reported that malaria had played a major part in the defeat of American and British forces. After the war, this invention gave birth to a new international billion-dollar aerosol industry. A broad variety of consumer products ranging from cleaners and paints to hair spray and food have since been packaged in aerosol containers. Goodhue's other patents involved insect, bird and animal repellents; herbicides; nematocides; insecticides and other pesticides.