List of Schedule II controlled substances (U.S.)

Last updated

This is the list of Schedule II controlled substances as defined by the United States Controlled Substances Act. [1] The following findings are required for substances to be placed in this schedule: [2]

Contents

  1. The drug or other substance has a high potential for abuse.
  2. The drug or other substance has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions.
  3. Abuse of the drug or other substances may lead to severe psychological or physical dependence.

The complete list of Schedule II substances is as follows. The Administrative Controlled Substances Code Number and Federal Register citation for each substance is included.

ACSCN ClassDrug
9050opiate Codeine [3]
9334opiate Dihydroetorphine [4]
9190opiate Ethylmorphine [3]
9059opiate Etorphine hydrochloride [5]
9640opiateGranulated opium [3]
9193opiate Hydrocodone [3]
9150opiate Hydromorphone [3]
9260opiate Metopon [3]
9300opiate Morphine [3]
9668opiateNoroxymorphone [6]
9610opiateOpium extracts [3]
9620opiateOpium fluid [3]
9330opiate Oripavine [7]
9143opiate Oxycodone [3]
9652opiate Oxymorphone [3]
9639opiatePowdered opium [3]
9600opiateRaw opium [3]
9333opiate Thebaine [3]
9630opiate Tincture of opium [3]
opiate Opium poppy and poppy straw [8] [note 1]
9040stimulant Coca, leaves and any salt, compound, derivative or preparation of coca leaves [8] [note 1]
9041stimulant Cocaine, and its salts, isomers, derivatives and salts of isomers and derivatives [8] [note 1]
9180stimulant Ecgonine, and its salts, isomers, derivatives and salts of isomers and derivatives [8] [note 1]
9670opiateConcentrate of poppy straw (the crude extract of poppy straw in either liquid, solid or powder form which contains the phenanthrene alkaloids of the opium poppy) [9]
9737opiate Alfentanil [10]
9010opiate Alphaprodine [8] [note 1]
9020opiate Anileridine [8] [note 1]
9800opiate Bezitramide [8] [note 1]
9273opiateBulk dextropropoxyphene (non-dosage forms) [11]
9743opiate Carfentanil [12]
9120opiate Dihydrocodeine [8] [note 1]
9170opiate Diphenoxylate [8] [note 1]
9801opiate Fentanyl [8] [note 1]
9226opiate Isomethadone [8] [note 1]
9648opiate Levo-alphacetylmethadol [13]
9210opiate Levomethorphan [8] [note 1]
9220opiate Levorphanol [8] [note 1]
9240opiate Metazocine [8] [note 1]
9250opiate Methadone [8] [note 1]
9254opiate Methadone intermediate [8] [note 1]
9802opiate Moramide intermediate [8] [note 1]
9245opiate Oliceridine [14]
9230opiate Pethidine (meperidine) [8] [note 1]
9232opiate Pethidine intermediate A [8] [note 1]
9233opiate Pethidine intermediate B [8] [note 1]
9234opiate Pethidine intermediate C [8] [note 1]
9715opiate Phenazocine [8] [note 1]
9730opiate Piminodine [8] [note 1]
9732opiate Racemethorphan [8] [note 1]
9733opiate Racemorphan [8] [note 1]
9739opiate Remifentanil [15]
9740opiate Sufentanil [16]
9780opiate Tapentadol [17]
9729opiate Thiafentanil [18]
1100stimulant Amphetamine, its salts, optical isomers, and salts of its optical isomers [19]
1105stimulant Methamphetamine, its salts, optical isomers, and salts of optical isomers [19]
1631stimulant Phenmetrazine and its salts [20]
1724stimulant Methylphenidate [20]
1205stimulant Lisdexamfetamine, its salts, isomers, and salts of its isomers [21]
2125depressant Amobarbital [22]
2550depressant Glutethimide [23]
2270depressant Pentobarbital [22]
7471depressant Phencyclidine [24]
2315depressant Secobarbital [22]
7379hallucinogen Nabilone [25]
7365hallucinogen Dronabinol oral solution [26]
8501precursor Phenylacetone [27]
7460precursor 1-phenylcyclohexylamine [27]
8603precursor1-piperidinocyclohexanecarbonitrile (PCC) [27]
8333precursor4-anilino-N-phenethyl-4-piperidine (4-ANPP) [28]
8366precursor Norfentanyl [29]

See Also

Notes

  1. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 This substance was expressly scheduled by the Controlled Substances Act on October 27, 1970. The 1974 Federal Register ruling (by Administrator John R. Bartels, Jr.) merely organized its listing in the Code of Federal Regulations.

Related Research Articles

<span class="mw-page-title-main">Controlled Substances Act</span> United States drug-regulating law

The Controlled Substances Act (CSA) is the statute establishing federal U.S. drug policy under which the manufacture, importation, possession, use, and distribution of certain substances is regulated. It was passed by the 91st United States Congress as Title II of the Comprehensive Drug Abuse Prevention and Control Act of 1970 and signed into law by President Richard Nixon. The Act also served as the national implementing legislation for the Single Convention on Narcotic Drugs.

<span class="mw-page-title-main">Propylhexedrine</span> Topical nasal decongestant

Propylhexedrine, commonly sold under the brand name Benzedrex, is an alkylamine primarily utilized as a topical nasal decongestant. Its main indications are relief of congestion due to colds, allergies, and allergic rhinitis.

<span class="mw-page-title-main">HU-210</span> Synthetic cannabinoid

HU-210 is a synthetic cannabinoid that was first synthesized in 1988 from (1R,5S)-myrtenol by a group led by Raphael Mechoulam at the Hebrew University. HU-210 is 100 to 800 times more potent than natural THC from cannabis and has an extended duration of action. HU-210 has a binding affinity of 0.061 nM at CB1 and 0.52 nM at CB2 in cloned human cannabinoid receptors compared to delta-9-THC of 40.7 nM at CB1. HU-210 is the (–)-1,1-dimethylheptyl analog of 11-hydroxy- Δ8- tetrahydrocannabinol; in some references it is called 1,1-dimethylheptyl- 11-hydroxytetrahydrocannabinol. The abbreviation "HU" stands for Hebrew University.

<span class="mw-page-title-main">Removal of cannabis from Schedule I of the Controlled Substances Act</span> Proposed changes to the legal status of cannabis in U.S. federal law

In the United States, the removal of cannabis from Schedule I of the Controlled Substances Act is a proposed legal and administrative change in cannabis-related law at the federal level. It has been proposed repeatedly since 1972. The category is the most tightly restricted category reserved for drugs that have "no currently accepted medical use."

<span class="mw-page-title-main">Tiletamine</span> Chemical compound

Tiletamine is a dissociative anesthetic and pharmacologically classified as an NMDA receptor antagonist. It is related chemically to ketamine. Tiletamine hydrochloride exists as odorless white crystals.

<span class="mw-page-title-main">Zolazepam</span> Chemical compound

Zolazepam (Flupyrazapon) is a pyrazolodiazepinone derivative structurally related to the benzodiazepine drugs, which is used as an anaesthetic for a wide range of animals in veterinary medicine. Zolazepam is usually administered in combination with other drugs such as the NMDA antagonist tiletamine or the α2 adrenergic receptor agonist xylazine, depending on what purpose it is being used for. It is around four times the potency of diazepam but it is both water-soluble and un-ionized at physiological pH meaning that its onset is very fast.

<span class="mw-page-title-main">Meprodine</span> Chemical compound

Meprodine is an opioid analgesic that is an analogue of pethidine (meperidine). It is closely related to the drug prodine, the only difference being that meprodine has an ethyl group rather than a methyl at the 3-position of the piperidine ring.

<span class="mw-page-title-main">Eutylone</span> Designer drug of the cathinone class

Eutylone is a stimulant and empathogenic compound developed in the 1960s, which is classified as a designer drug. It was first reported to the EMCDDA in 2014 and became widespread internationally in 2019-2020 following bans on the related compound ephylone. It is not a natural, but a synthetic cathinone. In 2021, eutylone was the most common cathinone identified by the Drug Enforcement Administration in the United States.

<span class="mw-page-title-main">THJ-2201</span> Synthetic cannabinoid

THJ-2201 is an indazole-based synthetic cannabinoid that presumably acts as a potent agonist of the CB1 receptor and has been sold online as a designer drug.

<i>alpha</i>-Pyrrolidinohexiophenone Stimulant drug

α-Pyrrolidinohexiophenone is a synthetic stimulant drug of the cathinone class developed in the 1960s which has been reported as a novel designer drug.

<span class="mw-page-title-main">4-Methylphenethylacetylfentanyl</span> Chemical compound

4-Methylphenethylacetylfentanyl is an opioid analgesic that is an analog of fentanyl and has been sold as a designer drug.

<span class="mw-page-title-main">5F-MDMB-PICA</span> Chemical compound

5F-MDMB-PICA (MDMB-5F-PICA) is a designer drug and synthetic cannabinoid. In 2018, it was the fifth-most common synthetic cannabinoid identified in drugs seized by the Drug Enforcement Administration.

<span class="mw-page-title-main">5F-EDMB-PINACA</span> Chemical compound

5F-EDMB-PINACA is a designer drug and synthetic cannabinoid. In 2018, it was the fourth-most common synthetic cannabinoid identified in drugs seized by the Drug Enforcement Administration.

<span class="mw-page-title-main">4F-MDMB-BINACA</span> Chemical compound

4F-MDMB-BINACA (also known as MDMB-4F-BINACA, 4F-MDMB-BUTINACA or 4F-ADB) is an indazole-based synthetic cannabinoid from the indazole-3-carboxamide family. It has been used as an active ingredient in synthetic cannabis products and sold as a designer drug since late 2018. 4F-MDMB-BINACA is an agonist of the CB1 receptor (EC50 = 7.39 nM), though it is unclear whether it is selective for this target. In December 2019, the UNODC announced scheduling recommendations placing 4F-MDMB-BINACA into Schedule II throughout the world.

<span class="mw-page-title-main">Serdexmethylphenidate</span> CNS Stimulant (prodrug)

Serdexmethylphenidate is a prodrug of dexmethylphenidate created by the pharmaceutical company KemPharm. The compound was first approved by the FDA as one of the active ingredients in Azstarys for the treatment of attention deficit hyperactivity disorder (ADHD) in children, adolescents, and adults in March 2021. Serdexmethylphenidate is a prodrug which has a delayed onset of action and a prolonged duration of effects compared to dexmethylphenidate, its parent compound.

<span class="mw-page-title-main">Thenylfentanyl</span> A fentanyl analogue

Thenylfentanyl is an analogue of fentanyl where the phenethylamine side-chain has been replaced by a thiophenylmethyl group. It was temporarily scheduled by the Drug Enforcement Administration in 1985, due to fears it would be used as a designer drug. But in 2010 the DEA acknowledged it was essentially inactive. Subsequently, the substance was since deregulated.

References

  1. ↑ "21 C.F.R. 1308.12 (Schedule II)". Code of Federal Regulations . Retrieved September 7, 2023.
  2. ↑ 21 U.S.C.   § 812(b)(4) retrieved October 7, 2007
  3. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 Ingersoll, John (September 29, 1971). "Schedules of Controlled Substances: Removal of Naloxone From Control" (PDF). Isomer Design. Bureau of Narcotics and Dangerous Drugs. Archived from the original (PDF) on September 16, 2021. Retrieved September 7, 2023.
  4. ↑ Mercado, Julio (November 17, 2000). "Schedule II Control of Dihydroetorphine Under the Controlled Substances Act". Federal Register . Drug Enforcement Administration . Retrieved September 7, 2023.
  5. ↑ Bartels, Jr., John R. (March 29, 1974). "Etorphine Hydrochloride Transfer to Schedule II" (PDF). Isomer Design. Drug Enforcement Administration. Archived from the original (PDF) on September 26, 2021. Retrieved September 7, 2023.
  6. ↑ Dhillon, Uttam (August 16, 2019). "Listing of Noroxymorphone in the Code of Federal Regulations and Assignment of a Controlled Substances Code Number". Federal Register . Drug Enforcement Administration . Retrieved September 7, 2023.
  7. ↑ Leonhart, Michele (September 24, 2007). "Designation of Oripavine as a Basic Class of Controlled Substance". Federal Register . Drug Enforcement Administration . Retrieved September 7, 2023.
  8. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Bartels Jr., John R. (June 20, 1974). "PART 1308— SCHEDULES OF CONTROLLED SUBSTANCES: Annual Publication" (PDF). Government Publishing Office . Drug Enforcement Administration. Archived from the original (PDF) on September 6, 2023. Retrieved September 6, 2023.
  9. ↑ Bartels, Jr., John R. (February 14, 1975). "Concentrate of Poppy Straw, Addition to Schedule II and Authorizing its Importation" (PDF). Isomer Design. Drug Enforcement Administration. Archived from the original (PDF) on September 26, 2021. Retrieved September 7, 2023.
  10. ↑ Lawn, John (January 23, 1987). "Rescheduling of Alfentanil from Schedule I to Schedule II" (PDF). Isomer Design. Drug Enforcement Administration. Archived from the original (PDF) on July 28, 2019. Retrieved September 7, 2023.
  11. ↑ Bensinger, Peter (July 22, 1980). "Control of Bulk Dextropropoxyphene (Non-dosage Forms) in Schedule II as an Opiate" (PDF). Isomer Design. Drug Enforcement Administration. Archived from the original (PDF) on March 24, 2016. Retrieved September 7, 2023.
  12. ↑ Lawn, John (October 28, 1988). "Placement of Carfentanil into Schedule II" (PDF). Isomer Design. Drug Enforcement Administration. Archived from the original (PDF) on March 22, 2016. Retrieved September 7, 2023.
  13. ↑ Bonner, Robert (August 18, 1993). "Schedules of Controlled Substances; Transfer of Levo-acetylmethadol from Schedule I into Schedule II" (PDF). Isomer Design. Drug Enforcement Administration. Archived from the original (PDF) on July 28, 2019. Retrieved January 16, 2023.
  14. ↑ Evans, D. Christopher (July 12, 2021). "Schedules of Controlled Substances: Placement of Oliceridine in Schedule II". Federal Register . Drug Enforcement Administration . Retrieved September 7, 2023.
  15. ↑ Milford, Jr., James S. (November 5, 1996). "Schedules of Controlled Substances: Placement of Remifentanil Into Schedule II". Federal Register . Drug Enforcement Administration . Retrieved January 16, 2023.
  16. ↑ Mullen, Jr., Francis M. (May 25, 1984). "Schedules of Controlled Substances; Rescheduling of Sufentanil into Schedule II" (PDF). Isomer Design. Drug Enforcement Administration. Archived (PDF) from the original on May 19, 2019. Retrieved January 16, 2023.
  17. ↑ Leonhart, Michele (May 21, 2009). "Schedules of Controlled Substances: Placement of Tapentadol Into Schedule II". Federal Register . Drug Enforcement Administration . Retrieved January 16, 2023.
  18. ↑ Dhillon, Uttam (June 10, 2019). "Schedules of Controlled Substances: Placement of Thiafentanil in Schedule II". Federal Register . Drug Enforcement Administration . Retrieved September 7, 2023.
  19. 1 2 Ingersoll, John (July 7, 1971). "Amphetamine, Methamphetamine, and Optical Isomers" (PDF). Isomer Design. Bureau of Narcotics and Dangerous Drugs. Archived (PDF) from the original on March 3, 2022. Retrieved January 16, 2023.
  20. 1 2 Finlator, John (October 28, 1971). "Phenmetrazine and its salts, and Methylphenidate" (PDF). Isomer Design. Bureau of Narcotics and Dangerous Drugs. Archived (PDF) from the original on March 3, 2022. Retrieved January 16, 2023.
  21. ↑ Leonhart, Michele (May 3, 2007). "Schedules of Controlled Substances: Placement of Lisdexamfetamine Into Schedule II". Federal Register . Drug Enforcement Administration. Archived from the original on January 16, 2023. Retrieved January 16, 2023.
  22. 1 2 3 Bartels, Jr., John R. (November 13, 1973). "Schedule II Control of Amobarbital, Pentobarbital, Secobarbital, and their salts" (PDF). Isomer Design. Drug Enforcement Administration. Archived (PDF) from the original on March 3, 2022. Retrieved January 16, 2023.
  23. ↑ Bonner, Robert (March 21, 1991). "Schedules of Controlled Substances: Transfer of Glutethimide from Schedule III to Schedule II" (PDF). Isomer Design. Drug Enforcement Administration. Archived (PDF) from the original on March 3, 2022. Retrieved January 16, 2023.
  24. ↑ Bensinger, Peter (January 25, 1978). "Placement of Phencyclidine in Schedule II" (PDF). Isomer Design. Drug Enforcement Administration. Archived (PDF) from the original on March 3, 2022. Retrieved January 16, 2023.
  25. ↑ Lawn, John (April 7, 1987). "Placement of Nabilone in Schedule II" (PDF). Government Publishing Office . Drug Enforcement Administration. p. 11042. Archived from the original (PDF) on April 30, 2023. Retrieved September 7, 2023.
  26. ↑ Patterson, Robert (November 22, 2017). "Schedules of Controlled Substances: Placement of FDA-Approved Products of Oral Solutions Containing Dronabinol [(-)-delta-9-trans-tetrahydrocannabinol (delta-9-THC)] in Schedule II". Federal Register . Drug Enforcement Administration . Retrieved September 7, 2023.
  27. 1 2 3 Bensinger, Peter (February 11, 1980). "Schedules of Controlled Substances; Schedule II Placement of Phenylacetone; (Phenyl-2-propanone, P2P, methyl benzyl ketone, benzyl methyl ketone)" (PDF). Isomer Design. Drug Enforcement Administration. Archived (PDF) from the original on March 3, 2022. Retrieved January 16, 2023.
  28. ↑ Leonhart, Michele (June 29, 2010). "Control of Immediate Precursor Used in the Illicit Manufacture of Fentanyl as a Schedule II Controlled Substance". Federal Register. Drug Enforcement Administration. Archived from the original on January 16, 2023. Retrieved January 16, 2023.
  29. ↑ Dhillon, Uttam (April 17, 2020). "Control of the Immediate Precursor Norfentanyl Used in the Illicit Manufacture of Fentanyl as a Schedule II Controlled Substance". Federal Register . Drug Enforcement Administration . Retrieved September 7, 2023.
This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.