Phototoxic tar dermatitis

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Phototoxic tar dermatitis results from coal tar, creosote, crude coal tar, or pitch, in conjunction with sunlight exposure, which induces a sunburn reaction associated with severe burning sensation. [1] :32

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Coal tar is a thick dark liquid which is a by-product of the production of coke and coal gas from coal. It has both medical and industrial uses. Medicinally it is a topical medication applied to skin to treat psoriasis and seborrheic dermatitis (dandruff). It may be used in combination with ultraviolet light therapy. Industrially it is a railway tie preservative and used in the surfacing of roads.

Creosote

Creosote is a category of carbonaceous chemicals formed by the distillation of various tars and pyrolysis of plant-derived material, such as wood or fossil fuel. They are typically used as preservatives or antiseptics.

Coke (fuel) A grey, hard and porous fuel with high carbon content and few impurities.

Coke is a grey, hard, and porous fuel with a high carbon content and few impurities, made by heating coal or oil in the absence of air—a destructive distillation process. It is an important industrial product, used mainly in iron ore smelting, but also as a fuel in stoves and forges when air pollution is a concern.

Naphthalene

Naphthalene is an organic compound with formula C
10
H
8
. It is the simplest polycyclic aromatic hydrocarbon, and is a white crystalline solid with a characteristic odor that is detectable at concentrations as low as 0.08 ppm by mass. As an aromatic hydrocarbon, naphthalene's structure consists of a fused pair of benzene rings. It is best known as the main ingredient of traditional mothballs.

Cresols are organic compounds which are methylphenols. They are a widely occurring natural and manufactured group of aromatic organic compounds, which are categorized as phenols. Depending on the temperature, cresols can be solid or liquid because they have melting points not far from room temperature. Like other types of phenols, they are slowly oxidized by long exposure to air, and the impurities often give samples of cresols a yellowish to brownish red tint. Cresols have an odor characteristic to that of other simple phenols, reminiscent to some of a "coal tar" smell. The name cresol reflects their structure, being phenols, and their traditional source, creosote.

Coal gas is a flammable gaseous fuel made from coal and supplied to the user via a piped distribution system. It is produced when coal is heated strongly in the absence of air. Town gas is a more general term referring to manufactured gaseous fuels produced for sale to consumers and municipalities.

Dandruff A skin condition mainly affecting the scalp causing flaking and itchiness

Dandruff is a skin condition that mainly affects the scalp. Symptoms include flaking and sometimes mild itchiness. It can result in social or self-esteem problems. A more severe form of the condition, which includes inflammation of the skin, is known as seborrhoeic dermatitis.

Seborrhoeic dermatitis

Seborrhoeic dermatitis, also known as seborrhoea, is a long-term skin disorder. Symptoms include red, scaly, greasy, itchy, and inflamed skin. Areas of the skin rich in oil-producing glands are often affected including the scalp, face, and chest. It can result in social or self-esteem problems. In babies, when the scalp is primarily involved, it is called cradle cap. Dandruff is a milder form of the condition without inflammation.

Dry distillation

Dry distillation is the heating of solid materials to produce gaseous products. The method may involve pyrolysis or thermolysis, or it may not. If there are no chemical changes, just phase changes, it resembles classical distillation, although it will generally need higher temperatures. Dry distillation in which chemical changes occur is a type of destructive distillation or cracking.

Photodermatitis Form of allergic contact dermatitis in which the allergen must be activated by light to sensitize the allergic response

Photodermatitis, sometimes referred to as sun poisoning or photoallergy, is a form of allergic contact dermatitis in which the allergen must be activated by light to sensitize the allergic response, and to cause a rash or other systemic effects on subsequent exposure. The second and subsequent exposures produce photoallergic skin conditions which are often eczematous. It is distinct from sunburn.

Tar paper

Tar paper is a heavy-duty paper used in construction. Tar paper is made by impregnating paper or fiberglass mat with tar, producing a waterproof material useful for roof construction. Tar paper is distinguished from roofing felt which is impregnated with asphalt instead of tar; but these two products are used the same way, and their names sometimes are used informally as synonyms.

Pine tar

Pine tar is a sticky material produced by the high temperature carbonization of pine wood in anoxic conditions. The wood is rapidly decomposed by applying heat and pressure in a closed container; the primary resulting products are charcoal and pine tar.

Coal gasification is the process of producing syngas—a mixture consisting primarily of carbon monoxide (CO), hydrogen (H2), carbon dioxide (CO2), natural gas (CH4), and water vapour (H2O)—from coal and water, air and/or oxygen.

Destructive distillation

Destructive distillation is a chemical process in which decomposition of unprocessed material is achieved by heating it to a high temperature; the term generally applies to processing of organic material in the absence of air or in the presence of limited amounts of oxygen or other reagents, catalysts, or solvents, such as steam or phenols. It is an application of pyrolysis. The process breaks up or 'cracks' large molecules. Coke, coal gas, gas carbon, coal tar, ammonia liquor, and coal oil are examples of commercial products historically produced by the destructive distillation of coal.

Tar Dark viscous organic liquid

Tar is a dark brown or black viscous liquid of hydrocarbons and free carbon, obtained from a wide variety of carbon based matter through destructive distillation. Tar can be produced from coal, wood, petroleum, or peat.

Black tar heroin Impure form of heroin

Black tar heroin is a free base form of heroin that is sticky like tar or hard like coal. Its dark color is the result of crude processing methods that leave behind impurities. Despite its name, black tar heroin can also be dark orange or dark brown in appearance. It is generally less expensive than other forms of heroin.

Wrights Coal Tar Soap

Created by William Valentine Wright in 1860, Wright's Coal Tar Soap was a popular brand of antiseptic soap designed to thoroughly cleanse the skin. It was an orange colour.

Sealcoat

Sealcoating, or pavement sealing, is the process of applying a protective coating to asphalt-based pavements to provide a layer of protection from the elements: water, oils, and U.V. damage.

Goeckerman therapy is a regimen for treatment of moderate to severe plaque psoriasis using a combination of crude coal tar and artificial ultraviolet radiation. It is a specialized form of light therapy.

Benzo(<i>c</i>)fluorene Chemical compound

Benzo[c]fluorene is a polycyclic aromatic hydrocarbon (PAH) with mutagenic activity. It is a component of coal tar, cigarette smoke and smog and thought to be a major contributor to its carcinogenic properties. The mutagenicity of benzo[c]fluorene is mainly attributed to formation of metabolites that are reactive and capable of forming DNA adducts. According to the KEGG it is a group 3 carcinogen. Other names for benzo[c]fluorene are 7H-benzo[c]fluorene, 3,4-benzofluorene, and NSC 89264.

References

  1. James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN   978-0-7216-2921-6.