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Globo H (globohexaosylceramide) is a globo-series glycosphingolipid antigen that is present on the outer membrane of some cancer cells. Globo H is not expressed in normal tissue cells, but is expressed in a number of types of cancers, including cancers of the breast, prostate, and pancreas. Globo H's exclusivity for cancer cells makes it a target of interest for cancer therapies.
References
- ↑ "Avelino Corma Canós, Mark E. Davis and Galen D. Stucky, Prince of Asturias Award for Technical and Scientific Research - Communication".
- ↑ "Mark E. Davis". Caltech. Archived from the original on 14 April 2019. Retrieved 7 April 2013.
- ↑ Arhancet, Juan P.; Davis, Mark E.; Merola, Joseph S.; Hanson, Brian E. (8 June 1989). "Hydroformylation by supported aqueous-phase catalysis: a new class of heterogeneous catalysts". Nature. 339 (6224): 454–455. Bibcode:1989Natur.339..454A. doi:10.1038/339454a0. S2CID 34932513.
- ↑ Davis, Mark E.; Saldarriaga, Carlos; Montes, Consuelo; Garces, Juan; Crowdert, Cyrus (25 February 1988). "A molecular sieve with eighteen-membered rings". Nature. 331 (6158): 698–699. Bibcode:1988Natur.331..698D. doi:10.1038/331698a0. S2CID 26623258.
- 1 2 3 Ahmed, F (Dec 26, 2007). "Profile of Mark E. Davis". Proceedings of the National Academy of Sciences of the United States of America. 104 (52): 20651–3. Bibcode:2007PNAS..10420651A. doi: 10.1073/pnas.0704959105 . PMC 2409208 . PMID 18093958.
- ↑ Schluep, T. (1 March 2006). "Preclinical Efficacy of the Camptothecin-Polymer Conjugate IT-101 in Multiple Cancer Models". Clinical Cancer Research. 12 (5): 1606–1614. doi: 10.1158/1078-0432.CCR-05-1566 . PMID 16533788.
- 1 2 Gellene, Denise (11 August 2007). "Science begins at home". LA Times. Retrieved 7 April 2013.
- ↑ "Professor Mark E Davis".
- ↑ Fesenmaier, Kimm (28 July 2011). "Caltech Professor Runs to Victories on the World Stage". Caltech News. Retrieved 7 April 2013.
