Adventist Health Studies

Last updated

Adventist Health Studies (AHS) is a series of long-term medical research projects of Loma Linda University with the intent to measure the link between lifestyle, diet, disease and mortality of Seventh-day Adventists.

Contents

Seventh-day Adventists have a lower risk than other Americans of certain diseases, and many researchers hypothesize that this is due to dietary and other lifestyle habits. This provides a special opportunity to answer scientific questions about how diet and other health habits affect the risk of suffering from many chronic diseases. [1]

Two studies on Adventist health involving 24,000 and 34,000 Californian Adventists were conducted over the last 40 years. Although not sponsored by the Adventist church itself, the church is supportive of the studies. These studies have been the subject of significant national media coverage on programs such as ABC News: World News Tonight , Good Morning America and in the National Geographic feature article "Longevity: The Secrets of a Long Life". [2]

There is a third larger ongoing study that includes Adventists throughout the United States and Canada.

Studies

Adventist Mortality Study

The first major study of Adventists began in 1960, and has become known as the Adventist Mortality Study. Consisting of 22,940 California Adventists, it entailed an intensive 5-year follow-up and a more informal 25-year follow-up.

"...[The] Adventist Mortality Study (1960–1965) did indicate that Adventist men lived 6.2 years longer than non-Adventist men in the concurrent American Cancer Society Study and Adventist women had a 3.7-year advantage over their counterparts. These statistics were based on life table analyses." [3]

Specifically, comparing death rates of Adventist compared to other Californians: [4]

Adventist Health Study 1 (AHS-1)

An additional study (1974–1988) involved approximately 34,000 Californian Adventists over 25 years of age. Unlike the mortality study, the purpose was to find out which components of the Adventist lifestyle give protection against disease.

The data from the study have been studied for more than a decade and the findings are numerous – linking diet to cancer [5] and coronary heart disease. [6] [7]

Specifically: [4]

Adventist Health Air Pollution Study (ASHMOG)

This is a sub-study of AHS-1. It began in 1976 and is still being conducted. It includes 6,328 Adventists from California. The study was funded by the Environmental Protection Agency.

The study linked the effects of various indoor and outdoor pollutants with respiratory diseases and lung cancer.

Adventist Health Study 2 (AHS-2)

The current study which began in 2002 with a goal of 125,000 Adventists continues to explore the links between lifestyle, diet, and disease among the broader base of Seventh-day Adventists in America and Canada. As of May 2006 it had an enrollment of 96,741. [8]

Dr. Gary Fraser with a team of researchers from the School of Public Health at Loma Linda University is conducting the study, which is funded by the National Cancer Institute. In July 2011, the National Institutes of Health awarded AHS-2 a $5.5 million 5-year grant to continue the study. [9] [10]

While the study is ongoing, some findings have been reported:

Adventist Religion & Health Study (AHRS)

This sub-study of AHS-2 began in 2006 and is funded by the National Institute on Aging. It is also known as the Biopsychosocial Religion and Health Study (BRHS).

The study has exceeded its goal of 10,000 participants with 11,835 subjects as of 2008. [4]

See also

Related Research Articles

<span class="mw-page-title-main">Coronary artery disease</span> Reduction of blood flow to the heart

Coronary artery disease (CAD), also called coronary heart disease (CHD), ischemic heart disease (IHD), myocardial ischemia, or simply heart disease, involves the reduction of blood flow to the heart muscle due to build-up of atherosclerotic plaque in the arteries of the heart. It is the most common of the cardiovascular diseases. Types include stable angina, unstable angina, and myocardial infarction.

<span class="mw-page-title-main">Dairy product</span> Food product made from milk

Dairy products or milk products, also known as lacticinia, are food products made from milk. The most common dairy animals are cow, water buffalo, nanny goat, and ewe. Dairy products include common grocery store food around the world such as yogurt, cheese, milk and butter. A facility that produces dairy products is a dairy. Dairy products are consumed worldwide to varying degrees. Some people avoid some or all dairy products because of lactose intolerance, veganism, or other health reasons or beliefs.

<span class="mw-page-title-main">Fat</span> Esters of fatty acid or triglycerides

In nutrition, biology, and chemistry, fat usually means any ester of fatty acids, or a mixture of such compounds, most commonly those that occur in living beings or in food.

A saturated fat is a type of fat in which the fatty acid chains have all single bonds. A fat known as a glyceride is made of two kinds of smaller molecules: a short glycerol backbone and fatty acids that each contain a long linear or branched chain of carbon (C) atoms. Along the chain, some carbon atoms are linked by single bonds (-C-C-) and others are linked by double bonds (-C=C-). A double bond along the carbon chain can react with a pair of hydrogen atoms to change into a single -C-C- bond, with each H atom now bonded to one of the two C atoms. Glyceride fats without any carbon chain double bonds are called saturated because they are "saturated with" hydrogen atoms, having no double bonds available to react with more hydrogen.

<span class="mw-page-title-main">French paradox</span> Observation that amount heart diseases French people have is much less than is expected

The French paradox is an apparently paradoxical epidemiological observation that French people have a relatively low incidence of coronary heart disease (CHD), while having a diet relatively rich in saturated fats, in apparent contradiction to the widely held belief that the high consumption of such fats is a risk factor for CHD. The paradox is that if the thesis linking saturated fats to CHD is valid, the French ought to have a higher rate of CHD than comparable countries where the per capita consumption of such fats is lower.

Lifestyle diseases can be defined as diseases linked with one's lifestyle. These diseases are non-communicable diseases. They are caused by lack of physical activity, unhealthy eating, alcohol, substance use disorders and smoking tobacco, which can lead to heart disease, stroke, obesity, type II diabetes and lung cancer. The diseases that appear to increase in frequency as countries become more industrialized and people live longer include Alzheimer's disease, arthritis, atherosclerosis, asthma, cancer, chronic liver disease or cirrhosis, chronic obstructive pulmonary disease, colitis, irritable bowel syndrome, type 2 diabetes, heart disease, hypertension, metabolic syndrome, chronic kidney failure, osteoporosis, PCOD, stroke, depression, obesity and vascular dementia.

<span class="mw-page-title-main">Mediterranean diet</span> Diet inspired by the Mediterranean region

The Mediterranean diet is a diet inspired by the eating habits and traditional food typical of southern Spain, southern Italy, and Crete, and formulated in the early 1960s. It is distinct from Mediterranean cuisine, which covers the actual cuisines of the Mediterranean countries, and from the Atlantic diet of Northwestern Spain and Portugal. While inspired by a specific time and place, the "Mediterranean diet" was later refined based on the results of multiple scientific studies.

<span class="mw-page-title-main">Cardiovascular disease</span> Class of diseases that involve the heart or blood vessels

Cardiovascular disease (CVD) is any disease involving the heart or blood vessels. CVDs constitute a class of diseases that includes: coronary artery diseases, heart failure, hypertensive heart disease, rheumatic heart disease, cardiomyopathy, arrhythmia, congenital heart disease, valvular heart disease, carditis, aortic aneurysms, peripheral artery disease, thromboembolic disease, and venous thrombosis.

<span class="mw-page-title-main">Hypercholesterolemia</span> High levels of cholesterol in the blood

Hypercholesterolemia, also called high cholesterol, is the presence of high levels of cholesterol in the blood. It is a form of hyperlipidemia, hyperlipoproteinemia, and dyslipidemia.

<span class="mw-page-title-main">Plant-based diet</span> Diet consisting mostly or entirely of plant-based foods

A plant-based diet is a diet consisting mostly or entirely of plant-based foods. Plant-based diets encompass a wide range of dietary patterns that contain low amounts of animal products and high amounts of fiber-rich plant products such as vegetables, fruits, whole grains, legumes, nuts and seeds. They do not need to be vegan or vegetarian but are defined in terms of low frequency of animal food consumption.

<span class="mw-page-title-main">Diseases of affluence</span> Health conditions thought to be a result of increasing wealth in society

Diseases of affluence, previously called diseases of rich people, is a term sometimes given to selected diseases and other health conditions which are commonly thought to be a result of increasing wealth in a society. Also referred to as the "Western disease" paradigm, these diseases are in contrast to so-called "diseases of poverty", which largely result from and contribute to human impoverishment. These diseases of affluence have vastly increased in prevalence since the end of World War II.

<span class="mw-page-title-main">Healthy diet</span> Type of diet

A healthy diet is a diet that maintains or improves overall health. A healthy diet provides the body with essential nutrition: fluid, macronutrients such as protein, micronutrients such as vitamins, and adequate fibre and food energy.

<span class="mw-page-title-main">Red meat</span> Meat which is red when raw, with high myoglobin content

In gastronomy, red meat is commonly red when raw, in contrast to white meat, which is pale in color before cooking. In culinary terms, only flesh from mammals or fowl is classified as red or white. In nutritional science, red meat is defined as any meat that has more of the protein myoglobin than white meat. White meat is defined as non-dark meat from fish or chicken.

<span class="mw-page-title-main">Phytosterol</span> Class of steroids derived from plants

Phytosterols are phytosteroids, similar to cholesterol, that serve as structural components of biological membranes of plants. They encompass plant sterols and stanols. More than 250 sterols and related compounds have been identified. Free phytosterols extracted from oils are insoluble in water, relatively insoluble in oil, and soluble in alcohols.

<span class="mw-page-title-main">Whole grain</span> Cereal containing endosperm, germ, and bran

A whole grain is a grain of any cereal and pseudocereal that contains the endosperm, germ, and bran, in contrast to refined grains, which retain only the endosperm.

<i>The China Study</i> 2005 book by T. Colin Campbell and Thomas M. Campbell II

The China Study: The Most Comprehensive Study of Nutrition Ever Conducted and the Startling Implications for Diet, Weight Loss and Long-term Health is a book by T. Colin Campbell and his son, Thomas M. Campbell II. The book argues for health benefits of a whole food plant-based diet. It was first published in the United States in January 2005 and had sold over one million copies as of October 2013, making it one of America's best-selling books about nutrition.

The European Prospective Investigation into Cancer and Nutrition (EPIC) study is a Europe-wide prospective cohort study of the relationships between diet and cancer, as well as other chronic diseases, such as cardiovascular disease. With over half a million participants, it is the largest study of diet and disease to be undertaken.

<span class="mw-page-title-main">Non-communicable disease</span> Medical condition

A non-communicable disease (NCD) is a disease that is not transmissible directly from one person to another. NCDs include Parkinson's disease, autoimmune diseases, strokes, heart diseases, cancers, diabetes, chronic kidney disease, osteoarthritis, osteoporosis, Alzheimer's disease, cataracts, and others. NCDs may be chronic or acute. Most are non-infectious, although there are some non-communicable infectious diseases, such as parasitic diseases in which the parasite's life cycle does not include direct host-to-host transmission.

<span class="mw-page-title-main">Seven Countries Study</span>

The Seven Countries Study is an epidemiological longitudinal study directed by Ancel Keys at what is today the University of Minnesota Laboratory of Physiological Hygiene & Exercise Science (LPHES). Begun in 1956 with a yearly grant of US$200,000 from the U.S. Public Health Service, the study was first published in 1978 and then followed up on its subjects every five years thereafter.

<span class="mw-page-title-main">Frank Hu</span> Nutrition researcher

Frank B. Hu is a Chinese American nutrition and diabetes researcher. He is Chair of the Department of Nutrition and the Fredrick J. Stare Professor of Nutrition and Epidemiology at the Harvard T.H. Chan School of Public Health, and Professor of Medicine at the Harvard Medical School.

References

  1. "The Adventist Health Studies". Loma Linda University. Retrieved 2008-05-31.
  2. Buettner, Dan (November 2005). "Longevity: The Secrets of a Long Life". National Geographic Society. Archived from the original on 21 June 2008. Retrieved 2008-05-31.
  3. "The Adventist Health Study: related investigations and future plans". Loma Linda University. Retrieved 2008-05-31.
  4. 1 2 3 "Religion and Health Study Progress". Adventist Health Studies Report 2008. Vol. V. 2008. p. 5.
  5. "The Adventist Health Study: findings for cancer". Loma Linda University. Retrieved 2008-05-31.
  6. "The Adventist Health Study: findings for coronary heart disease". Loma Linda University. Retrieved 2008-05-31.
  7. "The Adventist Health Study: findings for nuts". Loma Linda University. Retrieved 2008-05-31.
  8. "The Adventist Health Studies". Loma Linda University. Retrieved 2008-05-31.
  9. "Adventist Health Study-2 awarded $5.5 million from National Institutes of Health". Highland Community News. 2011-08-05. Retrieved 2011-08-06.
  10. "Loma Linda University given $5.5 million for health study". The Press-Enterprise. 2011-08-06. Retrieved 2011-08-07.
  11. Tonstad, Serena; Butler, Terry; Yan, Ru; Fraser, Gary E. (2009-02-02). "Type of Vegetarian Diet, Body Weight, and Prevalence of Type 2 Diabetes". Diabetes Care. National Institutes of Health. 32 (5): 791–6. doi:10.2337/dc08-1886. PMC   2671114 . PMID   19351712.
  12. "Vegetarian Dietary Patterns Are Associated With a Lower Risk of Metabolic Syndrome". American Diabetes Association. 2011-02-02. Retrieved 2011-08-07.
  13. Orlich, Michael J.; Mashchak, Andrew D.; Jaceldo-Siegl, Karen; Utt, Jason T.; Knutsen, Synnove F.; Sveen, Lars E.; Fraser, Gary E. (2022-06-08). "Dairy foods, calcium intakes, and risk of incident prostate cancer in Adventist Health Study-2". The American Journal of Clinical Nutrition. 116 (2): 314–324. doi:10.1093/ajcn/nqac093. ISSN   1938-3207. PMC   9348981 . PMID   35672028.