| Singles | |
|---|---|
| 1988 Virginia Slims of Indianapolis | |
| 1987 Champion |  Halle Cioffi |
| Champion |  Katerina Maleeva |
| Runner-up | Zina Garrison |
| Final score | 6–3, 2–6, 6–2 |
Halle Cioffi was the defending champion but lost in the second round to Gretchen Magers.
Katerina Maleeva won in the final 6–3, 2–6, 6–2 against Zina Garrison.
A champion seed is indicated in bold text while text in italics indicates the round in which that seed was eliminated.
Zina Garrison (final) Katerina Maleeva (champion) Stephanie Rehe (semifinals)
Larisa Savchenko (second round)
Helen Kelesi (first round)
Anne Minter (first round) Halle Cioffi (second round) Leila Meskhi (first round)| First round | Second round | Quarterfinals | Semifinals | Final | ||||||||||||||||||||||||||||||
| 1 | Z Garrison | 7 | 6 | |||||||||||||||||||||||||||||||
 K Schimper | 6 | 1 | 1 | Z Garrison | 6 | 6 | ||||||||||||||||||||||||||||
| S Parkhomenko | 4 | 6 | 2 | N Bykova | 0 | 3 | ||||||||||||||||||||||||||||
| N Bykova | 6 | 4 | 6 | 1 | Z Garrison | 6 | 7 | |||||||||||||||||||||||||||
| R Fairbank | 7 | 6 | H Na | 1 | 6 | |||||||||||||||||||||||||||||
| Q | S Stafford | 5 | 3 | R Fairbank | 1 | 1 | ||||||||||||||||||||||||||||
| H Na | 7 | 7 | H Na | 6 | 6 | |||||||||||||||||||||||||||||
| 8 | L Meskhi | 6 | 6 | 1 | Z Garrison | 6 | 6 | |||||||||||||||||||||||||||
| 4 | L Savchenko | 6 | 6 | 6 | Q | L Allen | 3 | 4 | ||||||||||||||||||||||||||
| J Mundel | 3 | 7 | 0 | 4 | L Savchenko | 1 | 6 | 2 | ||||||||||||||||||||||||||
| B Herr | 6 | 2 | 2 | Q | L Allen | 6 | 2 | 6 | ||||||||||||||||||||||||||
| Q | L Allen | 4 | 6 | 6 | Q | L Allen | 6 | 6 | ||||||||||||||||||||||||||
| R Reis | 6 | 6 | Q | S Martin | 3 | 1 | ||||||||||||||||||||||||||||
| Q | L Gregory | 3 | 2 | R Reis | 3 | 2 | ||||||||||||||||||||||||||||
| Q | S Martin | 6 | 6 | Q | S Martin | 6 | 6 | |||||||||||||||||||||||||||
| 6 | A Minter | 3 | 4 | 1 | Zina Garrison | 3 | 6 | 2 | ||||||||||||||||||||||||||
| 7 | H Cioffi | 6 | 6 | 2 | Katerina Maleeva | 6 | 2 | 6 | ||||||||||||||||||||||||||
 A Kijimuta | 1 | 3 | 7 | H Cioffi | 1 | 4 | ||||||||||||||||||||||||||||
| S Reece | 2 | 3 | G Magers | 6 | 6 | |||||||||||||||||||||||||||||
| G Magers | 6 | 6 | G Magers | 7 | 3 | 4 | ||||||||||||||||||||||||||||
| M L Daniels | 6 | 6 | 6 | 3 | S Rehe | 5 | 6 | 6 | ||||||||||||||||||||||||||
| E Burgin | 7 | 3 | 4 | M L Daniels | 1 | 4 | ||||||||||||||||||||||||||||
| B Bowes | 6 | 1 | 4 | 3 | S Rehe | 6 | 6 | |||||||||||||||||||||||||||
| 3 | S Rehe | 3 | 6 | 6 | 3 | S Rehe | 2 | 0 | ||||||||||||||||||||||||||
| 5 | H Kelesi | 5 | 4 | 2 | K Maleeva | 6 | 6 | |||||||||||||||||||||||||||
| A Frazier | 7 | 6 | A Frazier | 6 | 6 | |||||||||||||||||||||||||||||
| M Werdel | 6 | 6 | M Werdel | 1 | 2 | |||||||||||||||||||||||||||||
 I Kuczyńska | 4 | 4 | A Frazier | 6 | 2 | 2 | ||||||||||||||||||||||||||||
| A Grossman | 6 | 6 | 2 | K Maleeva | 2 | 6 | 6 | |||||||||||||||||||||||||||
| M Torres | 2 | 4 | A Grossman | 6 | 6 | 6 | ||||||||||||||||||||||||||||
| A Henricksson | 3 | 7 | 3 | 2 | K Maleeva | 7 | 4 | 7 | ||||||||||||||||||||||||||
| 2 | K Maleeva | 6 | 6 | 6 | ||||||||||||||||||||||||||||||
Chris Evert was the defending champion but did not compete that year.
Steffi Graf was the defending champion and won in the final 6–4, 6–4 against Chris Evert.
Chris Evert was the defending champion and won in the final 7–6, 6–4 against Arantxa Sánchez.
Mercedes Paz and Eva Pfaff were the defending champions but they competed with different partners that year, Paz with Mary-Lou Daniels and Pfaff with Zina Garrison.
Steffi Graf was the defending champion but lost in the semifinals to Gabriela Sabatini.
Steffi Graf was the defending champion and won in the final 6–1, 6–4 against Kimiko Date.
Gigi Fernández and Natasha Zvereva were the defending champions but lost in the final 7–5, 2–6, 6–3 against Jana Novotná and Arantxa Sánchez Vicario.
Arantxa Sánchez Vicario was the defending champion but lost in the quarterfinals to Brenda Schultz.
Kathleen Horvath was the defending champion but lost in the first round to Silvia La Fratta.
Bettina Bunge and Katerina Maleeva were the defending champions but only Maleeva competed that year with Raffaella Reggi.
Steffi Graf was the defending champion but did not compete that year.
Chris Evert was the defending champion but lost in the final 3–6, 6–1, 6–4 against Monica Seles.
Barbara Potter won in the final 6–2, 6–2 against Helen Kelesi.
Steffi Graf was the defending champion but did not compete that year.
Jenny Byrne and Michelle Jaggard were the defending champions but they competed with different partners that year, Byrne with Janine Tremelling and Jaggard with Katerina Maleeva.
First-seeded Martina Navratilova was the defending champion and won in the final 6–2, 6–2 against Chris Evert. This was the 80th and the last time these two legends faced each other in a professional match with Navratilova ending the rivalry 43–37 in her favour.
Pam Shriver and Natasha Zvereva were the defending champions but they competed with different partners that year, Shriver with Martina Navratilova and Zvereva with Gigi Fernández.
Martina Navratilova was the defending champion but lost in the finals to top seed Monica Seles 3–6, 6–2, 6–1.
Top-seeded Manuela Maleeva was the defending champion but fell in the quarterfinals to Kate Gompert. Fourth-seed Andrea Temesvári claimed the title and $38,000 first prize money by defeating Zina Garrison in the final.
Seventh-seeded sisters Katerina Maleeva and Manuela Maleeva claimed the title by defeating third-seeds Penny Barg and Paula Smith in the final.