The 1881 St Ives by-election was fought on 11 April 1881. The by-election was fought due to the death of the incumbent Liberal MP, Sir Charles Reed. [1] The seat was gained by the Conservatives.
| Party | Candidate | Votes | % | ±% | |
|---|---|---|---|---|---|
| Conservative | Charles Campbell Ross | 462 | 56.2 | +8.8 | |
| Liberal | William Cole Pendarves | 360 | 43.8 | −8.8 | |
| Majority | 102 | 12.4 | N/A | ||
| Turnout | 822 | 81.2 | −0.4 | ||
| Registered electors | 1,012 | ||||
| Conservative gain from Liberal | Swing | +8.8 | |||
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