U.S. Route 412 is an east–west United States highway, first commissioned in 1982. U.S. 412 overlaps expressway-grade Cimarron Turnpike from Tulsa west to Interstate 35 and the Cherokee Turnpike from 5 miles (8.0 km) east of Chouteau, Oklahoma, to 8 miles (13 km) west of the Arkansas state line. It runs the entire length of the Oklahoma Panhandle and traverses the Missouri Bootheel.
U.S. Route 69 (US 69) is a major north–south United States highway. When it was first created, it was only 150 miles (241 km) long, but it has since been expanded into a Minnesota to Texas cross-country route. The highway's southern terminus is in Port Arthur, Texas at an intersection with State Highway 87. Its northern terminus is in Albert Lea, Minnesota at Minnesota State Highway 13.
U.S. Route 160 (US 160) is a 1,465-mile-long (2,358 km) east–west United States Numbered Highway in the Midwestern and Western United States. The western terminus of the route is at US 89 five miles (8.0 km) west of Tuba City, Arizona. The eastern terminus is at US 67 and Missouri 158 southwest of Poplar Bluff, Missouri. Its route, if not its number, was made famous in song in 1975, as the road from Wolf Creek Pass to Pagosa Springs, Colorado in C.W. McCall's country music song "Wolf Creek Pass".
Route 14 is a state highway traveling through the southern part of the U.S. state of Missouri. Its western terminus is at U.S. Route 60 (US 60) in Marionville, and its eastern terminus is at US 63 on the northern edge of West Plains. Route 14 is a two-lane highway for its entire length, however, there are plans to widen Route 14 in some spots.
Route 13 is a highway in Missouri which runs almost the entire north–south length of the state. Its northern terminus is at U.S. Route 69/136 in Bethany. Its southern terminus is at the Arkansas state line in downtown Blue Eye, Missouri–Arkansas where it continues as Highway 21. It is one of the original state highways of Missouri.
Route 413 is a highway in Missouri running between Route 13 in Springfield and Route 13 in Reeds Spring. It is an older alignment of Route 13 which was later rerouted. Except for two sections, the road runs concurrent with other designations for its entire length.
Route 76 is a highway in the west half of southern Missouri running between U.S. Route 60 and U.S. Route 63 at Willow Springs and the Oklahoma state line near Tiff City where it continues as a county road. It bypasses Branson on the Ozark Mountain High Road and is the namesake of the Branson strip, 76 Country Blvd. The road runs for its entirety through the Missouri Ozarks, and is at times very hilly and curvy.
Route 7 is a state highway with its northern terminus at U.S. Route 24 in northeast Independence and its southern terminus at Interstate 44 southeast of Richland. The section between Harrisonville and Clinton provides an important link for traffic between Springfield and Kansas City.
Route 265 is a highway in southwestern Missouri. Its northern terminus is at Interstate 44 in Mount Vernon; its southern terminus is at U.S. Route 65 south of Branson. Much of the highway is concurrent with other routes. It is also known as the Ozark Mountain Parkway.
Route 39 is a two-lane highway in southwestern Missouri. Its northern terminus is at U.S. Route 54 between Collins and El Dorado Springs at the community of Cedar Springs; its southern terminus is at the Arkansas state line where it continues as Highway 221.
Route 37 is a highway in southwest Missouri. Its northern terminus is at U.S. Route 160 in Golden City ; its southern terminus is at the Arkansas state line where it continues as Highway 37, though it only runs very briefly before ending at U.S. Route 62 in Gateway, Arkansas.
Route 245 is a short two-lane highway in southwest Missouri. Its northern terminus is at Route 32 about three miles (5 km) west of Fair Play; its southern terminus is at U.S. Route 160 about seven miles (11 km) east of Greenfield.
Route 248 is a highway in southwestern Missouri. Its eastern terminus is at U.S. Route 65 in Branson. Its western terminus is at Route 76/Route 86/Route 112 in Cassville.
Route 173 is a highway in southwestern Missouri. Its northern terminus is at Route 265/Route 413 in Elsey; its southern terminus is at Route 76 in Cape Fair.
Route 165 and County Road 165 (CR 165) form a loop around the west side of Branson, Missouri, in Taney and Stone counties. The highway's southern terminus is at U.S. Route 65 (US 65) south of Branson, in Hollister. Even though the county road designation belongs to Taney County, it briefly enters Stone County at Table Rock State Park. Upon re-entering Taney County, it crosses the Table Rock Lake Dam, along with Route 265, at Table Rock Lake. Its northern terminus is at US 65 along the Red Route in north Branson.
Route 123 is a highway in southwestern Missouri. Its northern terminus is at U.S. Route 54 in Weaubleau; its southern terminus is at U.S. Route 160 in Willard.
Route 88 was a 6.8-mile-long (10.9 km) state highway located entirely within the city limits of Springfield. Its western terminus was at Sunshine Street. Its eastern terminus was at Glenstone Avenue. It was a collection of older highways which were still under state maintenance.
U.S. Route 65 is a north–south U.S. highway that runs from Clayton, Louisiana to Albert Lea, Minnesota. In Missouri, the highway enters the state from Arkansas, just south of Branson. The highway exits the state into Iowa near South Lineville.
A total of eight special routes of U.S. Route 65 exist, divided between the U.S. states of Arkansas and Missouri. Currently, they are all business loops, although a spur route in Pine Bluff, Arkansas and bypass routes in Baton Rouge, Louisiana and Springfield, Missouri both existed in the past.
North Carolina Highway 65 (NC 65) is a primary state highway in the U.S. state of North Carolina. Traveling east–west within the Piedmont Triad, it connects the towns of Rural Hall, Walnut Cove, Stokesdale and Wentworth with the city of Reidsville.
Route 248 / Route 265 / Route 413 in Galena 
US 160 north of Forsyth 
