Pulse sequence

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Timing diagram for an MRI spin echo pulse sequence. MRI 2DFT SE PulseSequence.png
Timing diagram for an MRI spin echo pulse sequence.
Graphical representation of a pulse sequence for a homonuclear NOESY experiment. The three bars represent three 90deg pulses. Noesy pulse sequence.png
Graphical representation of a pulse sequence for a homonuclear NOESY experiment. The three bars represent three 90° pulses.
An INEPT NMR pulse sequence for a heteronuclear experiment. The thin bar denotes a 90deg pulse, while the thick bar denotes a 180deg pulse. INEPT is a common building block of NMR experiments to improve N signal. INEPT Pulse Sequence.png
An INEPT NMR pulse sequence for a heteronuclear experiment. The thin bar denotes a 90° pulse, while the thick bar denotes a 180° pulse. INEPT is a common building block of NMR experiments to improve N signal.

In Fourier transform NMR spectroscopy and imaging, a pulse sequence describes a series of radio frequency pulses applied to the sample, such that the free induction decay is related to the characteristic frequencies of the desired signals. After applying a Fourier transform, the signal can be represented in the frequency domain as the NMR spectrum. In magnetic resonance imaging, additional gradient pulses are applied by switching magnetic fields that exhibit a space-dependent gradient which can be used to reconstruct spatially resolved images after applying Fourier transforms. [2]

Contents

The outcome of pulse sequences is often analyzed using the product operator formalism.

See also

Related Research Articles

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<span class="mw-page-title-main">Free induction decay</span>

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<span class="mw-page-title-main">Pulsed electron paramagnetic resonance</span>

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<span class="mw-page-title-main">MRI sequence</span>

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Hyperpolarized 129Xe gas magnetic resonance imaging (MRI) is a medical imaging technique used to visualize the anatomy and physiology of body regions that are difficult to image with standard proton MRI. In particular, the lung, which lacks substantial density of protons, is particularly useful to be visualized with 129Xe gas MRI. This technique has promise as an early-detection technology for chronic lung diseases and imaging technique for processes and structures reliant on dissolved gases. 129Xe is a stable, naturally occurring isotope of xenon with 26.44% isotope abundance. It is one of two Xe isotopes, along with 131Xe, that has non-zero spin, which allows for magnetic resonance. 129Xe is used for MRI because its large electron cloud permits hyperpolarization and a wide range of chemical shifts. The hyperpolarization creates a large signal intensity, and the wide range of chemical shifts allows for identifying when the 129Xe associates with molecules like hemoglobin. 129Xe is preferred over 131Xe for MRI because 129Xe has spin 1/2, a longer T1, and 3.4 times larger gyromagnetic ratio (11.78 MHz/T).

References

  1. M H Levitt (2008). Spin Dynamics. John Wiley & Sons Ltd. ISBN   978-0470511176.
  2. Bernstein, M.A.; King, K.E.; Zhou, X.J.; Fong, W. (2004). Handbook of MRI Pulse Sequences . Retrieved 2008-04-08.